O13843 (ALLA_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable ureidoglycolate hydrolase
EC=3.5.3.19

Gene names

ORF Names:

SPAC19G12.04

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Taxonomic identifier

284812 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length	191 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Utilization of purines as secondary nitrogen sources, when primary sources are limiting By similarity.
Catalytic activity	(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2.
Pathway	Nitrogen metabolism; (S)-allantoin degradation; glyoxylate from (S)-ureidoglycolate: step 1/1.
Sequence similarities	Belongs to the ureidoglycolate hydrolase family.

Ontologies

Keywords
Biological process	Purine metabolism
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	allantoin catabolic process Inferred from sequence or structural similarity. Source: GeneDB_Spombe purine base catabolic process Inferred from sequence or structural similarity. Source: GeneDB_Spombe
Cellular component	cytosol Inferred from direct assay. Source: GeneDB_Spombe nucleus Inferred from direct assay. Source: GeneDB_Spombe
Molecular function	ureidoglycolate hydrolase activity Inferred from sequence or structural similarity. Source: GeneDB_Spombe
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 191	191	Probable ureidoglycolate hydrolase		PRO_0000120561

Sequences

	Sequence		Length	Mass (Da)
	O13843 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 7E5F412FD013DF6F	FASTA	191	20,890
	10 20 30 40 50 60 MEAKKIYAQA LTDEAFAPFG SVVQQKDDVK MVSANGGTAK KYLKVSESIQ NYEKSSSAST 70 80 90 100 110 120 RKGVWNFFST HPSVHPANDE HAAFQISVLE RHPFTTQTFI PMCRSSDEQA YLIAVAPNAP 130 140 150 160 170 180 DGMPDWNQTQ AFVAKGAQGV TYSAGVWHAP MVTIGKETML AAFNYENGVA EDDCQVQSTE 190 SPIEVFIKIS T

References

[1]

"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU329670 Genomic DNA. Translation: CAB10115.1.
PIR	T37991.
RefSeq	NP_594419.1. NM_001019848.1.
3D structure databases
ProteinModelPortal	O13843.
ModBase	Search...
Protein-protein interaction databases
STRING	O13843.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	SPAC19G12.04.1; SPAC19G12.04.1:pep; SPAC19G12.04.
GeneID	2542470.
KEGG	spo:SPAC19G12.04.
NMPDR	fig|4896.1.peg.4389.
Organism-specific databases
GeneDB_Spombe	SPAC19G12.04.
Phylogenomic databases
eggNOG	fuNOG10612.
GeneTree	EFGT00050000006324.
HOGENOM	HBG289179.
OMA	IETEGAK.
OrthoDB	EOG4RJKB5.
Enzyme and pathway databases
BioCyc	SPOM-XXX-01:SPOM-XXX-01-002528-MONOMER.
Gene expression databases
ArrayExpress	O13843.
Family and domain databases
InterPro	IPR011051. Cupin_RmlC_type. IPR007247. Ureidogly_hydro. IPR024060. Ureidoglycolate_hydrolase_dom. [Graphical view]
Gene3D	G3DSA:2.60.120.480. G3DSA:2.60.120.480. 1 hit.
KO	K01483.
PANTHER	PTHR21221. Ureidogly_hydro. 1 hit.
Pfam	PF04115. Ureidogly_hydro. 1 hit. [Graphical view]
PIRSF	PIRSF017306. Ureidogly_hydro. 1 hit.
SUPFAM	SSF51182. RmlC_like_cupin. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALLA_SCHPO

Accession

Primary (citable) accession number: O13843

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	January 1, 1998
Last modified:	December 14, 2011
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program