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Protein

Putative tyrosine-protein phosphatase 1

Gene

PTP-1

Organism
Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Could be inactive as the active site cysteine is modified to tryptophan.

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei162Equivalent of active site Cys1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein phosphatase 1 (EC:3.1.3.48)
Short name:
Protein-tyrosine phosphatase 1
Gene namesi
Name:PTP-1
ORF Names:ORF10
OrganismiOrgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV)
Taxonomic identifieri262177 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageBaculoviridaeAlphabaculovirus
Virus hostiOrgyia pseudotsugata (Douglas-fir tussock moth) [TaxID: 33414]
Proteomesi
  • UP000009248 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000948821 – 220Putative tyrosine-protein phosphatase 1Add BLAST220

Structurei

3D structure databases

ProteinModelPortaliO10274.
SMRiO10274.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

OrthoDBiVOG090000UJ.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiView protein in InterPro
IPR000340. Dual-sp_phosphatase_cat-dom.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. TYR_PHOSPHATASE_dom.
PfamiView protein in Pfam
PF00782. DSPc. 1 hit.
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiView protein in PROSITE
PS50056. TYR_PHOSPHATASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O10274-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTSRRWAVI YTRTSERNCG GAWCTNGVRR RRQVHLPSVR ARAMFPDRWH
60 70 80 90 100
EYTACGAVIE GTRLLCFKVP LNAELFEYVT SDEDRWTAAS VLARHSALGA
110 120 130 140 150
VIDLTNTARY YDGAQMVKMG LLYKKIRVPG RAVPDDDIVA EFIETVDEFF
160 170 180 190 200
RRCPTMLVAV HWTHGLNRSG YLVCRYMVER LGVSPTDAIA RFETARGHKI
210 220
ERTNYLQDLL ARKHVRGQPN
Length:220
Mass (Da):25,234
Last modified:July 1, 1997 - v1
Checksum:iD3FC093F1953D425
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75930 Genomic DNA. Translation: AAC59009.1.
RefSeqiNP_046166.1. NC_001875.2.

Genome annotation databases

GeneIDi912096.
KEGGivg:912096.

Similar proteinsi

Entry informationi

Entry nameiPTP1_NPVOP
AccessioniPrimary (citable) accession number: O10274
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 1, 1997
Last modified: September 27, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families