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Protein

60S ribosomal protein L8

Gene

rpl8

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-SPO-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-SPO-1799339 SRP-dependent cotranslational protein targeting to membrane
R-SPO-72689 Formation of a pool of free 40S subunits
R-SPO-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-SPO-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-SPO-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L8
Alternative name(s):
L4
L7A
Gene namesi
Name:rpl8
ORF Names:SPBC29A3.04
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC29A3.04
PomBaseiSPBC29A3.04 rpl8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001367592 – 25960S ribosomal protein L8Add BLAST258

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei11Phosphoserine1 Publication1
Modified residuei33Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO13672
PaxDbiO13672
PRIDEiO13672

PTM databases

iPTMnetiO13672

Interactioni

Protein-protein interaction databases

BioGridi277045, 9 interactors
IntActiO13672, 4 interactors
MINTiO13672
STRINGi4896.SPBC29A3.04.1

Structurei

3D structure databases

ProteinModelPortaliO13672
SMRiO13672
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000216644
InParanoidiO13672
KOiK02936
OMAiRSFGIGQ
OrthoDBiEOG092C4PDY
PhylomeDBiO13672

Family and domain databases

Gene3Di3.30.1330.210, 1 hit
InterProiView protein in InterPro
IPR029064 L30e-like
IPR001921 Ribosomal_L7A/L8
IPR038524 Ribosomal_L7A/L8_sf
IPR004038 Ribosomal_L7Ae/L30e/S12e/Gad45
IPR018492 Ribosomal_L7Ae/L8/Nhp2
IPR004037 Ribosomal_L7Ae_CS
PfamiView protein in Pfam
PF01248 Ribosomal_L7Ae, 1 hit
PRINTSiPR00881 L7ARS6FAMILY
PR00882 RIBOSOMALL7A
SUPFAMiSSF55315 SSF55315, 1 hit
PROSITEiView protein in PROSITE
PS01082 RIBOSOMAL_L7AE, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O13672-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPKSKKVAP SPFAQPKAAK TTKNPLFVSR PRSFGIGQDI QPKRDLSRFV
60 70 80 90 100
KWPEYIRLQR RRKILNLRLK VPPAIAQFQK TLDKNTATQV FKLLNKYRPE
110 120 130 140 150
TAAEKKQRLV AEAEAVANGK SAQDVSKKPY NVKYGLNHVV ALIEAKKAKL
160 170 180 190 200
VLIASDVDPI ELVVFLPALC KKMGVPYAIV KNKARLGTVI HQKTAAVLAV
210 220 230 240 250
TEVREEDKNE LASIVSAVDA NFSAKYDESR RKWGGGIMGG KTQALLAKRA

KAAAATVRL
Length:259
Mass (Da):28,607
Last modified:January 23, 2007 - v3
Checksum:iA37A4873E4A2A798
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ001133 Genomic DNA Translation: CAA04548.1
CU329671 Genomic DNA Translation: CAA18381.1
AB005750 mRNA Translation: BAA21551.1
PIRiT40075
RefSeqiNP_595832.1, NM_001021736.2

Genome annotation databases

EnsemblFungiiSPBC29A3.04.1; SPBC29A3.04.1:pep; SPBC29A3.04
GeneIDi2540517
KEGGispo:SPBC29A3.04

Similar proteinsi

Entry informationi

Entry nameiRL8_SCHPO
AccessioniPrimary (citable) accession number: O13672
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 128 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health