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O13504

- TRPF_PICPA

UniProt

O13504 - TRPF_PICPA

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Protein
N-(5'-phosphoribosyl)anthranilate isomerase
Gene
TRP1
Organism
Komagataella pastoris (Yeast) (Pichia pastoris)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:TRP1
OrganismiKomagataella pastoris (Yeast) (Pichia pastoris)
Taxonomic identifieri4922 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKomagataella

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 237237N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation
PRO_0000154335Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO13504.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Family and domain databases

Gene3Di3.20.20.70. 2 hits.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 2 hits.

Sequencei

Sequence statusi: Complete.

O13504-1 [UniParc]FASTAAdd to Basket

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MALVKICGLQ SLEAAETAVN NGASLVGVIM VPGRERTVKQ EVAREISQMV    50
REKRISKGSK YLDSRQLRKE WDDCPLEDWF EYNVKEINSS GPFLVGVFRN 100
QSIDEIQQAI HTHGLDFVQL HGSEDFDSYI RNIPVPVITR YTDNAVDGLT 150
GEDLAINRAL VLLDSEQGGE GKTIDWARAQ KFGERRGKYL LAGGVTPDNV 200
AHARSHTGCI GVDVSGGVET NASKDMDKIT QFIRNAT 237
Length:237
Mass (Da):26,177
Last modified:January 1, 1998 - v1
Checksum:i448F67284E028570
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ001000 Genomic DNA. Translation: CAA04452.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ001000 Genomic DNA. Translation: CAA04452.1 .

3D structure databases

ProteinModelPortali O13504.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .

Family and domain databases

Gene3Di 3.20.20.70. 2 hits.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 2 hits.
ProtoNeti Search...

Publicationsi

  1. "Cloning and sequence analysis of the Pichia pastoris TRP1, IPP1 and HIS3 genes."
    Cosano I.C., Alvarez P., Molina M., Nombela C.
    Yeast 14:861-867(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: NRRL Y-11430.

Entry informationi

Entry nameiTRPF_PICPA
AccessioniPrimary (citable) accession number: O13504
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 1, 1998
Last modified: February 19, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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