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O10274

- PTP1_NPVOP

UniProt

O10274 - PTP1_NPVOP

Protein

Putative tyrosine-protein phosphatase 1

Gene

PTP-1

Organism
Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (01 Jul 1997)
      Previous versions | rss
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    Functioni

    Could be inactive as the active site cysteine is modified to tryptophan.

    Catalytic activityi

    Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei162 – 1621Equivalent of active site Cys

    GO - Molecular functioni

    1. protein tyrosine/serine/threonine phosphatase activity Source: InterPro
    2. protein tyrosine phosphatase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative tyrosine-protein phosphatase 1 (EC:3.1.3.48)
    Short name:
    Protein-tyrosine phosphatase 1
    Gene namesi
    Name:PTP-1
    ORF Names:ORF10
    OrganismiOrgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV)
    Taxonomic identifieri262177 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageBaculoviridaeAlphabaculovirus
    Virus hostiOrgyia pseudotsugata (Douglas-fir tussock moth) [TaxID: 33414]
    ProteomesiUP000009248: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 220220Putative tyrosine-protein phosphatase 1PRO_0000094882Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliO10274.
    SMRiO10274. Positions 44-210.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    Gene3Di3.90.190.10. 1 hit.
    InterProiIPR000340. Dual-sp_phosphatase_cat-dom.
    IPR029021. Prot-tyrosine_phosphatase-like.
    IPR000387. Tyr/Dual-sp_Pase.
    [Graphical view]
    PfamiPF00782. DSPc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52799. SSF52799. 1 hit.
    PROSITEiPS50056. TYR_PHOSPHATASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O10274-1 [UniParc]FASTAAdd to Basket

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    MLTSRRWAVI YTRTSERNCG GAWCTNGVRR RRQVHLPSVR ARAMFPDRWH    50
    EYTACGAVIE GTRLLCFKVP LNAELFEYVT SDEDRWTAAS VLARHSALGA 100
    VIDLTNTARY YDGAQMVKMG LLYKKIRVPG RAVPDDDIVA EFIETVDEFF 150
    RRCPTMLVAV HWTHGLNRSG YLVCRYMVER LGVSPTDAIA RFETARGHKI 200
    ERTNYLQDLL ARKHVRGQPN 220
    Length:220
    Mass (Da):25,234
    Last modified:July 1, 1997 - v1
    Checksum:iD3FC093F1953D425
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U75930 Genomic DNA. Translation: AAC59009.1.
    RefSeqiNP_046166.1. NC_001875.2.

    Genome annotation databases

    GeneIDi912096.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U75930 Genomic DNA. Translation: AAC59009.1 .
    RefSeqi NP_046166.1. NC_001875.2.

    3D structure databases

    ProteinModelPortali O10274.
    SMRi O10274. Positions 44-210.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 912096.

    Family and domain databases

    Gene3Di 3.90.190.10. 1 hit.
    InterProi IPR000340. Dual-sp_phosphatase_cat-dom.
    IPR029021. Prot-tyrosine_phosphatase-like.
    IPR000387. Tyr/Dual-sp_Pase.
    [Graphical view ]
    Pfami PF00782. DSPc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52799. SSF52799. 1 hit.
    PROSITEi PS50056. TYR_PHOSPHATASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The sequence of the Orgyia pseudotsugata multinucleocapsid nuclear polyhedrosis virus genome."
      Ahrens C.H., Russell R.R., Funk C.J., Evans J., Harwood S., Rohrmann G.F.
      Virology 229:381-399(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiPTP1_NPVOP
    AccessioniPrimary (citable) accession number: O10274
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: July 1, 1997
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3