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Protein

Small glutamine-rich tetratricopeptide repeat-containing protein 2

Gene

sgt2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Co-chaperone that binds to the molecular chaperone Hsp70 and regulates Hsp70 ATPase activity.By similarity

GO - Biological processi

Keywordsi

Molecular functionChaperone

Names & Taxonomyi

Protein namesi
Recommended name:
Small glutamine-rich tetratricopeptide repeat-containing protein 2
Gene namesi
Name:sgt2
ORF Names:SPAC1142.02c, SPAC17G6.19c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC1142.02c
PomBaseiSPAC1142.02c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003633771 – 317Small glutamine-rich tetratricopeptide repeat-containing protein 2Add BLAST317

Proteomic databases

MaxQBiO13797
PaxDbiO13797
PRIDEiO13797

PTM databases

iPTMnetiO13797

Interactioni

Protein-protein interaction databases

BioGridi278865, 17 interactors
STRINGi4896.SPAC1142.02c.1

Structurei

3D structure databases

ProteinModelPortaliO13797
SMRiO13797
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati14 – 48TPR 1Add BLAST35
Repeati83 – 116TPR 2Add BLAST34
Repeati118 – 150TPR 3Add BLAST33
Repeati151 – 184TPR 4Add BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi239 – 313Asn-richAdd BLAST75

Sequence similaritiesi

Belongs to the SGT family.Curated

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

HOGENOMiHOG000208193
InParanoidiO13797
KOiK16365
OMAiPAMMNMA
OrthoDBiEOG092C1UGR
PhylomeDBiO13797

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR032374 SGTA_dimer
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PfamiView protein in Pfam
PF16546 SGTA_dimer, 1 hit
PF13181 TPR_8, 1 hit
SMARTiView protein in SMART
SM00028 TPR, 3 hits
SUPFAMiSSF48452 SSF48452, 1 hit
PROSITEiView protein in PROSITE
PS50005 TPR, 3 hits
PS50293 TPR_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

O13797-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSNKVTAAI IDYLKQAITT GSISEEEKES LEVAAQCIQD SFKIKPEEIK
60 70 80 90 100
PKSGDRLVAA FEEYEKLHPV EEDSTAHVNK EEAEKLKLEG NNAIAAKDYQ
110 120 130 140 150
KALDLYTKAI EIDPTSPVYY SNRAAAYNQL GQFENAVEDA LTCLSLDPHH
160 170 180 190 200
ARAFGRLGRA KLSLGDAAAA ADAYKKGLDF DPNNEVLKRG LEAANKQLNQ
210 220 230 240 250
PSDSSATSGA DQARTSAGAA PDLGSIFGGG MPDLGSLMNN PAVMNMARNL
260 270 280 290 300
MQSGALNNIM NDPNIANMAR NFQSGGGMPD LSSLANNPQL QNLARNFMNN
310
NNNGNTDNNN QGNPPPQ
Length:317
Mass (Da):34,002
Last modified:January 1, 1998 - v1
Checksum:i7C4C147666BCD31F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB77009.1
PIRiT37851
RefSeqiXP_001713087.1, XM_001713035.2

Genome annotation databases

EnsemblFungiiSPAC1142.02c.1; SPAC1142.02c.1:pep; SPAC1142.02c
KEGGispo:SPAC1142.02c

Similar proteinsi

Entry informationi

Entry nameiSGT2_SCHPO
AccessioniPrimary (citable) accession number: O13797
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: January 1, 1998
Last modified: April 25, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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