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O13833

- CID1_SCHPO

UniProt

O13833 - CID1_SCHPO

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Protein

Poly(A) RNA polymerase protein cid1

Gene

cid1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Involved in cell cycle arrest where in association with crb2/rhp9 and chk1 it inhibits unscheduled mitosis.1 Publication

Cofactori

Mg2+By similarity, Mn2+By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi101 – 1011Magnesium or manganese; catalyticBy similarity
Metal bindingi103 – 1031Magnesium or manganese; catalyticBy similarity

GO - Molecular functioni

  1. magnesium ion binding Source: PomBase
  2. RNA binding Source: PomBase
  3. RNA uridylyltransferase activity Source: PomBase
  4. UTP binding Source: PomBase

GO - Biological processi

  1. biological regulation Source: PomBase
  2. polyuridylation-dependent decapping of nuclear-transcribed mRNA Source: PomBase
  3. RNA 3' uridylation Source: PomBase
  4. RNA polyadenylation Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Poly(A) RNA polymerase protein cid1 (EC:2.7.7.-)
Alternative name(s):
Caffeine-induced death protein 1
Gene namesi
Name:cid1
ORF Names:SPAC19D5.03
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485: Chromosome I

Organism-specific databases

PomBaseiSPAC19D5.03.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: PomBase
  2. cytosol Source: PomBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 405405Poly(A) RNA polymerase protein cid1PRO_0000120312Add
BLAST

Proteomic databases

MaxQBiO13833.

Interactioni

Protein-protein interaction databases

BioGridi278883. 28 interactions.
MINTiMINT-4668341.
STRINGi4896.SPAC19D5.03-1.

Structurei

Secondary structure

1
405
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi42 – 5514Combined sources
Helixi59 – 7719Combined sources
Beta strandi84 – 896Combined sources
Helixi90 – 934Combined sources
Beta strandi97 – 993Combined sources
Beta strandi102 – 1076Combined sources
Helixi118 – 12710Combined sources
Beta strandi130 – 1345Combined sources
Beta strandi143 – 15311Combined sources
Beta strandi159 – 1646Combined sources
Helixi166 – 18116Combined sources
Helixi185 – 19814Combined sources
Helixi204 – 2063Combined sources
Helixi211 – 22414Combined sources
Beta strandi226 – 2283Combined sources
Turni234 – 2363Combined sources
Helixi256 – 2583Combined sources
Helixi268 – 28114Combined sources
Turni285 – 2873Combined sources
Beta strandi288 – 2903Combined sources
Beta strandi292 – 2943Combined sources
Helixi301 – 3044Combined sources
Beta strandi325 – 3295Combined sources
Beta strandi331 – 3333Combined sources
Turni338 – 3414Combined sources
Helixi344 – 36118Combined sources
Beta strandi365 – 3673Combined sources
Helixi370 – 3745Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4E7XX-ray3.20A/B/C/D1-405[»]
4E80X-ray3.02A/B/C/D1-405[»]
4E8FX-ray2.60A/B1-405[»]
4EP7X-ray2.28A/B40-377[»]
4FH3X-ray2.00A33-377[»]
4FH5X-ray2.30A33-377[»]
4FHPX-ray2.50A33-377[»]
4FHVX-ray2.10A33-377[»]
4FHWX-ray2.50A33-377[»]
4FHXX-ray2.70A33-377[»]
4FHYX-ray2.70A33-377[»]
4NKTX-ray1.90A/B40-377[»]
4NKUX-ray1.94A/B40-377[»]
ProteinModelPortaliO13833.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini267 – 33670PAP-associatedAdd
BLAST

Sequence similaritiesi

Belongs to the DNA polymerase type-B-like family.Curated
Contains 1 PAP-associated domain.Curated

Phylogenomic databases

eggNOGiCOG5260.
InParanoidiO13833.
KOiK13291.
OMAiDMARIRG.
OrthoDBiEOG7R8396.
PhylomeDBiO13833.

Family and domain databases

InterProiIPR002934. Nucleotidyltransferase.
IPR002058. PAP_assoc.
[Graphical view]
PfamiPF01909. NTP_transf_2. 1 hit.
PF03828. PAP_assoc. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O13833-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNISSAQFIP GVHTVEEIEA EIHKNLHISK SCSYQKVPNS HKEFTKFCYE
60 70 80 90 100
VYNEIKISDK EFKEKRAALD TLRLCLKRIS PDAELVAFGS LESGLALKNS
110 120 130 140 150
DMDLCVLMDS RVQSDTIALQ FYEELIAEGF EGKFLQRARI PIIKLTSDTK
160 170 180 190 200
NGFGASFQCD IGFNNRLAIH NTLLLSSYTK LDARLKPMVL LVKHWAKRKQ
210 220 230 240 250
INSPYFGTLS SYGYVLMVLY YLIHVIKPPV FPNLLLSPLK QEKIVDGFDV
260 270 280 290 300
GFDDKLEDIP PSQNYSSLGS LLHGFFRFYA YKFEPREKVV TFRRPDGYLT
310 320 330 340 350
KQEKGWTSAT EHTGSADQII KDRYILAIED PFEISHNVGR TVSSSGLYRI
360 370 380 390 400
RGEFMAASRL LNSRSYPIPY DSLFEEAPIP PRRQKKTDEQ SNKKLLNETD

GDNSE
Length:405
Mass (Da):46,257
Last modified:November 1, 1999 - v2
Checksum:i0AA24B4411B61027
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB50789.1.
AF105076 mRNA. Translation: AAD16889.1.
PIRiT37963.
RefSeqiNP_594901.1. NM_001020330.2.

Genome annotation databases

EnsemblFungiiSPAC19D5.03.1; SPAC19D5.03.1:pep; SPAC19D5.03.
GeneIDi2542420.
KEGGispo:SPAC19D5.03.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB50789.1 .
AF105076 mRNA. Translation: AAD16889.1 .
PIRi T37963.
RefSeqi NP_594901.1. NM_001020330.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4E7X X-ray 3.20 A/B/C/D 1-405 [» ]
4E80 X-ray 3.02 A/B/C/D 1-405 [» ]
4E8F X-ray 2.60 A/B 1-405 [» ]
4EP7 X-ray 2.28 A/B 40-377 [» ]
4FH3 X-ray 2.00 A 33-377 [» ]
4FH5 X-ray 2.30 A 33-377 [» ]
4FHP X-ray 2.50 A 33-377 [» ]
4FHV X-ray 2.10 A 33-377 [» ]
4FHW X-ray 2.50 A 33-377 [» ]
4FHX X-ray 2.70 A 33-377 [» ]
4FHY X-ray 2.70 A 33-377 [» ]
4NKT X-ray 1.90 A/B 40-377 [» ]
4NKU X-ray 1.94 A/B 40-377 [» ]
ProteinModelPortali O13833.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 278883. 28 interactions.
MINTi MINT-4668341.
STRINGi 4896.SPAC19D5.03-1.

Proteomic databases

MaxQBi O13833.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii SPAC19D5.03.1 ; SPAC19D5.03.1:pep ; SPAC19D5.03 .
GeneIDi 2542420.
KEGGi spo:SPAC19D5.03.

Organism-specific databases

PomBasei SPAC19D5.03.

Phylogenomic databases

eggNOGi COG5260.
InParanoidi O13833.
KOi K13291.
OMAi DMARIRG.
OrthoDBi EOG7R8396.
PhylomeDBi O13833.

Miscellaneous databases

NextBioi 20803478.
PROi O13833.

Family and domain databases

InterProi IPR002934. Nucleotidyltransferase.
IPR002058. PAP_assoc.
[Graphical view ]
Pfami PF01909. NTP_transf_2. 1 hit.
PF03828. PAP_assoc. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cid1, a fission yeast protein required for S-M checkpoint control when DNA polymerase delta or epsilon is inactivated."
    Wang S.-W., Toda T., MacCallum R., Harris A.L., Norbury C.
    Mol. Cell. Biol. 20:3234-3244(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION.
    Strain: 972 / ATCC 24843.
  2. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiCID1_SCHPO
AccessioniPrimary (citable) accession number: O13833
Secondary accession number(s): O94608
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: November 1, 1999
Last modified: November 26, 2014
This is version 100 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3