O13856 (YEX2_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized WD repeat-containing protein C1A6.02

Gene names

ORF Names:

SPAC1A6.02, SPAC23C4.21

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]

Taxonomic identifier

284812 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › Schizosaccharomyces pombe

Protein attributes

Sequence length	361 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Subcellular location	Nucleus › nucleolus Ref.2.
Sequence similarities	Contains 6 WD repeats.

Ontologies

Keywords
Cellular component	Nucleus
Domain	Repeat WD repeat
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ribosomal small subunit biogenesis Inferred from sequence orthology. Source: PomBase
Cellular_component	nucleolus Inferred from direct assay Ref.2. Source: PomBase protein complex Non-traceable author statement. Source: PomBase
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 361	361	Uncharacterized WD repeat-containing protein C1A6.02		PRO_0000051486
Regions
	Repeat	57 – 96	40	WD 1
	Repeat	103 – 142	40	WD 2
	Repeat	146 – 184	39	WD 3
	Repeat	187 – 229	43	WD 4
	Repeat	237 – 275	39	WD 5
	Repeat	280 – 318	39	WD 6

Sequences

	Sequence		Length	Mass (Da)
	O13856 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 38DD785710325C03	FASTA	361	39,780
	10 20 30 40 50 60 MGGTINAAIK QKFENEIFDL ACFGENQVLL GFSNGRVSSY QYDVAQISLV EQWSTKRHKK 70 80 90 100 110 120 SCRNISVNES GTEFISVGSD GVLKIADTST GRVSSKWIVD KNKEISPYSV VQWIENDMVF 130 140 150 160 170 180 ATGDDNGCVS VWDKRTEGGI IHTHNDHIDY ISSISPFEER YFVATSGDGV LSVIDARNFK 190 200 210 220 230 240 KPILSEEQDE EMTCGAFTRD QHSKKKFAVG TASGVITLFT KGDWGDHTDR ILSPIRSHDF 250 260 270 280 290 300 SIETITRADS DSLYVGGSDG CIRLLHILPN KYERIIGQHS SRSTVDAVDV TTEGNFLVSC 310 320 330 340 350 360 SGTELAFWPV DQKEGDESSS SDNLDSDEDS SSDSEFSSPK KKKKVGNQGK KPLGTDFFDG L

References

[1]

"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843.

[2]

"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe." Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M. Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU329670 Genomic DNA. Translation: CAB16892.2.
PIR	T38005.
RefSeq	XP_001713048.1. XM_001712996.2.
3D structure databases
ProteinModelPortal	O13856.
ModBase	Search...
Protein-protein interaction databases
STRING	4896.SPAC1A6.02-1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	SPAC1A6.02.1; SPAC1A6.02.1:pep; SPAC1A6.02.
GeneID	3361484.
KEGG	spo:SPAC1A6.02.
Organism-specific databases
PomBase	SPAC1A6.02.
Phylogenomic databases
eggNOG	NOG297173.
OMA	WDTRQRS.
OrthoDB	EOG4HQHTP.
Family and domain databases
Gene3D	2.130.10.10. 2 hits.
InterPro	IPR015943. WD40/YVTN_repeat-like_dom. IPR001680. WD40_repeat. IPR017986. WD40_repeat_dom. IPR017422. WD_repeat_p55. [Graphical view]
PIRSF	PIRSF038169. WD_repeat_p55. 1 hit.
SMART	SM00320. WD40. 5 hits. [Graphical view]
SUPFAM	SSF50978. WD40_like. 1 hit.
PROSITE	PS00678. WD_REPEATS_1. False negative. PS50082. WD_REPEATS_2. False negative. PS50294. WD_REPEATS_REGION. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20811527.

Entry information

Entry name

YEX2_SCHPO

Accession

Primary (citable) accession number: O13856
Secondary accession number(s): Q1K9B5

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 16, 2004
Last sequence update:	January 1, 1998
Last modified:	April 3, 2013
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program