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Protein

Multiple RNA-binding domain-containing protein 1

Gene

mrd1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in pre-rRNA processing.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Multiple RNA-binding domain-containing protein 1
Gene namesi
Name:mrd1
ORF Names:pi029, SPBP22H7.02c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBP22H7.02c.
PomBaseiSPBP22H7.02c. mrd1.

Subcellular locationi

GO - Cellular componenti

  • 90S preribosome Source: PomBase
  • nucleolus Source: PomBase
  • nucleus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000816441 – 833Multiple RNA-binding domain-containing protein 1Add BLAST833

Proteomic databases

MaxQBiO13620.
PRIDEiO13620.

Interactioni

Protein-protein interaction databases

BioGridi277815. 1 interactor.
MINTiMINT-4666788.

Structurei

3D structure databases

ProteinModelPortaliO13620.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 83RRM 1PROSITE-ProRule annotationAdd BLAST82
Domaini323 – 401RRM 2PROSITE-ProRule annotationAdd BLAST79
Domaini506 – 578RRM 3PROSITE-ProRule annotationAdd BLAST73
Domaini619 – 702RRM 4PROSITE-ProRule annotationAdd BLAST84
Domaini721 – 798RRM 5PROSITE-ProRule annotationAdd BLAST78

Sequence similaritiesi

Belongs to the RRM MRD1 family.Curated
Contains 5 RRM (RNA recognition motif) domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

HOGENOMiHOG000211156.
InParanoidiO13620.
KOiK14787.
OMAiYRSANEK.
OrthoDBiEOG092C1UL3.
PhylomeDBiO13620.

Family and domain databases

Gene3Di3.30.70.330. 5 hits.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 5 hits.
[Graphical view]
SMARTiSM00360. RRM. 5 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 4 hits.
PROSITEiPS50102. RRM. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O13620-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRIIIKNIP RYYDKEKLST YLKSLPQLDA EITDVSVAKT KEGVSRRFAF
60 70 80 90 100
IGFKNEEDAD KAIRYLNKSY VETSRIEVHR ALDYRSANEK LRPYSKYASK
110 120 130 140 150
NIELKLQKKE KEEELRNLEE EKAKKKKDAN LKRKFLDTLD PKAREFLKLS
160 170 180 190 200
SSISNSRSWE NEEVFDTEIT NPVIPADEDD DEYQDLPAAK RHEGDSIKST
210 220 230 240 250
EHDSTLDSGV VIDGREKSSS ELHEEESEQA AEGDTAKNSG TDAQAPLSDD
260 270 280 290 300
EWLRLHRTRI KEKQPEEEVS VVGDELKSFD KENNDEHLER VTNDKIADAS
310 320 330 340 350
MLQKAENNVS EQERNIQLIS ETKRLFLRNL TYSCAEDDLK SLFGPFGQLE
360 370 380 390 400
QVHMPIDKKT NNPKGFAYID FHDADDAVRA YLELDAKPFQ GRLLHVLPAK
410 420 430 440 450
ARSSILLDDY ALSKLPLKKQ RELKRKNTAA SSTFSWNSLY MNADAVVTSL
460 470 480 490 500
ASRLGVKKTD ILDPTSSDSA VKQALTETHV IQETKNFFEE HGVDLDAFKN
510 520 530 540 550
AARSDNVLLV KNFPYGTSAE ELTSLFSPFG ELGRILIPPA GTIAIIEFLN
560 570 580 590 600
APDCRQAFSK LAYTRIKSSI LYLEKAPRDV FTTSFKQSGK PELAQKVNAV
610 620 630 640 650
EATTSEKVGT EDIESLDTAT IYVKNLNFST KQEEFQKVFK PLEGYLSAVI
660 670 680 690 700
RAKPDPKRPG KYLSMGFGFV EFKDKASAVA AMHAMNGFVL DGHKLEIKLS
710 720 730 740 750
HQGVDAAAEV RKQDSSKPKG TKILIKNLPF EATKKDVQSL LGAYGQLRSV
760 770 780 790 800
RVPKKFDRSA RGFAFAEFVT AREAANAMRA LKNTHLLGRH LVLQYASNAT
810 820 830
MDDMQHAIEK MAKEANAEAA APSITGKRLI ETD
Length:833
Mass (Da):93,677
Last modified:January 1, 1998 - v1
Checksum:i64FE767D43E02FE4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB004535 Genomic DNA. Translation: BAA21408.1.
CU329671 Genomic DNA. Translation: CAC37370.1.
AB028003 Genomic DNA. Translation: BAA87307.1.
RefSeqiNP_595599.1. NM_001021494.2.

Genome annotation databases

EnsemblFungiiSPBP22H7.02c.1; SPBP22H7.02c.1:pep; SPBP22H7.02c.
GeneIDi2541303.
KEGGispo:SPBP22H7.02c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB004535 Genomic DNA. Translation: BAA21408.1.
CU329671 Genomic DNA. Translation: CAC37370.1.
AB028003 Genomic DNA. Translation: BAA87307.1.
RefSeqiNP_595599.1. NM_001021494.2.

3D structure databases

ProteinModelPortaliO13620.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277815. 1 interactor.
MINTiMINT-4666788.

Proteomic databases

MaxQBiO13620.
PRIDEiO13620.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBP22H7.02c.1; SPBP22H7.02c.1:pep; SPBP22H7.02c.
GeneIDi2541303.
KEGGispo:SPBP22H7.02c.

Organism-specific databases

EuPathDBiFungiDB:SPBP22H7.02c.
PomBaseiSPBP22H7.02c. mrd1.

Phylogenomic databases

HOGENOMiHOG000211156.
InParanoidiO13620.
KOiK14787.
OMAiYRSANEK.
OrthoDBiEOG092C1UL3.
PhylomeDBiO13620.

Miscellaneous databases

PROiO13620.

Family and domain databases

Gene3Di3.30.70.330. 5 hits.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 5 hits.
[Graphical view]
SMARTiSM00360. RRM. 5 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 4 hits.
PROSITEiPS50102. RRM. 5 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMRD1_SCHPO
AccessioniPrimary (citable) accession number: O13620
Secondary accession number(s): Q9UTU1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: January 1, 1998
Last modified: November 30, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.