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Protein

GTP-binding protein ypt4

Gene

ypt4

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi16 – 23GTPSequence analysis8
Nucleotide bindingi68 – 72GTPSequence analysis5

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport
LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-SPO-6798695. Neutrophil degranulation.
R-SPO-8854214. TBC/RABGAPs.
R-SPO-8873719. RAB geranylgeranylation.

Names & Taxonomyi

Protein namesi
Recommended name:
GTP-binding protein ypt4
Gene namesi
Name:ypt4
ORF Names:SPAC1B3.11c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC1B3.11c.
PomBaseiSPAC1B3.11c. ypt4.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001213111 – 234GTP-binding protein ypt4Add BLAST234

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi233S-geranylgeranyl cysteineBy similarity1
Lipidationi234S-geranylgeranyl cysteineBy similarity1

Keywords - PTMi

Lipoprotein, Prenylation

Proteomic databases

MaxQBiO13876.
PRIDEiO13876.

Interactioni

Protein-protein interaction databases

BioGridi278589. 9 interactors.
MINTiMINT-4668686.
STRINGi4896.SPAC1B3.11c.1.

Structurei

3D structure databases

ProteinModelPortaliO13876.
SMRiO13876.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi39 – 47Effector regionBy similarity9

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

HOGENOMiHOG000233968.
InParanoidiO13876.
KOiK07880.
OMAiQNICILL.
OrthoDBiEOG092C5MDH.
PhylomeDBiO13876.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS51419. RAB. 1 hit.

Sequencei

Sequence statusi: Complete.

O13876-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKESYDYLV KIVLAGPSGT GKSCLLQRFV KNQWDDQVSH TVGIDFASRI
60 70 80 90 100
ISVGMGNQQK RIKLQIWDTA GQEKFRSVAR NYYRGAAGAV LVYDVTNKDS
110 120 130 140 150
FEELSSWLSD IRAMAPSTIC VVLAGSKSDL QNQRQVSTEE AAEFCSEKHI
160 170 180 190 200
SSAHETSSYT GSNVEECFLS VVSTIITRIE LGEIDPQDQS LGIQYGDLSF
210 220 230
RRPVHPSSTS NWWTSITNWD DLVRLERQTR SYCC
Length:234
Mass (Da):26,269
Last modified:January 1, 1998 - v1
Checksum:iD1C4FE1A4B3B5F6A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB11239.1.
PIRiT38030.
RefSeqiNP_594796.1. NM_001020224.2.

Genome annotation databases

EnsemblFungiiSPAC1B3.11c.1; SPAC1B3.11c.1:pep; SPAC1B3.11c.
GeneIDi2542113.
KEGGispo:SPAC1B3.11c.

Similar proteinsi

Entry informationi

Entry nameiYPT4_SCHPO
AccessioniPrimary (citable) accession number: O13876
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: September 27, 2017
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families