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Protein

Virion infectivity factor

Gene

vif

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Biological processi

Keywordsi

Biological processHost-virus interactionSAAS annotation, Ubl conjugation pathwaySAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Virion infectivity factorUniRule annotation
Gene namesi
Name:vifImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

  • Host cell membrane SAAS annotation; Peripheral membrane protein SAAS annotation; Cytoplasmic side SAAS annotation
  • Host cytoplasm UniRule annotation
  • Host cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation
  • Virion UniRule annotation
  • Note: In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor.UniRule annotation
  • Virion SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

Host cell membraneSAAS annotation, Host cytoplasmSAAS annotation, Host membrane, Membrane, VirionSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the primate lentivirus group Vif protein family.UniRule annotationSAAS annotation

Family and domain databases

InterProiView protein in InterPro
IPR000475. Viral_infect.
PfamiView protein in Pfam
PF00559. Vif. 1 hit.
PRINTSiPR00349. VIRIONINFFCT.

Sequencei

Sequence statusi: Complete.

O11963-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENRWQVMIV WQVDRMRIRT WKSLVKHHMY TSGKAKKWVY RHHYESTHPR
60 70 80 90 100
ISSEVHIPLG DAKLVITTYW GLHTGERDWH LGQGVSIEWR KRRYSTQVDP
110 120 130 140 150
GLADQLIHLH YFDCFSESAI RKAIVGRLVS PRCEYQAGHN KVGSLQYLAL
160 170 180 190
AALITPKKIK PPLPSVRKLT EDRWNKPQKT KGHRESHTRN GH
Length:192
Mass (Da):22,587
Last modified:July 1, 1997 - v1
Checksum:iE7996D93A74859E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D70875 Genomic DNA. Translation: BAA20316.1.

Similar proteinsi

Entry informationi

Entry nameiO11963_9HIV1
AccessioniPrimary (citable) accession number: O11963
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: November 22, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)