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O09800 (GN_HHV11) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Envelope glycoprotein N
Alternative name(s):
Protein UL49.5
Protein UL49A
Gene names
Name:gN
ORF Names:UL49.5, UL49A
OrganismHuman herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) [Reference proteome]
Taxonomic identifier10299 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeAlphaherpesvirinaeSimplexvirus
Virus hostHomo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length91 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Envelope glycoprotein necessary for proper maturation of gM. May be involved in virus assembly By similarity.

Subunit structure

Interacts with gM By similarity. The gM-gN heterodimer forms the gCII complex By similarity.

Subcellular location

Virion membrane; Single-pass type I membrane protein By similarity. Host membrane; Single-pass type I membrane protein By similarity. Host Golgi apparatus membrane; Single-pass membrane protein By similarity Ref.3.

Sequence similarities

Belongs to the simplexvirus glycoprotein N family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 9168Envelope glycoprotein N
PRO_0000116098

Regions

Topological domain24 – 5532Virion surface Potential
Transmembrane56 – 7621Helical; Potential
Topological domain77 – 9115Intravirion Potential

Sequences

Sequence LengthMass (Da)Tools
O09800 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: 8CF33C769092BB5F

FASTA919,202
        10         20         30         40         50         60 
MGPPRRVCRA GLLFVLLVAL AAGDAGPRGE PPGEEGGRDG IGGARCETQN TGQMSAPGAL 

        70         80         90 
VPFYVGMASM GVCIIAHVCQ ICQRLLAAGH A 

« Hide

References

« Hide 'large scale' references
[1]"The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1."
McGeoch D.J., Dalrymple M.A., Davison A.J., Dolan A., Frame M.C., McNab D., Perry L.J., Scott J.E., Taylor P.
J. Gen. Virol. 69:1531-1574(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"Herpes simplex virus type 1 bacterial artificial chromosome."
Cunningham C., Davison A.J.
Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 17 syn+.
[3]"Comprehensive characterization of extracellular herpes simplex virus type 1 virions."
Loret S., Guay G., Lippe R.
J. Virol. 82:8605-8618(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION.
Strain: F.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X14112 Genomic DNA. Translation: CAA32300.1.
FJ593289 Genomic DNA. Translation: ACM62273.1.
RefSeqNP_044652.1. NC_001806.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Chemistry

ChEMBLCHEMBL2364696.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2703419.

Phylogenomic databases

ProtClustDBCLSP2510168.

Family and domain databases

InterProIPR017376. Herpes_UL49A.
[Graphical view]
PIRSFPIRSF038075. Herpes_UL49A_env. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGN_HHV11
AccessionPrimary (citable) accession number: O09800
Secondary accession number(s): B9VQH8
Entry history
Integrated into UniProtKB/Swiss-Prot: February 2, 2004
Last sequence update: July 1, 1997
Last modified: February 19, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families