O13640 (YGWH_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized alpha-1,2-galactosyltransferase C8D2.17
EC=2.4.1.-

Gene names

ORF Names:

SPBC8D2.17, pi048

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Taxonomic identifier

284812 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length	328 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Endoplasmic reticulum Ref.3.
Sequence similarities	Belongs to the glycosyltransferase 34 family.
Sequence caution	The sequence BAA21428.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Cellular component	Endoplasmic reticulum
Domain	Signal
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	fungal-type cell wall biogenesis Inferred from sequence or structural similarity. Source: GeneDB_Spombe protein galactosylation Inferred from sequence or structural similarity. Source: GeneDB_Spombe
Cellular component	Golgi membrane Inferred from sequence or structural similarity. Source: GeneDB_Spombe endoplasmic reticulum Inferred from direct assay. Source: GeneDB_Spombe integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular function	alpha-1,2-galactosyltransferase activity Inferred from sequence or structural similarity. Source: GeneDB_Spombe
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 32	32	Potential
	Chain	33 – 328	296	Uncharacterized alpha-1,2-galactosyltransferase C8D2.17		PRO_0000339339
Regions
	Compositional bias	28 – 86	59	Ser-rich

Sequences

	Sequence		Length	Mass (Da)
	O13640 [UniParc]. Last modified September 22, 2009. Version 2. Checksum: C8419858A4BF443E	FASTA	328	36,998
	10 20 30 40 50 60 MFNFRLFSRR GKSLGLLAIV LLLFGFYSLK SSMPVYSNSI GSPSAHSSSY KGVSKAKTSP 70 80 90 100 110 120 QDPDSVVMLI VSFDDHYDSS RSDSSSVFLD KVLSDRTEYA LRHGYTLVHK KARDIQARYG 130 140 150 160 170 180 VYGTWSIIPA LRETLAEYPD AGWIWLLDAK AVIMNPSESL KDRVLKPEKL SQHLLLNSPI 190 200 210 220 230 240 DPLKNYIRTR RKMDPSDVFV ITTSDYNGIS TRSLLIKNNN FAPFLLDAWN EPLLKSAGFD 250 260 270 280 290 300 QAERSALSHL LEAHNTILDH VALVSPKVLN SYTNSAVDLN YEEGDFLVIL QDCENAAACE 310 320 RIFDNYYQQR KLPAIKKQLS EETVDEQS

References

[1]	"A 38 kb segment containing the cdc2 gene from the left arm of fission yeast chromosome II: sequence analysis and characterization of the genomic DNA and cDNAs encoded on the segment." Machida M., Yamazaki S., Kunihiro S., Tanaka T., Kushida N., Jinno K., Haikawa Y., Yamazaki J., Yamamoto S., Sekine M., Oguchi A., Nagai Y., Sakai M., Aoki K., Ogura K., Kudoh Y., Kikuchi H., Zhang M.Q., Yanagida M. Yeast 16:71-80(2000) [PubMed: 10620777] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843.
[2]	"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843.
[3]	"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe." Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M. Nat. Biotechnol. 24:841-847(2006) [PubMed: 16823372] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB004537 Genomic DNA. Translation: BAA21428.1. Sequence problems. CU329671 Genomic DNA. Translation: CAA17832.2.
PIR	T40762.
RefSeq	NP_595579.2. NM_001021474.2.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	O13640.
Protein family/group databases
CAZy	GT34. Glycosyltransferase Family 34.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	SPBC8D2.17.1; SPBC8D2.17.1:pep; SPBC8D2.17.
GeneID	2541250.
KEGG	spo:SPBC8D2.17.
NMPDR	fig|4896.1.peg.1445.
Organism-specific databases
GeneDB_Spombe	SPBC8D2.17.
Phylogenomic databases
eggNOG	fuNOG08674.
GeneTree	EFGT00050000004280.
OMA	LEHIVQW.
OrthoDB	EOG46T69N.
Gene expression databases
ArrayExpress	O13640.
Family and domain databases
InterPro	IPR008630. Glyco_trans_34. [Graphical view]
KO	K05532.
Pfam	PF05637. Glyco_transf_34. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YGWH_SCHPO

Accession

Primary (citable) accession number: O13640

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	September 22, 2009
Last modified:	December 14, 2011
This is version 60 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program