Reviewed, UniProtKB/Swiss-Prot O13529 (ECM12_YEAST)

Names and origin

Protein names

Recommended name:
    Protein ECM12
Alternative name(s):
    Extracellular mutant protein 12

Gene names

Name:	ECM12
Ordered Locus Names:	YHR021W-A

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	151 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	May be involved in cell wall organization and biogenesis.
Subcellular location	Membrane; Multi-pass membrane protein Potential.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Cellular component	Membrane
Domain	Transmembrane
PTM	Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell wall organization Ref.2 Inferred from mutant phenotype. Source: SGD
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 151	151	Protein ECM12		PRO_0000239641
Regions
	Transmembrane	17 – 37	21	Potential
	Transmembrane	51 – 71	21	Potential
Amino acid modifications
	Glycosylation	2	1	N-linked (GlcNAc...) Potential
	Glycosylation	132	1	N-linked (GlcNAc...) Potential
	Glycosylation	137	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	O13529-1 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 8F36494519BE7DF0	FASTA	151	17,435
	10 20 30 40 50 60 MNRSFHFLIK YIYIHVLLVF YFHIKQQAIM PFFIFFFSSF DGLSFDLRVV AFLAKHVFVG 70 80 90 100 110 120 VCSPFFVVGF FGSSRVVVTE WLSKLVLPPP PVSITQVFSL SRKRGEFSSG YILIINPYKS 130 140 150 FLRSLLDFSI FNNTAKNKSS TFTLNLEDVS K

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M. Science 265:2077-2082(1994) [PubMed: 8091229] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae." Lussier M., White A.-M., Sheraton J., di Paolo T., Treadwell J., Southard S.B., Horenstein C.I., Chen-Weiner J., Ram A.F.J., Kapteyn J.C., Roemer T.W., Vo D.H., Bondoc D.C., Hall J., Zhong W.-W., Sdicu A.-M., Davies J., Klis F.M., Robbins P.W., Bussey H. Genetics 147:435-450(1997) [PubMed: 9335584] [Abstract] Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U10399 Genomic DNA. Translation: AAB68882.1.
PIR	S52598.
RefSeq	NP_011886.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	O13529. 4 interactions.
Genome annotation databases
Ensembl	YHR021W-A; YHR021W-A; YHR021W-A; Saccharomyces cerevisiae. [Genome view]
GeneID	856416.
KEGG	sce:YHR021W-A.
NMPDR	fig|4932.3.peg.3031.
Organism-specific databases
CYGD	YHR021w-a.
SGD	S000003531. ECM12.
Phylogenomic databases
OrthoDB	EOG970W0G
Gene expression databases
ArrayExpress	O13529.
Genevestigator	O13529.
GermOnline	YHR021W-A. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other Resources
NextBio	981976.

Entry information

Entry name

ECM12_YEAST

Accession

Primary (citable) accession number: O13529

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 13, 2006
Last sequence update:	January 1, 1998
Last modified:	November 24, 2009
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)