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UniProtKB - O13007 (O13007_ICTPU)

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Protein

POU domain protein

Gene

Oct-2

Organism
Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • enhancer sequence-specific DNA binding Source: AgBase
  • transcription coactivator binding Source: AgBase
  • transcription factor activity, sequence-specific DNA binding Source: AgBase
Complete GO annotation...

GO - Biological processi

  • positive regulation of gene expression Source: AgBase
  • positive regulation of transcription, DNA-templated Source: AgBase
  • transcription, DNA-templated Source: UniProtKB-UniRule
Complete GO annotation...

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:Oct-2Imported
OrganismiIctalurus punctatus (Channel catfish) (Silurus punctatus)Imported
Taxonomic identifieri7998 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Siluriformes › Ictaluridae › Ictalurus

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

  • nucleus Source: AgBase
Complete GO annotation...

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

GO - Molecular functioni

  • transcription coactivator binding Source: AgBase
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliO13007.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini197 – 271POU-specificInterPro annotationAdd BLAST75
Domaini297 – 357Homeobox DNA-bindingInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG052783.
KOiK09364.

Family and domain databases

InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_dom.
IPR000972. TF_octamer.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
PRINTSiPR00029. OCTAMER.
PR00028. POUDOMAIN.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiView protein in PROSITE
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.

Sequencei

Sequence statusi: Complete.

O13007-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKTAPIAAM DYSHLWLPDI RMSKPIEVEN PAADSPMENT GDSERNGSDS 
        60         70         80         90        100
NNQIPSMKIS PFSLSPTLSA SNKAKLEECG EMSPASVQAT PTQTPLSHTQ 
       110        120        130        140        150
LMLTGSQLAG DIQQLLQLQQ LVLVPGHPLS SPAQFLLPQA QQGQQGLLQT 
       160        170        180        190        200
PNLIPLPQQN QGGLLSAPPA LGLQAQQREK VMESSVSTVT PVTSHAEEPS 
       210        220        230        240        250
DLEELEQFAR TFKQRRIKLG FTQGDVGLAM GKLYGNDFSQ TTISRFEALN 
       260        270        280        290        300
LSFKNMCKLK PLLEKWLTDA ETMSMDSTLP SPSSLSSPSL GFEGLPARRR 
       310        320        330        340        350
KKRTSIETNV RVALERSFST NQKPTSEEIL LIAEQLNMEK EVIRVWFCNR 
       360        370        380        390        400
RQKEKRINPS SATPPLPSQP QPASHKPPCY SPHMMQGQGP SQPVTSLSTA 
       410        420        430        440        450
ATTMSSVCPL TPTGPSSSST PSPVTPSPRS DASPVPATHT LNLNTGSWRH 
       460        470        480
KNGDVSNYIT DFAANLSSGS QWWSNHHFQS
Length:480
Mass (Da):52,254
Last modified:July 1, 1997 - v1
Checksum:i3C1AB0A5911A1288
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y12652 mRNA. Translation: CAA73199.1.
RefSeqiNP_001187100.1. NM_001200171.1.
UniGeneiIpu.4476.
Ipu.97180.

Genome annotation databases

GeneIDi100304591.
KEGGiipu:100304591.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiO13007_ICTPU
AccessioniPrimary (citable) accession number: O13007
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: July 5, 2017
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)