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O13111

- O13111_CHICK

UniProt

O13111 - O13111_CHICK

Protein
Submitted name:

AP-2 transcription factor

Gene
N/A
Organism
Gallus gallus (Chicken)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 2 (01 Nov 1998)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: UniProtKB
    2. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity Source: UniProtKB
    3. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Source: UniProtKB
    4. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Source: UniProtKB
    5. transcription coactivator activity Source: UniProtKB

    GO - Biological processi

    1. bone morphogenesis Source: UniProtKB
    2. cellular response to iron ion Source: UniProtKB
    3. embryonic cranial skeleton morphogenesis Source: UniProtKB
    4. embryonic forelimb morphogenesis Source: UniProtKB
    5. eyelid development in camera-type eye Source: UniProtKB
    6. inner ear morphogenesis Source: UniProtKB
    7. kidney development Source: UniProtKB
    8. negative regulation of apoptotic process Source: UniProtKB
    9. negative regulation of myoblast proliferation Source: UniProtKB
    10. negative regulation of reactive oxygen species metabolic process Source: UniProtKB
    11. negative regulation of transcription by competitive promoter binding Source: UniProtKB
    12. negative regulation of transcription from RNA polymerase II promoter Source: UniProtKB
    13. oculomotor nerve formation Source: UniProtKB
    14. optic cup structural organization Source: UniProtKB
    15. optic vesicle morphogenesis Source: UniProtKB
    16. palate development Source: UniProtKB
    17. positive regulation of bone mineralization Source: UniProtKB
    18. positive regulation of tooth mineralization Source: UniProtKB
    19. positive regulation of transcription from RNA polymerase II promoter Source: UniProtKB
    20. sensory perception of sound Source: UniProtKB
    21. transcription from RNA polymerase II promoter Source: GOC
    22. trigeminal nerve development Source: UniProtKB

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    AP-2 transcription factorImported
    OrganismiGallus gallus (Chicken)Imported
    Taxonomic identifieri9031 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: UniProtKB

    PTM / Processingi

    Proteomic databases

    PaxDbiO13111.

    Interactioni

    Protein-protein interaction databases

    STRINGi9031.ENSGALP00000020815.

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG300693.
    HOGENOMiHOG000231737.
    HOVERGENiHBG002455.
    InParanoidiO13111.
    KOiK09176.
    PhylomeDBiO13111.

    Family and domain databases

    InterProiIPR004979. TF_AP2.
    IPR008121. TF_AP2_alpha_N.
    IPR013854. TF_AP2_C.
    [Graphical view]
    PANTHERiPTHR10812. PTHR10812. 1 hit.
    PfamiPF03299. TF_AP-2. 1 hit.
    [Graphical view]
    PRINTSiPR01749. AP2ATNSCPFCT.
    PR01748. AP2TNSCPFCT.

    Sequencei

    Sequence statusi: Complete.

    O13111-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLWKLTDNIK YEECEERHDS ASNGTARLPQ LGAVGQSPYS SAPPLSHTPN    50
    ADFQPPYFPP PYQPIYPQSQ DPYSHVNDPY SLNSLHTQPQ PQHPAWPGQR 100
    QSQEPSLLHA HRGLPHQLGG LDPRRDYRRH DDLLHGPHGL GAGLADLPLH 150
    SIPHAIEDVP HVDDPGINIP DQTVIKKGPV SLSKSNNNAV SSIPINKDAL 200
    FGGVVNPNEV FCSVPGRLSL LSSTSKYKVT VAEVQRRLSP PECLNASLLG 250
    GVLRRAKSKN GGRSLREKLD KIGLNLPAGR RKAANVTLLT SLVEGEAVHL 300
    ARDFGYVCET EFPAKAVAEF LNRQHSDPNE QVTRKNMLLA TKQICKEFTD 350
    LLAQDRSPLG NSRPNPILEP GIQSCLTHFN LISHGFGSPA VCAAVTALQN 400
    YLTEALKAMD KMYLSNNPNS HTDNSTKSSD KEEKHRK 437
    Length:437
    Mass (Da):47,985
    Last modified:November 1, 1998 - v2
    Checksum:i38B23FDDDD6B1937
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U72992 mRNA. Translation: AAB65081.1.
    RefSeqiNP_990425.1. NM_205094.1.
    UniGeneiGga.2351.

    Genome annotation databases

    GeneIDi395982.
    KEGGigga:395982.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U72992 mRNA. Translation: AAB65081.1 .
    RefSeqi NP_990425.1. NM_205094.1.
    UniGenei Gga.2351.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9031.ENSGALP00000020815.

    Proteomic databases

    PaxDbi O13111.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 395982.
    KEGGi gga:395982.

    Organism-specific databases

    CTDi 7020.

    Phylogenomic databases

    eggNOGi NOG300693.
    HOGENOMi HOG000231737.
    HOVERGENi HBG002455.
    InParanoidi O13111.
    KOi K09176.
    PhylomeDBi O13111.

    Miscellaneous databases

    NextBioi 20816046.
    PROi O13111.

    Family and domain databases

    InterProi IPR004979. TF_AP2.
    IPR008121. TF_AP2_alpha_N.
    IPR013854. TF_AP2_C.
    [Graphical view ]
    PANTHERi PTHR10812. PTHR10812. 1 hit.
    Pfami PF03299. TF_AP-2. 1 hit.
    [Graphical view ]
    PRINTSi PR01749. AP2ATNSCPFCT.
    PR01748. AP2TNSCPFCT.
    ProtoNeti Search...

    Publicationsi

    1. "Chicken transcription factor AP-2: cloning, expression and its role in outgrowth of facial prominences and limb buds."
      Shen H., Ashique A., Narvey M., Zerucha T., Savino E., Williams T., Richman J.M.
      Dev. Biol. 188:248-266(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: White leghornImported.

    Entry informationi

    Entry nameiO13111_CHICK
    AccessioniPrimary (citable) accession number: O13111
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 1, 1997
    Last sequence update: November 1, 1998
    Last modified: October 1, 2014
    This is version 57 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)