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O13111

- O13111_CHICK

UniProt

O13111 - O13111_CHICK

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Protein
Submitted name:

AP-2 transcription factor

Gene
N/A
Organism
Gallus gallus (Chicken)
Status
Unreviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: UniProtKB
  2. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity Source: UniProtKB
  3. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Source: UniProtKB
  4. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Source: UniProtKB
  5. transcription coactivator activity Source: UniProtKB

GO - Biological processi

  1. bone morphogenesis Source: UniProtKB
  2. cellular response to iron ion Source: UniProtKB
  3. embryonic cranial skeleton morphogenesis Source: UniProtKB
  4. embryonic forelimb morphogenesis Source: UniProtKB
  5. eyelid development in camera-type eye Source: UniProtKB
  6. inner ear morphogenesis Source: UniProtKB
  7. kidney development Source: UniProtKB
  8. negative regulation of apoptotic process Source: UniProtKB
  9. negative regulation of myoblast proliferation Source: UniProtKB
  10. negative regulation of reactive oxygen species metabolic process Source: UniProtKB
  11. negative regulation of transcription by competitive promoter binding Source: UniProtKB
  12. negative regulation of transcription from RNA polymerase II promoter Source: UniProtKB
  13. oculomotor nerve formation Source: UniProtKB
  14. optic cup structural organization Source: UniProtKB
  15. optic vesicle morphogenesis Source: UniProtKB
  16. palate development Source: UniProtKB
  17. positive regulation of bone mineralization Source: UniProtKB
  18. positive regulation of tooth mineralization Source: UniProtKB
  19. positive regulation of transcription from RNA polymerase II promoter Source: UniProtKB
  20. sensory perception of sound Source: UniProtKB
  21. transcription from RNA polymerase II promoter Source: GOC
  22. trigeminal nerve development Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
AP-2 transcription factorImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiO13111.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000020815.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG300693.
HOGENOMiHOG000231737.
HOVERGENiHBG002455.
InParanoidiO13111.
KOiK09176.
PhylomeDBiO13111.

Family and domain databases

InterProiIPR004979. TF_AP2.
IPR008121. TF_AP2_alpha_N.
IPR013854. TF_AP2_C.
[Graphical view]
PANTHERiPTHR10812. PTHR10812. 1 hit.
PfamiPF03299. TF_AP-2. 1 hit.
[Graphical view]
PRINTSiPR01749. AP2ATNSCPFCT.
PR01748. AP2TNSCPFCT.

Sequencei

Sequence statusi: Complete.

O13111-1 [UniParc]FASTAAdd to Basket

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MLWKLTDNIK YEECEERHDS ASNGTARLPQ LGAVGQSPYS SAPPLSHTPN    50
ADFQPPYFPP PYQPIYPQSQ DPYSHVNDPY SLNSLHTQPQ PQHPAWPGQR 100
QSQEPSLLHA HRGLPHQLGG LDPRRDYRRH DDLLHGPHGL GAGLADLPLH 150
SIPHAIEDVP HVDDPGINIP DQTVIKKGPV SLSKSNNNAV SSIPINKDAL 200
FGGVVNPNEV FCSVPGRLSL LSSTSKYKVT VAEVQRRLSP PECLNASLLG 250
GVLRRAKSKN GGRSLREKLD KIGLNLPAGR RKAANVTLLT SLVEGEAVHL 300
ARDFGYVCET EFPAKAVAEF LNRQHSDPNE QVTRKNMLLA TKQICKEFTD 350
LLAQDRSPLG NSRPNPILEP GIQSCLTHFN LISHGFGSPA VCAAVTALQN 400
YLTEALKAMD KMYLSNNPNS HTDNSTKSSD KEEKHRK 437
Length:437
Mass (Da):47,985
Last modified:November 1, 1998 - v2
Checksum:i38B23FDDDD6B1937
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U72992 mRNA. Translation: AAB65081.1.
RefSeqiNP_990425.1. NM_205094.1.
UniGeneiGga.2351.

Genome annotation databases

GeneIDi395982.
KEGGigga:395982.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U72992 mRNA. Translation: AAB65081.1 .
RefSeqi NP_990425.1. NM_205094.1.
UniGenei Gga.2351.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9031.ENSGALP00000020815.

Proteomic databases

PaxDbi O13111.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 395982.
KEGGi gga:395982.

Organism-specific databases

CTDi 7020.

Phylogenomic databases

eggNOGi NOG300693.
HOGENOMi HOG000231737.
HOVERGENi HBG002455.
InParanoidi O13111.
KOi K09176.
PhylomeDBi O13111.

Miscellaneous databases

NextBioi 20816046.
PROi O13111.

Family and domain databases

InterProi IPR004979. TF_AP2.
IPR008121. TF_AP2_alpha_N.
IPR013854. TF_AP2_C.
[Graphical view ]
PANTHERi PTHR10812. PTHR10812. 1 hit.
Pfami PF03299. TF_AP-2. 1 hit.
[Graphical view ]
PRINTSi PR01749. AP2ATNSCPFCT.
PR01748. AP2TNSCPFCT.
ProtoNeti Search...

Publicationsi

  1. "Chicken transcription factor AP-2: cloning, expression and its role in outgrowth of facial prominences and limb buds."
    Shen H., Ashique A., Narvey M., Zerucha T., Savino E., Williams T., Richman J.M.
    Dev. Biol. 188:248-266(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: White leghornImported.

Entry informationi

Entry nameiO13111_CHICK
AccessioniPrimary (citable) accession number: O13111
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: November 1, 1998
Last modified: July 9, 2014
This is version 56 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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