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Protein

Uncharacterized RWD, RING finger and WD repeat-containing protein C11E3.05

Gene

SPAC11E3.05

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May be involved in telomere capping.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri1265 – 130945RING-type; degenerateAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized RWD, RING finger and WD repeat-containing protein C11E3.05
Gene namesi
ORF Names:SPAC11E3.05
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC11E3.05.
PomBaseiSPAC11E3.05.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13231323Uncharacterized RWD, RING finger and WD repeat-containing protein C11E3.05PRO_0000310741Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei24 – 241Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO13686.

PTM databases

iPTMnetiO13686.

Structurei

3D structure databases

ProteinModelPortaliO13686.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati271 – 31444WD 1Add
BLAST
Repeati320 – 36041WD 2Add
BLAST
Repeati364 – 40340WD 3Add
BLAST
Repeati409 – 44941WD 4Add
BLAST
Repeati453 – 49442WD 5Add
BLAST
Repeati502 – 55150WD 6Add
BLAST
Domaini671 – 779109RWDPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi159 – 1646Poly-Ser

Sequence similaritiesi

Belongs to the WD repeat WDR59 family.Curated
Contains 1 RING-type zinc finger.Curated
Contains 1 RWD domain.PROSITE-ProRule annotation
Contains 6 WD repeats.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri1265 – 130945RING-type; degenerateAdd
BLAST

Keywords - Domaini

Repeat, WD repeat, Zinc-finger

Phylogenomic databases

InParanoidiO13686.
OMAiDFLWRSR.
OrthoDBiEOG783N3N.
PhylomeDBiO13686.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR006575. RWD-domain.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
SMARTiSM00591. RWD. 1 hit.
SM00320. WD40. 4 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS50908. RWD. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O13686-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRELQGDDSS RKSPPSDSVV KNSSPIDYEH SLKSLQDERT LNYPNKQFNS
60 70 80 90 100
ENPSSYYNMD DSGELCNFEL EKDSLESMIH ESSTALSAQS NTAQDGDQLA
110 120 130 140 150
SSSTISKDHS ETLDNKLNDS KILIKKASNS FANFSESVRS STIVAYSQTP
160 170 180 190 200
TQRLQGLTSI SSSSFDDGSY GSRRISFNSQ GVSGRLRRNM DSTVIIPSED
210 220 230 240 250
EDLQLPSNSN SNVEYGPFDS TTFDRQLSIE VNQPVGAMSL SPCGRDIALA
260 270 280 290 300
SRYGLLVLDL DNPYNPPRML RHSTPWEVAD TQWNVHAARD QWVVSTSSQK
310 320 330 340 350
TIVWNLALPN DRAIEFMLHG HTRAVTDMNW HRQNPDVLAT CSIDSSVHCW
360 370 380 390 400
DLRSPRFPVN SFYDWHNGAT QVKWNYKNPH ILASSHGRLV RIWDDRYGSA
410 420 430 440 450
PLHTIKTSEN ITKINGLEFN RACETRLLTC AMDRTVKFWN YEKSTEEPEH
460 470 480 490 500
LITTDSPVWK ARFTPFGDGV ILMPQRGDNS VHMYDCRNLD KEGPRAVHRF
510 520 530 540 550
AGHTDQVKEF LWRCRGEDVF DRDLRDFQLI TWSKDHHVRL WPIGNDILNS
560 570 580 590 600
MGHDRTKPVP FKLTRLGAKY RTYSREPLKQ SLINTECDSS DAMNSFDSNF
610 620 630 640 650
GAERANTSDL SRGFVAFANR KKSKYNLPGS SGFMTRSTKS TNPMTPLNWL
660 670 680 690 700
RGISMGRLGN ADWEVPQNLG EELSWIGQKY SNVSFEKIDV AERTCTISLN
710 720 730 740 750
APILPDDGYA YIRLHVYFPN NYPISATPVF QLERSSAFND EQFNYVFNTL
760 770 780 790 800
TSISDQCISS HKYCMDACLS YLSGNLSVDE IWKLGFQKDN SDSSSESSAD
810 820 830 840 850
IFQDVFPSMP DFRGGDRGLS HKHQNIPLPK TCAAIFCGND ELVCFFTIKA
860 870 880 890 900
DESAAQATAN RETHGRQKLF ESFGVLDSSN SVADSDSTNY DDENSLNRGG
910 920 930 940 950
TSESDSEFIW DVDESNSGSI VFPKSKTSIN LNNINSASAS IMGSRFGAAD
960 970 980 990 1000
IFMSKRPSTK GSNRPSILLS KPSHDFHVVR IISMSKYLPV KRALAAEYVV
1010 1020 1030 1040 1050
DTGDKVTVCN KNAEVSAKHN YYRLAKVWLM LGRLLGHLSR TENKDHINDE
1060 1070 1080 1090 1100
EAFPWLKSPL AKWVVNSLLD YYASQCNTQM LAMLACVLDI PNPKKQSGNT
1110 1120 1130 1140 1150
SADQVLFNQP KQVTEKLGVQ LNLPKTKILE KVSSHSLAQI TALREKEPKD
1160 1170 1180 1190 1200
ADSTYSKEKI FSATSTVHLQ LMDYDKQNND FVDAQEIAYT KLLQQKFIQW
1210 1220 1230 1240 1250
RATYAEQLDL WGFFIPKLEM LKFNAHEFSS PSEKTLVNHC NSCNSTTSNT
1260 1270 1280 1290 1300
RICEKCYSLV PRMSCTFCCL SIHGLCIVCG LCLHVMHEDC YKEWFSNGDS
1310 1320
ISQSCSSGCG CKCQFQHMSL EKV
Length:1,323
Mass (Da):149,063
Last modified:January 1, 1998 - v1
Checksum:i610D4590AA78BF69
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB11184.1.
PIRiT37533.
RefSeqiNP_594930.1. NM_001020361.2.

Genome annotation databases

EnsemblFungiiSPAC11E3.05.1; SPAC11E3.05.1:pep; SPAC11E3.05.
GeneIDi2541877.
KEGGispo:SPAC11E3.05.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB11184.1.
PIRiT37533.
RefSeqiNP_594930.1. NM_001020361.2.

3D structure databases

ProteinModelPortaliO13686.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiO13686.

Proteomic databases

MaxQBiO13686.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC11E3.05.1; SPAC11E3.05.1:pep; SPAC11E3.05.
GeneIDi2541877.
KEGGispo:SPAC11E3.05.

Organism-specific databases

EuPathDBiFungiDB:SPAC11E3.05.
PomBaseiSPAC11E3.05.

Phylogenomic databases

InParanoidiO13686.
OMAiDFLWRSR.
OrthoDBiEOG783N3N.
PhylomeDBiO13686.

Miscellaneous databases

PROiO13686.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR006575. RWD-domain.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
SMARTiSM00591. RWD. 1 hit.
SM00320. WD40. 4 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS50908. RWD. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-24, IDENTIFICATION BY MASS SPECTROMETRY.

Entry informationi

Entry nameiWDR59_SCHPO
AccessioniPrimary (citable) accession number: O13686
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: January 1, 1998
Last modified: June 8, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.