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Protein

Probable endochitinase

Gene

ORF124

Organism
Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei304Proton donorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation

Protein family/group databases

CAZyiGH18. Glycoside Hydrolase Family 18.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable endochitinase (EC:3.2.1.14)
Gene namesi
ORF Names:ORF124
OrganismiOrgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV)
Taxonomic identifieri262177 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageBaculoviridaeAlphabaculovirus
Virus hostiOrgyia pseudotsugata (Douglas-fir tussock moth) [TaxID: 33414]
Proteomesi
  • UP000009248 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Host endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_000001195117 – 550Probable endochitinaseAdd BLAST534

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi146N-linked (GlcNAc...); by hostSequence analysis1
Glycosylationi172N-linked (GlcNAc...); by hostSequence analysis1
Glycosylationi344N-linked (GlcNAc...); by hostSequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliO10363.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi547 – 550Prevents secretion from ERPROSITE-ProRule annotation4

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

KOiK01183.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.10.50.10. 1 hit.
3.20.20.80. 2 hits.
InterProiIPR011583. Chitinase_II.
IPR029070. Chitinase_insertion.
IPR013540. ChitinaseA_N.
IPR001223. Glyco_hydro18_cat.
IPR001579. Glyco_hydro_18_chit_AS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR022409. PKD/Chitinase_dom.
[Graphical view]
PfamiPF08329. ChitinaseA_N. 1 hit.
PF00704. Glyco_hydro_18. 1 hit.
[Graphical view]
SMARTiSM00636. Glyco_18. 1 hit.
SM00089. PKD. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF54556. SSF54556. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEiPS01095. CHITINASE_18. 1 hit.
PS00014. ER_TARGET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O10363-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLHYLATILW LAVAHASPGT PVIDWADRNY ALVSVNSEAT AYENLVERKA
60 70 80 90 100
GVSVPVSWNV WNGGVGDMAY VLFNENQVWK GAAAAKRATI DVSKSGQFNM
110 120 130 140 150
RVKLCDDDGF SVSEPVTVRV ADTDGGHLSP LEYAWGENNK PGRPHNKTVA
160 170 180 190 200
AYFVEWGVYG RGFPVDKVPL PNLSHLLYGF IPICGGDGLN DALKTIPGSF
210 220 230 240 250
EALQRSCKGR ADFKVAIHDP WAAIQKPQKG VSAWNEPYKG NFGQLMAAKL
260 270 280 290 300
ANPHLKILPS IGGWTLSDPF YFMHDADKRR VFVESVKEFL QVWKFFDGVD
310 320 330 340 350
IDWEFPGGKG ANPALGNGER DADTYLVLLK ELRAMLDELQ LQTNKTYELT
360 370 380 390 400
SAISSGYDKI AVVKYDAAQR FLDKIFLMSY DFKGAWSNTD LGYQTTLYAP
410 420 430 440 450
SWNANELYTT DHAVKLLTGQ GVAAHKLIVG VAMYGRGWTG VSGYAGDKYF
460 470 480 490 500
SGTADGPVPG TWENGVVDYR QINNELSKYI YRFDAAAKAA YVFNKERGDL
510 520 530 540 550
ISFDSVDSVL AKNVYVQQNG LGGLFAWEID ADNGDLLNAM NERVRVKDEL
Length:550
Mass (Da):60,734
Last modified:July 1, 1997 - v1
Checksum:i77947F5CF00E07BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75930 Genomic DNA. Translation: AAC59123.1.
RefSeqiNP_046280.1. NC_001875.2.

Genome annotation databases

GeneIDi912030.
KEGGivg:912030.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75930 Genomic DNA. Translation: AAC59123.1.
RefSeqiNP_046280.1. NC_001875.2.

3D structure databases

ProteinModelPortaliO10363.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH18. Glycoside Hydrolase Family 18.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi912030.
KEGGivg:912030.

Phylogenomic databases

KOiK01183.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.10.50.10. 1 hit.
3.20.20.80. 2 hits.
InterProiIPR011583. Chitinase_II.
IPR029070. Chitinase_insertion.
IPR013540. ChitinaseA_N.
IPR001223. Glyco_hydro18_cat.
IPR001579. Glyco_hydro_18_chit_AS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR022409. PKD/Chitinase_dom.
[Graphical view]
PfamiPF08329. ChitinaseA_N. 1 hit.
PF00704. Glyco_hydro_18. 1 hit.
[Graphical view]
SMARTiSM00636. Glyco_18. 1 hit.
SM00089. PKD. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF54556. SSF54556. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEiPS01095. CHITINASE_18. 1 hit.
PS00014. ER_TARGET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCHIT_NPVOP
AccessioniPrimary (citable) accession number: O10363
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 1, 1997
Last modified: November 30, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.