Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized helicase C17H9.02

Gene

SPAC17H9.02

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi147 – 1548ATPPROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

  • ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process Source: PomBase
  • nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription Source: PomBase
  • nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts Source: PomBase
  • regulation of heterochromatin domain assembly Source: PomBase
  • regulation of heterochromatin island assembly Source: PomBase
  • regulation of snoRNA processing Source: PomBase
  • regulation of telomere maintenance via telomerase Source: PomBase
  • rRNA processing Source: PomBase
  • tRNA catabolic process Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Helicase, Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized helicase C17H9.02 (EC:3.6.4.-)
Gene namesi
ORF Names:SPAC17H9.02
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC17H9.02.
PomBaseiSPAC17H9.02.

Subcellular locationi

GO - Cellular componenti

  • heterochromatin island Source: PomBase
  • MTREC complex Source: PomBase
  • nuclear body Source: PomBase
  • nucleolus Source: PomBase
  • nucleus Source: PomBase
  • NURS complex Source: PomBase
  • TRAMP complex Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10301030Uncharacterized helicase C17H9.02PRO_0000102099Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei41 – 411Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO13799.

PTM databases

iPTMnetiO13799.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
pla1Q102952EBI-8993901,EBI-7997221
red1Q9UTR84EBI-8993901,EBI-1117407
SPAC140.04Q9P7B73EBI-8993901,EBI-9002253
SPBC20F10.05O429753EBI-8993901,EBI-9003631

Protein-protein interaction databases

BioGridi278648. 267 interactions.
IntActiO13799. 13 interactions.
MINTiMINT-4668081.

Structurei

3D structure databases

ProteinModelPortaliO13799.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini134 – 290157Helicase ATP-bindingPROSITE-ProRule annotationAdd
BLAST
Domaini357 – 561205Helicase C-terminalPROSITE-ProRule annotationAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi238 – 2414DEVH box

Sequence similaritiesi

Belongs to the helicase family. SKI2 subfamily.Curated
Contains 1 helicase ATP-binding domain.PROSITE-ProRule annotation
Contains 1 helicase C-terminal domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000163047.
InParanoidiO13799.
KOiK12598.
OrthoDBiEOG7WT48P.
PhylomeDBiO13799.

Family and domain databases

Gene3Di3.40.50.300. 3 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR025696. rRNA_proc-arch_dom.
IPR016438. Ski2.
IPR012961. Ski2_C.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF08148. DSHCT. 1 hit.
PF00271. Helicase_C. 1 hit.
PF13234. rRNA_proc-arch. 1 hit.
[Graphical view]
PIRSFiPIRSF005198. Antiviral_helicase_SKI2. 1 hit.
SMARTiSM00487. DEXDc. 1 hit.
SM01142. DSHCT. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O13799-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSENSTDSKN FQFSEGSRES SNDELKVLLR DTETKEDEKS SFSNSEEESI
60 70 80 90 100
IENLSDSSVN KEYAKNSLKL SDAVSESKYL NPLLKDKRHD RSFALHKVVV
110 120 130 140 150
PDDYDYIPLN KHIPSDPPAK TYPFELDPFQ STAIKCVERM ESVLVSAHTS
160 170 180 190 200
AGKTVIAEYA IAQALKNRQR VIYTSPIKSL SNQKYRELLS EFGDVGLMTG
210 220 230 240 250
DVSINPSASC LIMTTEILRA MLYKNSEIMH EIAWVIFDEV HYMRDKDRGV
260 270 280 290 300
VWEETLILLP DAIRFIFLSA TLPNALQFAR WISEIHKQPC HVVYTDYRPT
310 320 330 340 350
PLQHFIYPQG ADGIYMLVDE KNKFKTENFK KVLEVLDHST RQENYSKSSK
360 370 380 390 400
KVKKSSSLER IINMVLSNRY DPIIVFCFSK KECEINAHQF GKLDLNDTEN
410 420 430 440 450
KELVTEIFDS AINQLSEEDR GLRQFEEMRS LLLRGIGIHH SGLLPILKEL
460 470 480 490 500
VEILFQEGLV RILFATETFS IGLNMPARTV LFTKAQKFSG NNFRWLTSGE
510 520 530 540 550
YMQMSGRAGR RGIDTKGLSI VILDQSIDEQ AARCLMNGQA DVLNSAFHLS
560 570 580 590 600
YGMILNLMRI EEISPEDILK KSFYQFQNME SLPLIKEELM QLKNEETSIN
610 620 630 640 650
IPNETAVKEF HDLKLQLEKY GEEIQKVMTH PDNCLPYLQS GRLIQIKLGG
660 670 680 690 700
IIFPWGVLVN VIKREFDPNT REQVAPHETY VLDVLLPISS NSMSNHKVNP
710 720 730 740 750
SILVPPRPNE TPLYEIVSVL LTAVCNISSI RIYMPRELNS NESKLRAYRR
760 770 780 790 800
VNEVIEEFKE IPYLDPLEHM HIESSTLSLS LRKLEILEPK LFDSPYYKDS
810 820 830 840 850
KHRAEYHEFR KKLNLRAQIK DISTKITNTE AIIQLRELKI RQRVLRRLGF
860 870 880 890 900
CTLENVIDIK GRVACEITSG DELLLVELIF QGFFNQMPPE EIAAALSCFV
910 920 930 940 950
YEDKSEVSTL NLKEPFKKMY LTIIEAAKRI ATVSLESKLQ FNESDYLHQF
960 970 980 990 1000
KPDIMEPVSL WINGASFQEI CIVSKLYEGS IVRTFRRLDE LLKQLEHAAI
1010 1020 1030
VLGNNELKEK SVLTEQKLHR DIIFSASLYL
Length:1,030
Mass (Da):118,461
Last modified:January 1, 1998 - v1
Checksum:i1E088BCE01118789
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB11211.1.
PIRiT37868.
RefSeqiNP_593572.1. NM_001019004.2.

Genome annotation databases

EnsemblFungiiSPAC17H9.02.1; SPAC17H9.02.1:pep; SPAC17H9.02.
GeneIDi2542173.
KEGGispo:SPAC17H9.02.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB11211.1.
PIRiT37868.
RefSeqiNP_593572.1. NM_001019004.2.

3D structure databases

ProteinModelPortaliO13799.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi278648. 267 interactions.
IntActiO13799. 13 interactions.
MINTiMINT-4668081.

PTM databases

iPTMnetiO13799.

Proteomic databases

MaxQBiO13799.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC17H9.02.1; SPAC17H9.02.1:pep; SPAC17H9.02.
GeneIDi2542173.
KEGGispo:SPAC17H9.02.

Organism-specific databases

EuPathDBiFungiDB:SPAC17H9.02.
PomBaseiSPAC17H9.02.

Phylogenomic databases

HOGENOMiHOG000163047.
InParanoidiO13799.
KOiK12598.
OrthoDBiEOG7WT48P.
PhylomeDBiO13799.

Miscellaneous databases

PROiO13799.

Family and domain databases

Gene3Di3.40.50.300. 3 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR025696. rRNA_proc-arch_dom.
IPR016438. Ski2.
IPR012961. Ski2_C.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF08148. DSHCT. 1 hit.
PF00271. Helicase_C. 1 hit.
PF13234. rRNA_proc-arch. 1 hit.
[Graphical view]
PIRSFiPIRSF005198. Antiviral_helicase_SKI2. 1 hit.
SMARTiSM00487. DEXDc. 1 hit.
SM01142. DSHCT. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-41, IDENTIFICATION BY MASS SPECTROMETRY.

Entry informationi

Entry nameiYE02_SCHPO
AccessioniPrimary (citable) accession number: O13799
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: June 8, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.