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Reviewed, UniProtKB/Swiss-Prot O13353 (CHS4_MAGGR)

Last modified November 3, 2009. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Chitin synthase 4
    EC=2.4.1.16
Alternative name(s):
    Chitin-UDP acetyl-glucosaminyl transferase 4
    Class-IV chitin synthase 4
Gene names
Name: CHS4
ORF Names: MGG_09962
OrganismMagnaporthe grisea (Rice blast fungus) (Pyricularia grisea) [Complete proteome]
Taxonomic identifier148305 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeMagnaporthalesMagnaporthaceaeMagnaporthe

Protein attributes

Sequence length1229 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Plays a major role in cell wall biogenesis.

Catalytic activity

UDP-N-acetyl-D-glucosamine + (1,4-(N-acetyl-beta-D-glucosaminyl))(n) = UDP + (1,4-(N-acetyl-beta-D-glucosaminyl))(n+1).

Subcellular location

Cell membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the chitin synthase family. Class IV subfamily.

Sequence caution

The sequence AAB71411.1 differs from that shown. Reason: Frameshift at position 1189.

Ontologies

Keywords
   Biological processCell wall biogenesis/degradation
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcell wall organization

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchitin synthase activity

Inferred from electronic annotation. Source: EC

heme binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 12291229Chitin synthase 4
PRO_0000193700

Regions

Transmembrane241 – 26121 Potential
Transmembrane496 – 51621 Potential
Transmembrane1055 – 107521 Potential
Transmembrane1089 – 110921 Potential
Transmembrane1115 – 113521 Potential

Experimental info

Sequence conflict545 – 5462KR → NG in AAB71411. Ref.1

Sequences

Sequence LengthMass (Da)Tools
O13353-1 [UniParc].

Last modified June 12, 2007. Version 2.
Checksum: 388030A667144D55

FASTA1,229137,828
        10         20         30         40         50         60 
MSLPERPGAK ASYEQRNSYR KSPSRRNRPN DIEASGYYPV TGGQHQRGPS VNSFAETIRS 

        70         80         90        100        110        120 
PNSNIESAPL SPSAEQIEHG SDQPFQRKRS LIRPERNRID RDHPNYHYRK HAAKMNTLPS 

       130        140        150        160        170        180 
STGNDPVLED VSGATESGPP SGSNSASGSG VREENIPRKS RKASGRETVA EKSDNTRRRV 

       190        200        210        220        230        240 
STRNSKIVKE GKRKEKIPEQ LRPPSAWNVY CAVITFWSPD FIMKCCGMPA KAQRRAWREK 

       250        260        270        280        290        300 
IGLISLILII MGVVGFLTFG FNQAVCGGPV LRLHINSVDR SYMIFHGTAY NLDGSHHPVA 

       310        320        330        340        350        360 
EGIPKRLDGT GANVVYDLPE GYGGTDGSFM FQNVNGKCKG LITKAPNSDV PSEGDNLAWY 

       370        380        390        400        410        420 
FPCHARNQDG SSQPNMTYPY YFGYACHTTP LARSTFYTQL DKSADVYFTW ADIRNNSRNL 

       430        440        450        460        470        480 
FVYSGNVLDL DLLFWFNRDQ VNIPRRFEEL RDKNNAANRA IRGRDATRTF MASGDRQIAE 

       490        500        510        520        530        540 
CFEDIIKVGT VDTDTVGCIA AKVVLYVSLA LILSVVGARF TLALIFQWFI SKNYAADKTS 

       550        560        570        580        590        600 
QTSDKRKRNK QIEDWSEDIY RAPPRMPGDV GSSVAGASSS DHTSKRSSFL PTTSRFSTVY 

       610        620        630        640        650        660 
GAERSARNKS MPTTMASQAS GGYMGPSSTA YRETNESRTS FLKSDPYATN TAPIEGPGPS 

       670        680        690        700        710        720 
GFIHDSVVPQ PPSDWMPFGF PLAHTICLVT AYSEGELGLR TTLDSVAMTD YPNSHKVILV 

       730        740        750        760        770        780 
ICDGIIKGKG ESKSTPEYVL DMMKDHTIPV EDVEAFSYVA VASGSKRHNM AKIYAGFYDY 

       790        800        810        820        830        840 
GTQSNIPLDK QQRVPMMVVV KCGTPDEMVK SKPGNRGKRD SQIILMSFLQ KVMFDERMTE 

       850        860        870        880        890        900 
LEYEMFNGLW KVTGISPDFY EIVLMVDADT KVFPDSLTHM ISAMVKDPEI MGLCGETKIA 

       910        920        930        940        950        960 
NKRDSWVSAI QVFEYFISHH LAKSFESVFG GVTCLPGCFC MYRIKAPKGA QNYWVPILAN 

       970        980        990       1000       1010       1020 
PDVVEHYSEN VVDTLHKKNL LLLGEDRYLT TLMLRTFPKR KQVFVPQAVC KTTVPDSFMV 

      1030       1040       1050       1060       1070       1080 
LLSQRRRWIN STIHNLMELV LVRDLCGTFC FSMQFVIFIE LIGTLVLPAA IAFTFYVVII 

      1090       1100       1110       1120       1130       1140 
SIINQPPQII PLVLLGLILG LPAILIIITA HSWSYVLWML IYLLSLPVWN FVLPAYAFWK 

      1150       1160       1170       1180       1190       1200 
FDDFSWGDTR KTAGEKTKKA GIEYEGEFDS SKITMKRWAE FERDRRARQS QYWGSRENVT 

      1210       1220 
GGVRTASGVW ASAPPHHHQQ QYDEYYSDA 

« Hide

References

« Hide 'large scale' references
[1]Specht C.A.
Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: Guyane 11.
[2]"The genome sequence of the rice blast fungus Magnaporthe grisea."
Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K., Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D., Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S., Soanes D.M. expand/collapse author list , Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M., Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E., Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.
Nature 434:980-986(2005) [PubMed: 15846337] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 70-15 / FGSC 8958.

Cross-references

Sequence databases

AF020528 Genomic DNA. Translation: AAB71411.1. Frameshift.
CH476830 Genomic DNA. Translation: EDJ97770.1.
RefSeqXP_365117.2.
UniGeneMgr.13504

3D structure databases

ModBaseSearch...

Protein family/group databases

CAZyGT2. Glycosyltransferase Family 2.

Genome annotation databases

GeneID2680870.
KEGGmgr:MGG_09962.

Phylogenomic databases

OMADTKVFPD.

Enzyme and pathway databases

BRENDA2.4.1.16. 5953.

Family and domain databases

InterProIPR004835. Chitin_synth_fng.
IPR001199. Cyt_B5.
[Graphical view]
PfamPF03142. Chitin_synth_2. 1 hit.
PF00173. Cyt-b5. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCHS4_MAGGR
AccessionPrimary (citable) accession number: O13353
Secondary accession number(s): A4R0F5
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: June 12, 2007
Last modified: November 3, 2009
This is version 56 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents