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O10274

- PTP1_NPVOP

UniProt

O10274 - PTP1_NPVOP

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Protein
Putative tyrosine-protein phosphatase 1
Gene
PTP-1, ORF10
Organism
Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Could be inactive as the active site cysteine is modified to tryptophan.

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei162 – 1621Equivalent of active site Cys

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC
  2. protein tyrosine/serine/threonine phosphatase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein phosphatase 1 (EC:3.1.3.48)
Short name:
Protein-tyrosine phosphatase 1
Gene namesi
Name:PTP-1
ORF Names:ORF10
OrganismiOrgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV)
Taxonomic identifieri262177 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageBaculoviridaeAlphabaculovirus
Virus hostiOrgyia pseudotsugata (Douglas-fir tussock moth) [TaxID: 33414]
ProteomesiUP000009248: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 220220Putative tyrosine-protein phosphatase 1
PRO_0000094882Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO10274.
SMRiO10274. Positions 44-210.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR000340. Dual-sp_phosphatase_cat-dom.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
[Graphical view]
PfamiPF00782. DSPc. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS50056. TYR_PHOSPHATASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O10274-1 [UniParc]FASTAAdd to Basket

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MLTSRRWAVI YTRTSERNCG GAWCTNGVRR RRQVHLPSVR ARAMFPDRWH    50
EYTACGAVIE GTRLLCFKVP LNAELFEYVT SDEDRWTAAS VLARHSALGA 100
VIDLTNTARY YDGAQMVKMG LLYKKIRVPG RAVPDDDIVA EFIETVDEFF 150
RRCPTMLVAV HWTHGLNRSG YLVCRYMVER LGVSPTDAIA RFETARGHKI 200
ERTNYLQDLL ARKHVRGQPN 220
Length:220
Mass (Da):25,234
Last modified:July 1, 1997 - v1
Checksum:iD3FC093F1953D425
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U75930 Genomic DNA. Translation: AAC59009.1.
RefSeqiNP_046166.1. NC_001875.2.

Genome annotation databases

GeneIDi912096.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U75930 Genomic DNA. Translation: AAC59009.1 .
RefSeqi NP_046166.1. NC_001875.2.

3D structure databases

ProteinModelPortali O10274.
SMRi O10274. Positions 44-210.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 912096.

Family and domain databases

Gene3Di 3.90.190.10. 1 hit.
InterProi IPR000340. Dual-sp_phosphatase_cat-dom.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
[Graphical view ]
Pfami PF00782. DSPc. 1 hit.
[Graphical view ]
SUPFAMi SSF52799. SSF52799. 1 hit.
PROSITEi PS50056. TYR_PHOSPHATASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The sequence of the Orgyia pseudotsugata multinucleocapsid nuclear polyhedrosis virus genome."
    Ahrens C.H., Russell R.R., Funk C.J., Evans J., Harwood S., Rohrmann G.F.
    Virology 229:381-399(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiPTP1_NPVOP
AccessioniPrimary (citable) accession number: O10274
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 1, 1997
Last modified: June 11, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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