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Protein

Signal transducer and activator of transcription

Gene

rbtStat1-1

Organism
Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivatorUniRule annotation, DNA-bindingUniRule annotation
Biological processTranscription, Transcription regulationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Signal transducer and activator of transcriptionUniRule annotation
Gene namesi
Name:rbtStat1-1Imported
OrganismiOncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)Imported
Taxonomic identifieri8022 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiProtacanthopterygiiSalmoniformesSalmonidaeSalmoninaeOncorhynchus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotation, NucleusUniRule annotation

PTM / Processingi

Keywords - PTMi

PhosphoproteinUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliO13131
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini568 – 664SH2InterPro annotationAdd BLAST97

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili137 – 164Sequence analysisAdd BLAST28
Coiled coili261 – 288Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the transcription factor STAT family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

HOVERGENiHBG055669

Family and domain databases

CDDicd10372 SH2_STAT1, 1 hit
Gene3Di1.10.532.10, 1 hit
1.10.8.1200, 1 hit
2.60.40.630, 1 hit
3.30.505.10, 1 hit
InterProiView protein in InterPro
IPR008967 p53-like_TF_DNA-bd
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR001217 STAT
IPR038295 STAT1_C_sf
IPR035859 STAT1_SH2
IPR022752 STAT1_TAZ2-bd_C
IPR036535 STAT_N_sf
IPR013800 STAT_TF_alpha
IPR015988 STAT_TF_coiled-coil
IPR013801 STAT_TF_DNA-bd
IPR012345 STAT_TF_DNA-bd_N
IPR013799 STAT_TF_prot_interaction
PANTHERiPTHR11801 PTHR11801, 1 hit
PfamiView protein in Pfam
PF00017 SH2, 1 hit
PF12162 STAT1_TAZ2bind, 1 hit
PF01017 STAT_alpha, 1 hit
PF02864 STAT_bind, 1 hit
PF02865 STAT_int, 1 hit
SMARTiView protein in SMART
SM00964 STAT_int, 1 hit
SUPFAMiSSF47655 SSF47655, 1 hit
SSF48092 SSF48092, 1 hit
SSF49417 SSF49417, 1 hit
SSF55550 SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS50001 SH2, 1 hit

Sequencei

Sequence statusi: Complete.

O13131-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQWCQLQLL ESKYLEQVDQ LYDDSFPMDI RQYLSKWIES IDWENVAVQD
60 70 80 90 100
SLATVRFHDL LAQLDDQHSR FALENNFLLQ HNIRKIKRNL QDHFQEDPVH
110 120 130 140 150
MAMIISRNLK EEQKILAAAK SIETNRENTQ TSMVLEKQKL DNKVKDMKNK
160 170 180 190 200
VQEADQNVKS LEYLQDEHDF KENTLKNREH EMNGLTPKQL EHEKLLIAEM
210 220 230 240 250
CLKLKIKRGE VVGQLAEVLN MAEAVQSDLI SEELAEWKKR QQISCIGGPP
260 270 280 290 300
NACLDQLQNW FTAVAESLQQ VRQQLKELQE LEQKYTYDND PIKQQKGFLE
310 320 330 340 350
GRALTLFRNL LEHSLVVERQ PCMPTHPQRP LVLKTQVQFT VKLRFLVKLQ
360 370 380 390 400
EFNYQLKVKA LFDKDVTEKK GFRKFNILGT NTKVLNMEES NGSLAAEFRH
410 420 430 440 450
LQLKEQKVAG NRTNEGPLIV TEELHCICFE SELNQSGLEL KLETISLPIV
460 470 480 490 500
VISNVSQLPS GWASILWYNM LTSEPKNLKF FLSPPAASWG QLSEVLSWQF
510 520 530 540 550
SSVTKRGLNE EQLGMLADKL LGQKAQRNPE GLIPWTKFCK SLNEKSFPFW
560 570 580 590 600
LWIEAILDLI KRHLLSLWND GCILGFVSKE REKALLTGKC PGTFLLRFSE
610 620 630 640 650
SSRDGAITFT WVEHDQYNKP VFHAVEPYTK KELSAVSLPD IIRTYKVMAA
660 670 680 690 700
ENIPENPLRF LYPDIPKDKS FGKYYARASE ASEPMDVEGS SSTGYMKTEL
710 720 730 740 750
ISVSEVHPSR LQDNMMPMSP DVFGELKRSV APVFQCWTGP KEIDAVMTPD

SDCN
Length:754
Mass (Da):86,873
Last modified:July 1, 1997 - v1
Checksum:i9C88AB12B0DC6777
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U60331 mRNA Translation: AAB60924.1
RefSeqiNP_001118179.1, NM_001124707.1
UniGeneiOmy.38957

Genome annotation databases

GeneIDi100136755

Similar proteinsi

Entry informationi

Entry nameiO13131_ONCMY
AccessioniPrimary (citable) accession number: O13131
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: May 23, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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