Oct-2

Functionⁱ

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
DNA bindingⁱ	299 – 358	HomeoboxPROSITE-ProRule annotationAdd BLAST		60

GO - Molecular functionⁱ

DNA binding transcription factor activity
Source: AgBase
Inferred from direct assayⁱ
- 19041136
enhancer sequence-specific DNA binding
Source: AgBase
Inferred from direct assayⁱ
- 17266766
- 19041136
transcription coactivator binding
Source: AgBase
Inferred from mutant phenotypeⁱ
- 19041136

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

positive regulation of gene expression
Source: AgBase
Inferred from direct assayⁱ
- 17266766
positive regulation of transcription, DNA-templated
Source: AgBase
Inferred from direct assayⁱ
- 19041136
transcription, DNA-templated Source: UniProtKB-UniRule

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological process	Transcription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: POU domain proteinUniRule annotation
Gene namesⁱ	Name:Oct-2Imported Synonyms:oct2Imported, pou2f2Imported
Organismⁱ	Ictalurus punctatus (Channel catfish) (Silurus punctatus)Imported
Taxonomic identifierⁱ	7998 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Osteoglossocephalai › Clupeocephala › Otomorpha › Ostariophysi › Otophysi › Characiphysae › Siluriformes › Siluroidei › Ictaluridae › Ictalurus
Proteomesⁱ	UP000221080 Componentⁱ: Genome assembly

Keywords - Cellular componentⁱ

NucleusPROSITE-ProRule annotationSAAS annotation

Interactionⁱ

GO - Molecular functionⁱ

transcription coactivator binding
Source: AgBase
Inferred from mutant phenotypeⁱ
- 19041136

View the complete GO annotation on QuickGO ...

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	O13007.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	197 – 271	POU-specificInterPro annotationAdd BLAST		75
Domainⁱ	297 – 357	HomeoboxInterPro annotationAdd BLAST		61

Sequence similaritiesⁱ

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation

Keywords - Domainⁱ

HomeoboxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

HOVERGENⁱ	HBG052783.
KEGG Orthology (KO) More...KOⁱ	K09364.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00086. homeodomain. 1 hit.
InterProⁱ	View protein in InterPro IPR009057. Homeobox-like_sf. IPR017970. Homeobox_CS. IPR001356. Homeobox_dom. IPR010982. Lambda_DNA-bd_dom_sf. IPR013847. POU. IPR000327. POU_dom. IPR000972. TF_octamer.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00046. Homeobox. 1 hit. PF00157. Pou. 1 hit.
PRINTSⁱ	PR00029. OCTAMER. PR00028. POUDOMAIN.
SMARTⁱ	View protein in SMART SM00389. HOX. 1 hit. SM00352. POU. 1 hit.
SUPFAMⁱ	SSF46689. SSF46689. 1 hit. SSF47413. SSF47413. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. PS00035. POU_1. 1 hit. PS00465. POU_2. 1 hit. PS51179. POU_3. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

O13007-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MTKTAPIAAM DYSHLWLPDI RMSKPIEVEN PAADSPMENT GDSERNGSDS 
        60         70         80         90        100
NNQIPSMKIS PFSLSPTLSA SNKAKLEECG EMSPASVQAT PTQTPLSHTQ 
       110        120        130        140        150
LMLTGSQLAG DIQQLLQLQQ LVLVPGHPLS SPAQFLLPQA QQGQQGLLQT 
       160        170        180        190        200
PNLIPLPQQN QGGLLSAPPA LGLQAQQREK VMESSVSTVT PVTSHAEEPS 
       210        220        230        240        250
DLEELEQFAR TFKQRRIKLG FTQGDVGLAM GKLYGNDFSQ TTISRFEALN 
       260        270        280        290        300
LSFKNMCKLK PLLEKWLTDA ETMSMDSTLP SPSSLSSPSL GFEGLPARRR 
       310        320        330        340        350
KKRTSIETNV RVALERSFST NQKPTSEEIL LIAEQLNMEK EVIRVWFCNR 
       360        370        380        390        400
RQKEKRINPS SATPPLPSQP QPASHKPPCY SPHMMQGQGP SQPVTSLSTA 
       410        420        430        440        450
ATTMSSVCPL TPTGPSSSST PSPVTPSPRS DASPVPATHT LNLNTGSWRH 
       460        470        480
KNGDVSNYIT DFAANLSSGS QWWSNHHFQS

Length:480

Mass (Da):52,254

Last modified:July 1, 1997 - v1

Checksum:ⁱ3C1AB0A5911A1288

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	Y12652 mRNA. Translation: CAA73199.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001187100.1. NM_001200171.1.
UniGeneⁱ	Ipu.4476. Ipu.97180.

Genome annotation databases

GeneIDⁱ	100304591.
KEGGⁱ	ipu:100304591.

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
O13007	O13006	Ictalurus punctatus (Channel catfish) (Silurus punctatus)	480	UniRef90_O13007	Cluster: POU domain protein	2

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
O13007	Q00196-4 UPI00070447E1 UPI00072F6BFD UPI0009815132 UPI0003F12BF2 UPI0003F084A3 UPI00063CB097 UPI000333E017 UPI0005406B4F UPI00063C0AEA +41	Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus) Ovis aries (Sheep) Castor canadensis (Beaver) Chrysochloris asiatica (Cape golden mole) Elephantulus edwardii (Cape long-eared elephant shrew) Odobenus rosmarus divergens (Pacific walrus) Octodon degus (Degu) (Sciurus degus) Loxodonta africana (African elephant) Trichechus manatus latirostris (Florida manatee) Ochotona princeps (Southern American pika) And more	400	UniRef50_Q00196-4	Cluster: Isoform OCT2.4 of POU domain, class 2, transcription factor 2	52

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	Y12652 mRNA. Translation: CAA73199.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001187100.1. NM_001200171.1.
UniGeneⁱ	Ipu.4476. Ipu.97180.

3D structure databases

ProteinModelPortalⁱ	O13007.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	100304591.
KEGGⁱ	ipu:100304591.

Organism-specific databases

CTDⁱ	5452.

CTDⁱ

5452.

Phylogenomic databases

HOVERGENⁱ	HBG052783.
KEGG Orthology (KO) More...KOⁱ	K09364.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00086. homeodomain. 1 hit.
InterProⁱ	View protein in InterPro IPR009057. Homeobox-like_sf. IPR017970. Homeobox_CS. IPR001356. Homeobox_dom. IPR010982. Lambda_DNA-bd_dom_sf. IPR013847. POU. IPR000327. POU_dom. IPR000972. TF_octamer.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00046. Homeobox. 1 hit. PF00157. Pou. 1 hit.
PRINTSⁱ	PR00029. OCTAMER. PR00028. POUDOMAIN.
SMARTⁱ	View protein in SMART SM00389. HOX. 1 hit. SM00352. POU. 1 hit.
SUPFAMⁱ	SSF46689. SSF46689. 1 hit. SSF47413. SSF47413. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. PS00035. POU_1. 1 hit. PS00465. POU_2. 1 hit. PS51179. POU_3. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	O13007_ICTPU
Accessionⁱ	O13007Primary (citable) accession number: O13007
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	July 1, 1997
	Last sequence update:	July 1, 1997
	Last modified:	March 28, 2018
	This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - O13007 (O13007_ICTPU)

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POU domain protein

Select a section on the left to see content.

Functionⁱ

Regions

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Nucleus

Nucleus

Keywords - Cellular componentⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - O13007 (O13007_ICTPU)

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POU domain protein

Oct-2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ