O13529 (ECM12_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein ECM12

Alternative name(s):
Extracellular mutant protein 12

Gene names

Name:	ECM12
Ordered Locus Names:	YHR021W-A

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	151 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	May be involved in cell wall organization and biogenesis.
Subcellular location	Membrane; Multi-pass membrane protein Potential.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	fungal-type cell wall organization Inferred from mutant phenotype Ref.3. Source: SGD
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 151	151	Protein ECM12		PRO_0000239641
Regions
	Transmembrane	17 – 37	21	Helical; Potential
	Transmembrane	51 – 71	21	Helical; Potential
Amino acid modifications
	Glycosylation	2	1	N-linked (GlcNAc...) Potential
	Glycosylation	132	1	N-linked (GlcNAc...) Potential
	Glycosylation	137	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	O13529 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 8F36494519BE7DF0	FASTA	151	17,435
	10 20 30 40 50 60 MNRSFHFLIK YIYIHVLLVF YFHIKQQAIM PFFIFFFSSF DGLSFDLRVV AFLAKHVFVG 70 80 90 100 110 120 VCSPFFVVGF FGSSRVVVTE WLSKLVLPPP PVSITQVFSL SRKRGEFSSG YILIINPYKS 130 140 150 FLRSLLDFSI FNNTAKNKSS TFTLNLEDVS K

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M. Science 265:2077-2082(1994) [PubMed: 8091229] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae." Lussier M., White A.-M., Sheraton J., di Paolo T., Treadwell J., Southard S.B., Horenstein C.I., Chen-Weiner J., Ram A.F.J., Kapteyn J.C., Roemer T.W., Vo D.H., Bondoc D.C., Hall J., Zhong W.-W., Sdicu A.-M., Davies J., Klis F.M., Robbins P.W., Bussey H. Genetics 147:435-450(1997) [PubMed: 9335584] [Abstract] Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U10399 Genomic DNA. Translation: AAB68882.1. BK006934 Genomic DNA. Translation: DAA06711.1.
PIR	S52598.
RefSeq	NP_011886.1. NM_001181428.1.
3D structure databases
ProteinModelPortal	O13529.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YHR021W-A; YHR021W-A; YHR021W-A.
GeneID	856416.
KEGG	sce:YHR021W-A.
NMPDR	fig|4932.3.peg.3031.
Organism-specific databases
CYGD	YHR021w-a.
SGD	S000003531. ECM12.
Gene expression databases
ArrayExpress	O13529.
Genevestigator	O13529.
GermOnline	YHR021W-A. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other
NextBio	981976.

Entry information

Entry name

ECM12_YEAST

Accession

Primary (citable) accession number: O13529
Secondary accession number(s): D3DKW7

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 13, 2006
Last sequence update:	January 1, 1998
Last modified:	September 21, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program