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O13857 (PLB2_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative lysophospholipase C1A6.03c

EC=3.1.1.5
Alternative name(s):
Phospholipase B
Gene names
ORF Names:SPAC1A6.03c
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length666 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the release of fatty acids from lysophospholipids By similarity.

Catalytic activity

2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.

Subcellular location

Secreted Probable.

Sequence similarities

Belongs to the lysophospholipase family.

Contains 1 PLA2c domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 666647Putative lysophospholipase C1A6.03c
PRO_0000024641

Regions

Domain76 – 617542PLA2c

Amino acid modifications

Glycosylation741N-linked (GlcNAc...) Potential
Glycosylation1271N-linked (GlcNAc...) Potential
Glycosylation1621N-linked (GlcNAc...) Potential
Glycosylation1961N-linked (GlcNAc...) Potential
Glycosylation2661N-linked (GlcNAc...) Potential
Glycosylation2741N-linked (GlcNAc...) Potential
Glycosylation3031N-linked (GlcNAc...) Potential
Glycosylation3761N-linked (GlcNAc...) Potential
Glycosylation4061N-linked (GlcNAc...) Potential
Glycosylation4111N-linked (GlcNAc...) Potential
Glycosylation4831N-linked (GlcNAc...) Potential
Glycosylation5181N-linked (GlcNAc...) Potential
Glycosylation5231N-linked (GlcNAc...) Potential
Glycosylation5471N-linked (GlcNAc...) Potential
Glycosylation5561N-linked (GlcNAc...) Potential
Glycosylation5741N-linked (GlcNAc...) Potential
Glycosylation5961N-linked (GlcNAc...) Potential
Glycosylation6131N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
O13857 [UniParc].

Last modified April 18, 2012. Version 3.
Checksum: 823C53C20530CDF8

FASTA66673,586
        10         20         30         40         50         60 
MLFNCFGILA LLQILPALAY PPCREQMSDP YEFGESDLMR PGMHDTPLSL MQKREALAIS 

        70         80         90        100        110        120 
LSKRDSVGSY APYNVTCPSD YMLRPASDGI SSGEQSFIDK RIPKINTQMR SFISNTGLDV 

       130        140        150        160        170        180 
DVNSVINDSD GPRLGLAFSG GGLRAMVHGG GVLNAFDSRN GNGSSLAGIL QSAMYIAGLS 

       190        200        210        220        230        240 
GGSWLVGSVA VNNFANITYL RDNVWNLEHS VFAPHGDNVV ENLAYYDDLD DEIDQKKDAG 

       250        260        270        280        290        300 
FDTSLTDLWG RALSRKLVDA TQGGPNITFS SIRNQTWFQN ADYPYPIIIS DSRLEEEKAI 

       310        320        330        340        350        360 
PANTSIFEFT PYEFGTWDNG IKAFLPMEYV GTHLKNGVPP DHKCIRNYDN AGFVMGTSAT 

       370        380        390        400        410        420 
LFNTFLLEWS QEVTSNSTLY DIIHKVFEKL SEDQNDIAPY PNPYQNFTTT NTTVKNPFER 

       430        440        450        460        470        480 
FDTIDLVDGG EDDENIPIWP LLHPQRFVDV IFAVDATYDD SNGWPDGSSI VTTYERIITY 

       490        500        510        520        530        540 
NANKSVDVRG FPYIPDEDTI ISLGLNTHPT FFGCDGRNTT AGNHTVDNNT PPLLVYFPNY 

       550        560        570        580        590        600 
PWVYYSNIST FTMSMNDTLS SGILENAALS ATQNNSDSFA VCLACAMIQR SLERKNMSTP 

       610        620        630        640        650        660 
SQCSSCFEQY CWNGTTVNNP SAVSNYAPTV LSASTTSGTS STTKASPTHT PWYESLFDLK 


ELKSID 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"Comparative functional genomics of the fission yeasts."
Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N., Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y., Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K. expand/collapse author list , Bayne E.H., Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G., French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A., Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P., Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R., Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J., Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W., Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.
Science 332:930-936(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: REVISION OF GENE MODEL.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329670 Genomic DNA. Translation: CAB16353.3.
PIRT38006.
RefSeqNP_593194.3. NM_001018590.3.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid278694. 119 interactions.
MINTMINT-4668554.
STRING4896.SPAC1A6.03c-1.

Proteomic databases

MaxQBO13857.
PaxDbO13857.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPAC1A6.03c.1; SPAC1A6.03c.1:pep; SPAC1A6.03c.
GeneID2542220.
KEGGspo:SPAC1A6.03c.

Organism-specific databases

PomBaseSPAC1A6.03c.

Phylogenomic databases

eggNOGNOG271081.
HOGENOMHOG000189547.
KOK13333.
OrthoDBEOG7N37NC.

Family and domain databases

InterProIPR016035. Acyl_Trfase/lysoPLipase.
IPR002642. LysoPLipase_cat_dom.
[Graphical view]
PfamPF01735. PLA2_B. 1 hit.
[Graphical view]
SMARTSM00022. PLAc. 1 hit.
[Graphical view]
SUPFAMSSF52151. SSF52151. 1 hit.
PROSITEPS51210. PLA2C. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20803289.

Entry information

Entry namePLB2_SCHPO
AccessionPrimary (citable) accession number: O13857
Entry history
Integrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: April 18, 2012
Last modified: May 14, 2014
This is version 85 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names