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O13554 (VPS65_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative uncharacterized protein VPS65
Gene names
Name:VPS65
Ordered Locus Names:YLR322W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length104 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Function

Deletion causes a vacuolar protein sorting defect.

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Caution

Product of a dubious gene prediction. Partially overlaps SFH1.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 104104Putative uncharacterized protein VPS65
PRO_0000299781

Regions

Transmembrane4 – 2421Helical; Potential
Transmembrane80 – 10021Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
O13554 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: A68FCABB5AB6F807

FASTA10412,162
        10         20         30         40         50         60 
MRHCIIFIVC ISIVEIRTVH IEFIKEIVVI FRIVDHFSPF MLPCLLSHCK DGDTIIFVCQ 

        70         80         90        100 
SVMKVRNISL WNKLVLVRHC VLLCAFLLSF FNVLHSIISI CRIF 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XII."
Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H. expand/collapse author list , Hilger F., Kleine K., Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., Hani J., Hoheisel J.D.
Nature 387:87-90(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae."
Bonangelino C.J., Chavez E.M., Bonifacino J.S.
Mol. Biol. Cell 13:2486-2501(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: EFFECT OF GENE DELETION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U20618 Genomic DNA. Translation: AAB64531.1.
BK006945 Genomic DNA. No translation available.
PIRS69310.

3D structure databases

ProteinModelPortalO13554.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-1902N.
IntActO13554. 1 interaction.
MINTMINT-408044.
STRING4932.YLR322W.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYLR322W; YLR322W; YLR322W.

Organism-specific databases

SGDS000004314. VPS65.

Phylogenomic databases

OMACISIVEI.
OrthoDBEOG7CNZX0.

Gene expression databases

GenevestigatorO13554.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameVPS65_YEAST
AccessionPrimary (citable) accession number: O13554
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: January 1, 1998
Last modified: May 14, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XII

Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD