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O13833

- CID1_SCHPO

UniProt

O13833 - CID1_SCHPO

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Protein
Poly(A) RNA polymerase protein cid1
Gene
cid1, SPAC19D5.03
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Involved in cell cycle arrest where in association with crb2/rhp9 and chk1 it inhibits unscheduled mitosis.1 Publication

Cofactori

Magnesium or manganese By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi101 – 1011Magnesium or manganese; catalytic By similarity
Metal bindingi103 – 1031Magnesium or manganese; catalytic By similarity

GO - Molecular functioni

  1. RNA binding Source: PomBase
  2. RNA uridylyltransferase activity Source: PomBase
  3. UTP binding Source: PomBase
  4. magnesium ion binding Source: PomBase

GO - Biological processi

  1. RNA 3' uridylation Source: PomBase
  2. RNA polyadenylation Source: PomBase
  3. biological regulation Source: PomBase
  4. mitotic nuclear division Source: UniProtKB-KW
  5. polyuridylation-dependent decapping of nuclear-transcribed mRNA Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Poly(A) RNA polymerase protein cid1 (EC:2.7.7.-)
Alternative name(s):
Caffeine-induced death protein 1
Gene namesi
Name:cid1
ORF Names:SPAC19D5.03
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485: Chromosome I

Organism-specific databases

PomBaseiSPAC19D5.03.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: PomBase
  2. cytosol Source: PomBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 405405Poly(A) RNA polymerase protein cid1
PRO_0000120312Add
BLAST

Proteomic databases

MaxQBiO13833.

Interactioni

Protein-protein interaction databases

BioGridi278883. 27 interactions.
MINTiMINT-4668341.
STRINGi4896.SPAC19D5.03-1.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi42 – 5514
Helixi59 – 7719
Beta strandi84 – 896
Helixi90 – 934
Beta strandi97 – 993
Beta strandi102 – 1076
Helixi118 – 12710
Beta strandi130 – 1345
Beta strandi143 – 15311
Beta strandi159 – 1646
Helixi166 – 18116
Helixi185 – 19814
Helixi204 – 2063
Helixi211 – 22414
Beta strandi226 – 2283
Turni234 – 2363
Helixi256 – 2583
Helixi268 – 28114
Turni285 – 2873
Beta strandi288 – 2903
Beta strandi292 – 2943
Helixi301 – 3044
Beta strandi325 – 3295
Beta strandi331 – 3333
Turni338 – 3414
Helixi344 – 36118
Beta strandi365 – 3673
Helixi370 – 3745

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4E7XX-ray3.20A/B/C/D1-405[»]
4E80X-ray3.02A/B/C/D1-405[»]
4E8FX-ray2.60A/B1-405[»]
4EP7X-ray2.28A/B40-377[»]
4FH3X-ray2.00A33-377[»]
4FH5X-ray2.30A33-377[»]
4FHPX-ray2.50A33-377[»]
4FHVX-ray2.10A33-377[»]
4FHWX-ray2.50A33-377[»]
4FHXX-ray2.70A33-377[»]
4FHYX-ray2.70A33-377[»]
4NKTX-ray1.90A/B40-377[»]
4NKUX-ray1.94A/B40-377[»]
ProteinModelPortaliO13833.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini267 – 33670PAP-associated
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG5260.
KOiK13291.
OMAiDMARIRG.
OrthoDBiEOG7R8396.
PhylomeDBiO13833.

Family and domain databases

InterProiIPR002934. Nucleotidyltransferase.
IPR002058. PAP_assoc.
[Graphical view]
PfamiPF01909. NTP_transf_2. 1 hit.
PF03828. PAP_assoc. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O13833-1 [UniParc]FASTAAdd to Basket

« Hide

MNISSAQFIP GVHTVEEIEA EIHKNLHISK SCSYQKVPNS HKEFTKFCYE    50
VYNEIKISDK EFKEKRAALD TLRLCLKRIS PDAELVAFGS LESGLALKNS 100
DMDLCVLMDS RVQSDTIALQ FYEELIAEGF EGKFLQRARI PIIKLTSDTK 150
NGFGASFQCD IGFNNRLAIH NTLLLSSYTK LDARLKPMVL LVKHWAKRKQ 200
INSPYFGTLS SYGYVLMVLY YLIHVIKPPV FPNLLLSPLK QEKIVDGFDV 250
GFDDKLEDIP PSQNYSSLGS LLHGFFRFYA YKFEPREKVV TFRRPDGYLT 300
KQEKGWTSAT EHTGSADQII KDRYILAIED PFEISHNVGR TVSSSGLYRI 350
RGEFMAASRL LNSRSYPIPY DSLFEEAPIP PRRQKKTDEQ SNKKLLNETD 400
GDNSE 405
Length:405
Mass (Da):46,257
Last modified:November 1, 1999 - v2
Checksum:i0AA24B4411B61027
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329670 Genomic DNA. Translation: CAB50789.1.
AF105076 mRNA. Translation: AAD16889.1.
PIRiT37963.
RefSeqiNP_594901.1. NM_001020330.2.

Genome annotation databases

EnsemblFungiiSPAC19D5.03.1; SPAC19D5.03.1:pep; SPAC19D5.03.
GeneIDi2542420.
KEGGispo:SPAC19D5.03.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329670 Genomic DNA. Translation: CAB50789.1 .
AF105076 mRNA. Translation: AAD16889.1 .
PIRi T37963.
RefSeqi NP_594901.1. NM_001020330.2.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4E7X X-ray 3.20 A/B/C/D 1-405 [» ]
4E80 X-ray 3.02 A/B/C/D 1-405 [» ]
4E8F X-ray 2.60 A/B 1-405 [» ]
4EP7 X-ray 2.28 A/B 40-377 [» ]
4FH3 X-ray 2.00 A 33-377 [» ]
4FH5 X-ray 2.30 A 33-377 [» ]
4FHP X-ray 2.50 A 33-377 [» ]
4FHV X-ray 2.10 A 33-377 [» ]
4FHW X-ray 2.50 A 33-377 [» ]
4FHX X-ray 2.70 A 33-377 [» ]
4FHY X-ray 2.70 A 33-377 [» ]
4NKT X-ray 1.90 A/B 40-377 [» ]
4NKU X-ray 1.94 A/B 40-377 [» ]
ProteinModelPortali O13833.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 278883. 27 interactions.
MINTi MINT-4668341.
STRINGi 4896.SPAC19D5.03-1.

Proteomic databases

MaxQBi O13833.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii SPAC19D5.03.1 ; SPAC19D5.03.1:pep ; SPAC19D5.03 .
GeneIDi 2542420.
KEGGi spo:SPAC19D5.03.

Organism-specific databases

PomBasei SPAC19D5.03.

Phylogenomic databases

eggNOGi COG5260.
KOi K13291.
OMAi DMARIRG.
OrthoDBi EOG7R8396.
PhylomeDBi O13833.

Miscellaneous databases

NextBioi 20803478.
PROi O13833.

Family and domain databases

InterProi IPR002934. Nucleotidyltransferase.
IPR002058. PAP_assoc.
[Graphical view ]
Pfami PF01909. NTP_transf_2. 1 hit.
PF03828. PAP_assoc. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cid1, a fission yeast protein required for S-M checkpoint control when DNA polymerase delta or epsilon is inactivated."
    Wang S.-W., Toda T., MacCallum R., Harris A.L., Norbury C.
    Mol. Cell. Biol. 20:3234-3244(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION.
    Strain: 972 / ATCC 24843.
  2. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiCID1_SCHPO
AccessioniPrimary (citable) accession number: O13833
Secondary accession number(s): O94608
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: November 1, 1999
Last modified: September 3, 2014
This is version 97 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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