Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized Na(+)/H(+) antiporter C15A10.06

Gene

SPAC15A10.06

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Antiport, Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Enzyme and pathway databases

ReactomeiR-SPO-425986. Sodium/Proton exchangers.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized Na(+)/H(+) antiporter C15A10.06
Gene namesi
ORF Names:SPAC15A10.06
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC15A10.06.
PomBaseiSPAC15A10.06.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 3131LumenalSequence analysisAdd
BLAST
Transmembranei32 – 5221HelicalSequence analysisAdd
BLAST
Topological domaini53 – 6412CytoplasmicSequence analysisAdd
BLAST
Transmembranei65 – 8521HelicalSequence analysisAdd
BLAST
Topological domaini86 – 872LumenalSequence analysis
Transmembranei88 – 10821HelicalSequence analysisAdd
BLAST
Topological domaini109 – 12820CytoplasmicSequence analysisAdd
BLAST
Transmembranei129 – 14921HelicalSequence analysisAdd
BLAST
Topological domaini150 – 15910LumenalSequence analysis
Transmembranei160 – 18021HelicalSequence analysisAdd
BLAST
Topological domaini181 – 1888CytoplasmicSequence analysis
Transmembranei189 – 20921HelicalSequence analysisAdd
BLAST
Topological domaini210 – 22718LumenalSequence analysisAdd
BLAST
Transmembranei228 – 24821HelicalSequence analysisAdd
BLAST
Topological domaini249 – 27729CytoplasmicSequence analysisAdd
BLAST
Transmembranei278 – 29821HelicalSequence analysisAdd
BLAST
Topological domaini299 – 31517LumenalSequence analysisAdd
BLAST
Transmembranei316 – 33823HelicalSequence analysisAdd
BLAST
Topological domaini339 – 3479CytoplasmicSequence analysis
Transmembranei348 – 36619HelicalSequence analysisAdd
BLAST
Topological domaini367 – 39226LumenalSequence analysisAdd
BLAST
Transmembranei393 – 41321HelicalSequence analysisAdd
BLAST
Topological domaini414 – 42411CytoplasmicSequence analysisAdd
BLAST
Transmembranei425 – 44521HelicalSequence analysisAdd
BLAST
Topological domaini446 – 567122LumenalSequence analysisAdd
BLAST

GO - Cellular componenti

  • cytoplasm Source: PomBase
  • fungal-type vacuole membrane Source: PomBase
  • Golgi apparatus Source: PomBase
  • Golgi membrane Source: UniProtKB-SubCell
  • integral component of membrane Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 567567Uncharacterized Na(+)/H(+) antiporter C15A10.06PRO_0000317232Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei515 – 5151Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

PTM databases

iPTMnetiO13726.

Interactioni

Protein-protein interaction databases

BioGridi279197. 27 interactions.
MINTiMINT-4667430.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000172307.
InParanoidiO13726.
KOiK12041.
OMAiYYKRSDT.
OrthoDBiEOG092C1Y19.

Family and domain databases

InterProiIPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR004709. NaH_exchanger.
[Graphical view]
PANTHERiPTHR10110. PTHR10110. 2 hits.
PfamiPF00999. Na_H_Exchanger. 1 hit.
[Graphical view]
PRINTSiPR01084. NAHEXCHNGR.
TIGRFAMsiTIGR00840. b_cpa1. 1 hit.

Sequencei

Sequence statusi: Complete.

O13726-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDTILINVF RRDGDDDDDD GQDPALQELY SSWALFILLV LLIGALLTSY
60 70 80 90 100
YVQSKKIRAI HETVISVFVG MVVGLIIRVS PGLIIQNMVS FHSTYFFNVL
110 120 130 140 150
LPPIILNSGY ELHQSNFFRN IGTILTFAFA GTFISAVTLG VLVYIFSFLN
160 170 180 190 200
FENLSMTFVE ALSMGATLSA TDPVTVLAIF NSYKVDQKLY TIIFGESILN
210 220 230 240 250
DAVAIVMFET LQQFQGKTLH FFTLFSGIGI FIITFFISLL IGVSIGLITA
260 270 280 290 300
LLLKYSYLRR YPSIESCIIL LMAYTSYFFS NGCHMSGVVS LLFCGITLKH
310 320 330 340 350
YAFFNMSYKA KLSTKYVFRV LAQLSENFIF IYLGMSLFTQ VDLVYKPIFI
360 370 380 390 400
LITTVAVTAS RYMNVFPLSN LLNKFHRQRN GNLIDHIPYS YQMMLFWAGL
410 420 430 440 450
RGAVGVALAA GFEGENAQTL RATTLVVVVL TLIIFGGTTA RMLEILHIET
460 470 480 490 500
GVAADVDSDT EIGMLPWQQS PEFDLENSAM ELSDASAEPV VVDQQFTTEH
510 520 530 540 550
FDEGNIAPTL SKKVSSTFEQ YQRAAGAFNQ FFHSSRDDQA QWLTRFDEEV
560
IKPVLLERDN LKNGTKK
Length:567
Mass (Da):63,604
Last modified:March 21, 2012 - v3
Checksum:iCBA8F8D2ADAE4D5C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB10103.2.
PIRiT37706.
RefSeqiNP_594293.2. NM_001019716.2.

Genome annotation databases

EnsemblFungiiSPAC15A10.06.1; SPAC15A10.06.1:pep; SPAC15A10.06.
GeneIDi2542747.
KEGGispo:SPAC15A10.06.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB10103.2.
PIRiT37706.
RefSeqiNP_594293.2. NM_001019716.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279197. 27 interactions.
MINTiMINT-4667430.

PTM databases

iPTMnetiO13726.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC15A10.06.1; SPAC15A10.06.1:pep; SPAC15A10.06.
GeneIDi2542747.
KEGGispo:SPAC15A10.06.

Organism-specific databases

EuPathDBiFungiDB:SPAC15A10.06.
PomBaseiSPAC15A10.06.

Phylogenomic databases

HOGENOMiHOG000172307.
InParanoidiO13726.
KOiK12041.
OMAiYYKRSDT.
OrthoDBiEOG092C1Y19.

Enzyme and pathway databases

ReactomeiR-SPO-425986. Sodium/Proton exchangers.

Miscellaneous databases

PROiO13726.

Family and domain databases

InterProiIPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR004709. NaH_exchanger.
[Graphical view]
PANTHERiPTHR10110. PTHR10110. 2 hits.
PfamiPF00999. Na_H_Exchanger. 1 hit.
[Graphical view]
PRINTSiPR01084. NAHEXCHNGR.
TIGRFAMsiTIGR00840. b_cpa1. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYDO6_SCHPO
AccessioniPrimary (citable) accession number: O13726
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: March 21, 2012
Last modified: September 7, 2016
This is version 105 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.