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O13504

- TRPF_PICPA

UniProt

O13504 - TRPF_PICPA

Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

TRP1

Organism
Komagataella pastoris (Yeast) (Pichia pastoris)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.

    Pathwayi

    GO - Molecular functioni

    1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00035; UER00042.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
    Short name:
    PRAI
    Gene namesi
    Name:TRP1
    OrganismiKomagataella pastoris (Yeast) (Pichia pastoris)
    Taxonomic identifieri4922 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKomagataella

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 237237N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154335Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliO13504.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpF family.Curated

    Family and domain databases

    Gene3Di3.20.20.70. 2 hits.
    HAMAPiMF_00135. PRAI.
    InterProiIPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00697. PRAI. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    O13504-1 [UniParc]FASTAAdd to Basket

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    MALVKICGLQ SLEAAETAVN NGASLVGVIM VPGRERTVKQ EVAREISQMV    50
    REKRISKGSK YLDSRQLRKE WDDCPLEDWF EYNVKEINSS GPFLVGVFRN 100
    QSIDEIQQAI HTHGLDFVQL HGSEDFDSYI RNIPVPVITR YTDNAVDGLT 150
    GEDLAINRAL VLLDSEQGGE GKTIDWARAQ KFGERRGKYL LAGGVTPDNV 200
    AHARSHTGCI GVDVSGGVET NASKDMDKIT QFIRNAT 237
    Length:237
    Mass (Da):26,177
    Last modified:January 1, 1998 - v1
    Checksum:i448F67284E028570
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ001000 Genomic DNA. Translation: CAA04452.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ001000 Genomic DNA. Translation: CAA04452.1 .

    3D structure databases

    ProteinModelPortali O13504.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00042 .

    Family and domain databases

    Gene3Di 3.20.20.70. 2 hits.
    HAMAPi MF_00135. PRAI.
    InterProi IPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00697. PRAI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and sequence analysis of the Pichia pastoris TRP1, IPP1 and HIS3 genes."
      Cosano I.C., Alvarez P., Molina M., Nombela C.
      Yeast 14:861-867(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: NRRL Y-11430.

    Entry informationi

    Entry nameiTRPF_PICPA
    AccessioniPrimary (citable) accession number: O13504
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3