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Protein

Peroxisomal ATPase pex6

Gene

pex6

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Component of the peroxisomal protein import machinery. Together with pex1, mediates the ATP-dependent relocation and recycling of the peroxisomal targeting signal-1 (PTS1) import receptor PEX5 from the peroxisomal membrane to the cytosol, where it is then available for another round of protein import into the organelle (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi695 – 7028ATPSequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Peroxisome biogenesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxisomal ATPase pex6
Alternative name(s):
Peroxin-6
Peroxisome biosynthesis protein pex6
Gene namesi
Name:pex6
ORF Names:SPAC17A5.01
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC17A5.01.
PomBaseiSPAC17A5.01. pex6.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • nucleus Source: PomBase
  • peroxisomal membrane Source: UniProtKB-SubCell
  • peroxisome Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 948948Peroxisomal ATPase pex6PRO_0000084619Add
BLAST

Proteomic databases

MaxQBiO13764.

Interactioni

Protein-protein interaction databases

BioGridi278899. 20 interactions.
MINTiMINT-4667737.

Structurei

3D structure databases

ProteinModelPortaliO13764.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AAA ATPase family.Curated

Phylogenomic databases

InParanoidiO13764.
KOiK13339.
OrthoDBiEOG092C0WBQ.
PhylomeDBiO13764.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR027417. P-loop_NTPase.
IPR015415. Vps4_C.
[Graphical view]
PfamiPF00004. AAA. 2 hits.
PF09336. Vps4_C. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS00674. AAA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O13764-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENRICTLAK PLPKLDESKQ AWVSYLWLKK ALPGFEEHSA YVYMTTNPTI
60 70 80 90 100
AGRIFLPINN EDLEDGTVEI SGYDNLLADA LYISTIAPVK LDFVQLIVID
110 120 130 140 150
DNSQDQDAII ERIKGRNAIL MESDFINQNI LVQVCQPVRH GVVDSETKFV
160 170 180 190 200
IERKDSFTFL ASNEKNISSF KRGKTETDAE LVIRPSKVHT EIQWCLQNCS
210 220 230 240 250
LIHVPFELLF NVGKKNGCPI SLRLSDGKNV YGIASIKSDT EHDSVQLSPS
260 270 280 290 300
LHYFDEFNES VISEEGTEAF LVARGPSVGI ASRISLRTIP TQSCFSEKLL
310 320 330 340 350
KAANLCVVQQ VKQKVFLQSK QIFCVPINSL MANSDSVDIL ELTRNTDAYI
360 370 380 390 400
WYSVEEIDPL NTYNIYYTNE DTSIVLDTQL SHRLLPSLRK PLLNFVKVHP
410 420 430 440 450
PSQKLLRFCR AFFDPQQVPG FNPFFLLHGN PFTGKTKAVE EVASLFSAPV
460 470 480 490 500
FTISSYEFAD ATADHLEAKL DMFVQNVVKS PCAIIFVKDL DVLSISSDEG
510 520 530 540 550
NIVPGSKSIQ ILLSKIDLVK SPQGRYIVIG TCHSIEKIPY EILSESFFEL
560 570 580 590 600
KFSELEMDER LELLKIYANN VIIDKRISLK DVALKTNSMS FGELECLPDH
610 620 630 640 650
MTKAAVDRIK RTGYDNDSII LSGPIITEQD VDVSINRIRK EKSNTIFTVP
660 670 680 690 700
KVNWDDIGGL EEAKTVLRDT LQLPLQFPEL FSQGLKPRSG VLLYGPPGTG
710 720 730 740 750
KTLLAKAVAT ELSLEFVSIK GPELLNMYVG ESEANVRNVF EKARNSSPCV
760 770 780 790 800
IFFDELDSIA PHRGNSSDSG NVMDRVVSQL LAELDSISKD NNKYVFVIGA
810 820 830 840 850
TNRPDLLDPS LLRPGRFDKL VYLGINKSEE SKASMLRALT KTFKLDETID
860 870 880 890 900
LNEIAKNCHP NFTGADMYAL CSDAVLSAIK RKTNEIDLLI QASGTDLSTE
910 920 930 940
EFFKRNENQD SLELRITKED FLTSLKKLRP SISEQELHRY EMVRHQFS
Length:948
Mass (Da):106,506
Last modified:January 1, 1998 - v1
Checksum:iF41DFD7DE6D391B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB11501.1.
PIRiT37816.
RefSeqiNP_593468.1. NM_001018901.2.

Genome annotation databases

EnsemblFungiiSPAC17A5.01.1; SPAC17A5.01.1:pep; SPAC17A5.01.
GeneIDi2542437.
KEGGispo:SPAC17A5.01.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB11501.1.
PIRiT37816.
RefSeqiNP_593468.1. NM_001018901.2.

3D structure databases

ProteinModelPortaliO13764.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi278899. 20 interactions.
MINTiMINT-4667737.

Proteomic databases

MaxQBiO13764.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC17A5.01.1; SPAC17A5.01.1:pep; SPAC17A5.01.
GeneIDi2542437.
KEGGispo:SPAC17A5.01.

Organism-specific databases

EuPathDBiFungiDB:SPAC17A5.01.
PomBaseiSPAC17A5.01. pex6.

Phylogenomic databases

InParanoidiO13764.
KOiK13339.
OrthoDBiEOG092C0WBQ.
PhylomeDBiO13764.

Miscellaneous databases

PROiO13764.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR027417. P-loop_NTPase.
IPR015415. Vps4_C.
[Graphical view]
PfamiPF00004. AAA. 2 hits.
PF09336. Vps4_C. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS00674. AAA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPEX6_SCHPO
AccessioniPrimary (citable) accession number: O13764
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: September 7, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.