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O10274 (PTP1_NPVOP) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative tyrosine-protein phosphatase 1

Short name=Protein-tyrosine phosphatase 1
EC=3.1.3.48
Gene names
Name:PTP-1
ORF Names:ORF10
OrganismOrgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) [Complete proteome]
Taxonomic identifier262177 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageBaculoviridaeAlphabaculovirus
Virus hostOrgyia pseudotsugata (Douglas-fir tussock moth) [TaxID: 33414]

Protein attributes

Sequence length220 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Could be inactive as the active site cysteine is modified to tryptophan.

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 220220Putative tyrosine-protein phosphatase 1
PRO_0000094882

Sites

Site1621Equivalent of active site Cys

Sequences

Sequence LengthMass (Da)Tools
O10274 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: D3FC093F1953D425

FASTA22025,234
        10         20         30         40         50         60 
MLTSRRWAVI YTRTSERNCG GAWCTNGVRR RRQVHLPSVR ARAMFPDRWH EYTACGAVIE 

        70         80         90        100        110        120 
GTRLLCFKVP LNAELFEYVT SDEDRWTAAS VLARHSALGA VIDLTNTARY YDGAQMVKMG 

       130        140        150        160        170        180 
LLYKKIRVPG RAVPDDDIVA EFIETVDEFF RRCPTMLVAV HWTHGLNRSG YLVCRYMVER 

       190        200        210        220 
LGVSPTDAIA RFETARGHKI ERTNYLQDLL ARKHVRGQPN 

« Hide

References

[1]"The sequence of the Orgyia pseudotsugata multinucleocapsid nuclear polyhedrosis virus genome."
Ahrens C.H., Russell R.R., Funk C.J., Evans J., Harwood S., Rohrmann G.F.
Virology 229:381-399(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U75930 Genomic DNA. Translation: AAC59009.1.
RefSeqNP_046166.1. NC_001875.2.

3D structure databases

ProteinModelPortalO10274.
SMRO10274. Positions 44-210.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID912096.

Phylogenomic databases

ProtClustDBCLSP2509865.

Family and domain databases

InterProIPR000340. Dual-sp_phosphatase_cat-dom.
IPR000387. Tyr/Dual-sp_Pase.
[Graphical view]
PfamPF00782. DSPc. 1 hit.
[Graphical view]
PROSITEPS50056. TYR_PHOSPHATASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePTP1_NPVOP
AccessionPrimary (citable) accession number: O10274
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 1, 1997
Last modified: April 16, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families