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Protein

POU domain protein

Gene

Oct-2

Organism
Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • enhancer sequence-specific DNA binding Source: AgBase
  • transcription coactivator binding Source: AgBase
  • transcription factor activity, sequence-specific DNA binding Source: AgBase

GO - Biological processi

  • positive regulation of gene expression Source: AgBase
  • positive regulation of transcription, DNA-templated Source: AgBase
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

TranscriptionUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:Oct-2Imported
OrganismiIctalurus punctatus (Channel catfish) (Silurus punctatus)Imported
Taxonomic identifieri7998 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiSiluriformesIctaluridaeIctalurus

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

  • nucleus Source: AgBase
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Interactioni

GO - Molecular functioni

  • transcription coactivator binding Source: AgBase

Structurei

3D structure databases

ProteinModelPortaliO13007.
SMRiO13007. Positions 198-359.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini197 – 27175POU-specificInterPro annotationAdd
BLAST
Domaini297 – 35761Homeobox DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation
Contains 1 POU-specific domain.UniRule annotation
Contains 1 homeobox DNA-binding domain.UniRule annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG052783.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_dom.
IPR000972. TF_octamer.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00029. OCTAMER.
PR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O13007-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKTAPIAAM DYSHLWLPDI RMSKPIEVEN PAADSPMENT GDSERNGSDS
60 70 80 90 100
NNQIPSMKIS PFSLSPTLSA SNKAKLEECG EMSPASVQAT PTQTPLSHTQ
110 120 130 140 150
LMLTGSQLAG DIQQLLQLQQ LVLVPGHPLS SPAQFLLPQA QQGQQGLLQT
160 170 180 190 200
PNLIPLPQQN QGGLLSAPPA LGLQAQQREK VMESSVSTVT PVTSHAEEPS
210 220 230 240 250
DLEELEQFAR TFKQRRIKLG FTQGDVGLAM GKLYGNDFSQ TTISRFEALN
260 270 280 290 300
LSFKNMCKLK PLLEKWLTDA ETMSMDSTLP SPSSLSSPSL GFEGLPARRR
310 320 330 340 350
KKRTSIETNV RVALERSFST NQKPTSEEIL LIAEQLNMEK EVIRVWFCNR
360 370 380 390 400
RQKEKRINPS SATPPLPSQP QPASHKPPCY SPHMMQGQGP SQPVTSLSTA
410 420 430 440 450
ATTMSSVCPL TPTGPSSSST PSPVTPSPRS DASPVPATHT LNLNTGSWRH
460 470 480
KNGDVSNYIT DFAANLSSGS QWWSNHHFQS
Length:480
Mass (Da):52,254
Last modified:July 1, 1997 - v1
Checksum:i3C1AB0A5911A1288
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y12652 mRNA. Translation: CAA73199.1.
RefSeqiNP_001187100.1. NM_001200171.1.
UniGeneiIpu.4476.

Genome annotation databases

GeneIDi100304591.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y12652 mRNA. Translation: CAA73199.1.
RefSeqiNP_001187100.1. NM_001200171.1.
UniGeneiIpu.4476.

3D structure databases

ProteinModelPortaliO13007.
SMRiO13007. Positions 198-359.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100304591.

Organism-specific databases

CTDi100304591.

Phylogenomic databases

HOVERGENiHBG052783.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_dom.
IPR000972. TF_octamer.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00029. OCTAMER.
PR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO13007_ICTPU
AccessioniPrimary (citable) accession number: O13007
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: May 11, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.