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Protein

Chitin deacetylase 1

Gene

cda1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin. Required for proper spore formation.1 Publication

Catalytic activityi

Chitin + H2O = chitosan + acetate.

GO - Molecular functioni

GO - Biological processi

  • ascospore wall assembly Source: PomBase
  • ascospore wall chitin catabolic process Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation, Sporulation

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-3192-MONOMER.
BRENDAi3.5.1.41. 5613.

Names & Taxonomyi

Protein namesi
Recommended name:
Chitin deacetylase 1 (EC:3.5.1.41)
Gene namesi
Name:cda1
ORF Names:SPAC19G12.03
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC19G12.03.
PomBaseiSPAC19G12.03. cda1.

Subcellular locationi

GO - Cellular componenti

  • chitosan layer of spore wall Source: PomBase
  • cytosol Source: PomBase
  • nucleus Source: PomBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 320320Chitin deacetylase 1PRO_0000172745Add
BLAST

Proteomic databases

MaxQBiO13842.

Interactioni

Subunit structurei

Homodimer.1 Publication

Protein-protein interaction databases

BioGridi278697. 9 interactions.
MINTiMINT-1346769.

Structurei

3D structure databases

ProteinModelPortaliO13842.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini69 – 303235NodB homologyPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the polysaccharide deacetylase family.Curated
Contains 1 NodB homology domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000259472.
InParanoidiO13842.
OMAiDHIEQHD.
OrthoDBiEOG7K3TX8.
PhylomeDBiO13842.

Family and domain databases

Gene3Di3.20.20.370. 1 hit.
InterProiIPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR002509. NODB_dom.
[Graphical view]
PfamiPF01522. Polysacc_deac_1. 1 hit.
[Graphical view]
SUPFAMiSSF88713. SSF88713. 1 hit.
PROSITEiPS51677. NODB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O13842-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYETRDLTGN AGKPVDTNPW PNNSKIAVSF VVNYEEGGER SLLYEDEGFE
60 70 80 90 100
TFLTEAGLMP FPNRPVRERS IESCFEYGSR CGFWRILNLF KKHKVPFTCW
110 120 130 140 150
AIGQAVEKNP VVVGAMEEAG CEVGSHSHRW INYEGVPPET EYEHIKKSVQ
160 170 180 190 200
AIQKASPSNS APRSWYTGRA SLNTRKLVCQ VYKDLGLPQP FDSDEYNDDY
210 220 230 240 250
PYWVADPLAS KPGAEDDKGL LIVPYTLEVN DMKYAVAPGF CNSDDFYTYA
260 270 280 290 300
RDAFDVLYEE GLEGAPKMMT IGLHCRLTGR PGRFRGLQKL MEHITSKEGV
310 320
WVATREQIAQ AWSAKHPYKA
Length:320
Mass (Da):36,207
Last modified:January 1, 1998 - v1
Checksum:i9DAD54FEAA8B1A68
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB10114.1.
PIRiT37990.
RefSeqiNP_594418.1. NM_001019847.2.

Genome annotation databases

EnsemblFungiiSPAC19G12.03.1; SPAC19G12.03.1:pep; SPAC19G12.03.
GeneIDi2542224.
KEGGispo:SPAC19G12.03.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB10114.1.
PIRiT37990.
RefSeqiNP_594418.1. NM_001019847.2.

3D structure databases

ProteinModelPortaliO13842.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi278697. 9 interactions.
MINTiMINT-1346769.

Proteomic databases

MaxQBiO13842.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC19G12.03.1; SPAC19G12.03.1:pep; SPAC19G12.03.
GeneIDi2542224.
KEGGispo:SPAC19G12.03.

Organism-specific databases

EuPathDBiFungiDB:SPAC19G12.03.
PomBaseiSPAC19G12.03. cda1.

Phylogenomic databases

HOGENOMiHOG000259472.
InParanoidiO13842.
OMAiDHIEQHD.
OrthoDBiEOG7K3TX8.
PhylomeDBiO13842.

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-3192-MONOMER.
BRENDAi3.5.1.41. 5613.

Miscellaneous databases

PROiO13842.

Family and domain databases

Gene3Di3.20.20.370. 1 hit.
InterProiIPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR002509. NODB_dom.
[Graphical view]
PfamiPF01522. Polysacc_deac_1. 1 hit.
[Graphical view]
SUPFAMiSSF88713. SSF88713. 1 hit.
PROSITEiPS51677. NODB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "cda1+, encoding chitin deacetylase is required for proper spore formation in Schizosaccharomyces pombe."
    Matsuo Y., Tanaka K., Matsuda H., Kawamukai M.
    FEBS Lett. 579:2737-2743(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBUNIT.

Entry informationi

Entry nameiCDA1_SCHPO
AccessioniPrimary (citable) accession number: O13842
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: January 1, 1998
Last modified: June 8, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.