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Protein

Malonyl CoA-acyl carrier protein transacylase, mitochondrial

Gene

mct1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in biosynthesis of fatty acids in mitochondria.By similarity

Catalytic activityi

Malonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier-protein].

Pathwayi: fatty acid biosynthesis

This protein is involved in the pathway fatty acid biosynthesis, which is part of Lipid metabolism.
View all proteins of this organism that are known to be involved in the pathway fatty acid biosynthesis and in Lipid metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase
Biological processFatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

ReactomeiR-SPO-77289 Mitochondrial Fatty Acid Beta-Oxidation
UniPathwayiUPA00094

Names & Taxonomyi

Protein namesi
Recommended name:
Malonyl CoA-acyl carrier protein transacylase, mitochondrial (EC:2.3.1.39)
Short name:
MCT
Alternative name(s):
Malonyl-CoA:ACP transferase
Gene namesi
Name:mct1
ORF Names:SPAC11G7.05c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC11G7.05c
PomBaseiSPAC11G7.05c mct1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000314111? – 318Malonyl CoA-acyl carrier protein transacylase, mitochondrial
Transit peptidei1 – ?MitochondrionSequence analysis

Proteomic databases

MaxQBiO13698
PaxDbiO13698
PRIDEiO13698

Interactioni

Protein-protein interaction databases

BioGridi2781581 interactor.
STRINGi4896.SPAC11G7.05c.1

Structurei

3D structure databases

ProteinModelPortaliO13698
SMRiO13698
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FabD family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

HOGENOMiHOG000036504
InParanoidiO13698
KOiK00645
OMAiAANYNCP
OrthoDBiEOG092C03GO
PhylomeDBiO13698

Family and domain databases

Gene3Di3.40.366.102 hits
InterProiView protein in InterPro
IPR001227 Ac_transferase_dom_sf
IPR014043 Acyl_transferase
IPR016035 Acyl_Trfase/lysoPLipase
IPR016036 Malonyl_transacylase_ACP-bd
IPR020801 PKS_acyl_transferase
PfamiView protein in Pfam
PF00698 Acyl_transf_1, 1 hit
SMARTiView protein in SMART
SM00827 PKS_AT, 1 hit
SUPFAMiSSF52151 SSF52151, 2 hits
SSF55048 SSF55048, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O13698-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAILFPGQG VDWKTWMQPY LENNIVQNTL KEAENVTEIE IRKYIVEAEA
60 70 80 90 100
KSNLRQPITT IAQPAILACS IALLRAFPPF TKKFRFYVGH SLGEYSAFVA
110 120 130 140 150
SQTLSFSSAL KLVQARAKAM SYASALCQNP TSMLAITLTS RFPTDNFLNT
160 170 180 190 200
VYSAVQKYRL IDIANVNSDR QIVLSGDKKE LESITSTLSE LVRSLGKLRS
210 220 230 240 250
NWLDVSGAFH SRYMLPARDS LKNALGETEF NISPELCYTD SGKRFLPIIS
260 270 280 290 300
NVTAELYPAD EEDIRRQLLL QCFRPVLFKN CLKTVKSKYG ANLFYAYGPG
310
TTMQSIAKQN GISTKSRP
Length:318
Mass (Da):35,602
Last modified:January 1, 1998 - v1
Checksum:iC719BA7786333EE0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB16210.1
PIRiT37548
RefSeqiNP_594399.1, NM_001019822.2

Genome annotation databases

EnsemblFungiiSPAC11G7.05c.1; SPAC11G7.05c.1:pep; SPAC11G7.05c
GeneIDi2541662
KEGGispo:SPAC11G7.05c

Similar proteinsi

Entry informationi

Entry nameiFABD_SCHPO
AccessioniPrimary (citable) accession number: O13698
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 1, 1998
Last modified: April 25, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome