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Protein

Meiosis-specific transcription factor mei4

Gene

mei4

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Functions as a meiosis-specific transcription factor. Binds to the 5'-GTAAAYA-3' consensus sequence of the promoter of the spo6 gene.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi81 – 172Fork-headPROSITE-ProRule annotationAdd BLAST92

GO - Molecular functioni

GO - Biological processi

  • anatomical structure morphogenesis Source: GO_Central
  • cell differentiation Source: GO_Central
  • positive regulation of reciprocal meiotic recombination Source: PomBase
  • positive regulation of transcription by RNA polymerase II Source: PomBase
  • positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle Source: PomBase
  • regulation of meiotic cell cycle Source: PomBase
  • regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle Source: PomBase

Keywordsi

Molecular functionActivator, DNA-binding
Biological processMeiosis, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Meiosis-specific transcription factor mei4
Gene namesi
Name:mei4
ORF Names:pi013, SPBC32H8.11
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi

Organism-specific databases

EuPathDBiFungiDB:SPBC32H8.11
PomBaseiSPBC32H8.11 mei4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000919061 – 517Meiosis-specific transcription factor mei4Add BLAST517

Proteomic databases

PaxDbiO13606
PRIDEiO13606

PTM databases

iPTMnetiO13606

Interactioni

Protein-protein interaction databases

BioGridi276773, 27 interactors
DIPiDIP-59802N
IntActiO13606, 3 interactors
STRINGi4896.SPBC32H8.11.1

Structurei

3D structure databases

ProteinModelPortaliO13606
SMRiO13606
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

InParanoidiO13606
OrthoDBiEOG092C0D3W

Family and domain databases

CDDicd00059 FH, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR001766 Fork_head_dom
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00250 Forkhead, 1 hit
PRINTSiPR00053 FORKHEAD
SMARTiView protein in SMART
SM00339 FH, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00658 FORK_HEAD_2, 1 hit
PS50039 FORK_HEAD_3, 1 hit

Sequencei

Sequence statusi: Complete.

O13606-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVENQGNVEA HGKPKKVILS LSLKESSKIN DSQNVSNVSS KEKCETEALL
60 70 80 90 100
REENKENLSS DSIRQMIFGD EMAGFVDTGE KPPCSYATLI GLAILQSHNK
110 120 130 140 150
QLTLSGIYTW IRNTFRYYLN HDGGWQNSIR HNLSLNKAFI KVEKPKGKTL
160 170 180 190 200
KGHYWTIDPD HMQNFVSVRL HRSHSTDSNS KKRPSSKCHE IKPLTTREIP
210 220 230 240 250
LARKRSRLNS FNSSTSTSGS SSNVAAEVSN DASQPSNQDS SLNSNIVKPP
260 270 280 290 300
LPPSNVQSNS SSSENVPKPN AETQEDLPTI DAHESSLYEN VNDSRLYEVP
310 320 330 340 350
ACRNMALNTG YSDADPGYLR TSFRSNSHNS LPYSANEEED VLQADFLVSQ
360 370 380 390 400
QSSMVSSYVS SRDPHSMPYY RREPIPLRPS SRFYEYTRPT YGRTDTSCSA
410 420 430 440 450
PGAFCSTQIN SPSSYINYSK CAPSSPTLSL QKHREHVKSL LYVPDLTPSF
460 470 480 490 500
DGSDPWNPSS QLLSEPLFDQ HSFQSSLDDL MSVTCFRDSP ELNHESSGYS
510
SAPLMPSNRA FINDFSL
Length:517
Mass (Da):57,685
Last modified:January 1, 1998 - v1
Checksum:i05D912F04525C759
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB012695 Genomic DNA Translation: BAA25402.1
AB004534 Genomic DNA Translation: BAA21390.1
CU329671 Genomic DNA Translation: CAC37501.1
PIRiT43358
RefSeqiNP_595617.1, NM_001021512.2

Genome annotation databases

EnsemblFungiiSPBC32H8.11.1; SPBC32H8.11.1:pep; SPBC32H8.11
GeneIDi2540241
KEGGispo:SPBC32H8.11

Entry informationi

Entry nameiMEI4_SCHPO
AccessioniPrimary (citable) accession number: O13606
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names

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