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Protein

Tyrosine-protein phosphatase 2

Gene

PTP-2

Organism
Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei96Phosphocysteine intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Tyrosine-protein phosphatase 2 (EC:3.1.3.48)
Alternative name(s):
Protein-tyrosine phosphatase 2
Gene namesi
Name:PTP-2
ORF Names:ORF9
OrganismiOrgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV)
Taxonomic identifieri262177 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageBaculoviridaeAlphabaculovirus
Virus hostiOrgyia pseudotsugata (Douglas-fir tussock moth) [TaxID: 33414]
Proteomesi
  • UP000009248 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000948831 – 160Tyrosine-protein phosphatase 2Add BLAST160

Structurei

3D structure databases

ProteinModelPortaliO10273.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

OrthoDBiVOG090000UJ.

Family and domain databases

CDDicd00127. DSPc. 1 hit.
Gene3Di3.90.190.10. 1 hit.
InterProiView protein in InterPro
IPR000340. Dual-sp_phosphatase_cat-dom.
IPR024950. DUSP.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR016130. Tyr_Pase_AS.
IPR000387. TYR_PHOSPHATASE_dom.
IPR020422. TYR_PHOSPHATASE_DUAL_dom.
PANTHERiPTHR10159. PTHR10159. 1 hit.
PfamiView protein in Pfam
PF00782. DSPc. 1 hit.
SMARTiView protein in SMART
SM00195. DSPc. 1 hit.
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiView protein in PROSITE
PS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50054. TYR_PHOSPHATASE_DUAL. 1 hit.

Sequencei

Sequence statusi: Complete.

O10273-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYEASQIDEH VFVGGYYGDN EAMLRFIENH AIASVISLID SDVAPIRHAL
60 70 80 90 100
GLPVGDHIHV YCEAAPTCAA LPNAMPALYD YMVRRIGEGK RVLVHCYAGA
110 120 130 140 150
SRSAALAVYY LMRSRQMPYQ DALNAVQSKR RVAINDHFVR FLATRCSYRF
160
VNDELKPQIV
Length:160
Mass (Da):17,980
Last modified:July 1, 1997 - v1
Checksum:i51DDA804A554301B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75930 Genomic DNA. Translation: AAC59008.1.
RefSeqiNP_046165.1. NC_001875.2.

Genome annotation databases

GeneIDi912072.
KEGGivg:912072.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75930 Genomic DNA. Translation: AAC59008.1.
RefSeqiNP_046165.1. NC_001875.2.

3D structure databases

ProteinModelPortaliO10273.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi912072.
KEGGivg:912072.

Phylogenomic databases

OrthoDBiVOG090000UJ.

Family and domain databases

CDDicd00127. DSPc. 1 hit.
Gene3Di3.90.190.10. 1 hit.
InterProiView protein in InterPro
IPR000340. Dual-sp_phosphatase_cat-dom.
IPR024950. DUSP.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR016130. Tyr_Pase_AS.
IPR000387. TYR_PHOSPHATASE_dom.
IPR020422. TYR_PHOSPHATASE_DUAL_dom.
PANTHERiPTHR10159. PTHR10159. 1 hit.
PfamiView protein in Pfam
PF00782. DSPc. 1 hit.
SMARTiView protein in SMART
SM00195. DSPc. 1 hit.
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiView protein in PROSITE
PS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50054. TYR_PHOSPHATASE_DUAL. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPTP2_NPVOP
AccessioniPrimary (citable) accession number: O10273
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 1, 1997
Last modified: February 15, 2017
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.