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Protein

Replication enhancer

Gene

C3

Organism
Tomato leaf curl Taiwan virus
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Enhances infectivity and symptom expression.UniRule annotation
Increases viral DNA accumulation.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Host-virus interactionUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Replication enhancerUniRule annotation
Short name:
REnUniRule annotation
Gene namesi
Name:C3Imported
OrganismiTomato leaf curl Taiwan virusImported
Taxonomic identifieri196093 [NCBI]
Taxonomic lineageiVirusesssDNA virusesGeminiviridaeBegomovirus

Interactioni

Subunit structurei

Homooligomer. Interacts with the replication-associated protein (REP). Interacts with host proliferating cell nuclear antigen (PCNA). Interacts with host retinoblastoma-related protein 1 (RBR1), and may thereby deregulate the host cell cycle. Oligomerization and interaction with PCNA are necessary for optimal replication enhancement.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the geminiviridae replication enhancer protein family.UniRule annotation

Family and domain databases

InterProiIPR000657. Gemini_AL3.
[Graphical view]
PfamiPF01407. Gemini_AL3. 1 hit.
[Graphical view]
PRINTSiPR00231. GEMCOATAL3.
ProDomiPD001172. Gemini_AL3. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

O12278-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSRTGELIT AAQAENGVYT WTVNNPLYFK ITQHNQRPFL QNHDVMTIQI
60 70 80 90 100
QFNYNLRKAL GIHQCFLICQ IWTRLQPQTS HFLRVFKYQC MKYLDNLGVI
110 120 130
SLNNVIRAMT NVLYNVIEGT VDAQFSHIIT FKIY
Length:134
Mass (Da):15,747
Last modified:July 1, 1997 - v1
Checksum:iE7EE9633DA119770
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U88692 Genomic DNA. Translation: AAB61143.1.
RefSeqiNP_632016.1. NC_003898.1.

Genome annotation databases

GeneIDi944517.
KEGGivg:944517.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U88692 Genomic DNA. Translation: AAB61143.1.
RefSeqiNP_632016.1. NC_003898.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi944517.
KEGGivg:944517.

Family and domain databases

InterProiIPR000657. Gemini_AL3.
[Graphical view]
PfamiPF01407. Gemini_AL3. 1 hit.
[Graphical view]
PRINTSiPR00231. GEMCOATAL3.
ProDomiPD001172. Gemini_AL3. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Publicationsi

  1. "Molecular characterization of a tomato leaf curl geminivirus associated with tomatoes in Taiwan."
    Chiang B.T., Green S.K., Tsai W.S., Nakhla M.K., Maxwell D.P.
    Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: TaiwanImported.

Entry informationi

Entry nameiO12278_9GEMI
AccessioniPrimary (citable) accession number: O12278
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: June 8, 2016
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.