O13554 (VPS65_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative uncharacterized protein VPS65

Gene names

Name:	VPS65
Ordered Locus Names:	YLR322W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	104 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Function	Deletion causes a vacuolar protein sorting defect.
Subcellular location	Membrane; Multi-pass membrane protein Potential.
Caution	Product of a dubious gene prediction. Partially overlaps SFH1.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 104	104	Putative uncharacterized protein VPS65		PRO_0000299781
Regions
	Transmembrane	4 – 24	21	Helical; Potential
	Transmembrane	80 – 100	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	O13554 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: A68FCABB5AB6F807	FASTA	104	12,162
	10 20 30 40 50 60 MRHCIIFIVC ISIVEIRTVH IEFIKEIVVI FRIVDHFSPF MLPCLLSHCK DGDTIIFVCQ 70 80 90 100 SVMKVRNISL WNKLVLVRHC VLLCAFLLSF FNVLHSIISI CRIF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XII." Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H. , Hilger F., Kleine K., Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., Hani J., Hoheisel J.D. Nature 387:87-90(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae." Bonangelino C.J., Chavez E.M., Bonifacino J.S. Mol. Biol. Cell 13:2486-2501(2002) [PubMed] [Europe PMC] [Abstract] Cited for: EFFECT OF GENE DELETION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U20618 Genomic DNA. Translation: AAB64531.1.
PIR	S69310.
3D structure databases
ProteinModelPortal	O13554.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-1902N.
IntAct	O13554. 1 interaction.
MINT	MINT-408044.
STRING	4932.YLR322W.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YLR322W; YLR322W; YLR322W.
Organism-specific databases
SGD	S000004314. VPS65.
Gene expression databases
Genevestigator	O13554.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

VPS65_YEAST

Accession

Primary (citable) accession number: O13554

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	January 1, 1998
Last modified:	April 3, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program