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Protein
Submitted name:

SPI6

Gene

Serpinb9

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • acute inflammatory response to antigenic stimulus Source: MGI
  • defense response to bacterium Source: MGI
  • immune response Source: MGI
  • negative regulation by symbiont of host apoptotic process Source: MGI
  • negative regulation of apoptotic process Source: MGI
  • negative regulation of endopeptidase activity Source: MGI
  • negative regulation of T cell apoptotic process Source: MGI
  • positive regulation of gene expression Source: MGI
  • protection from natural killer cell mediated cytotoxicity Source: MGI
  • response to bacterium Source: MGI
  • T cell mediated cytotoxicity Source: MGI

Protein family/group databases

MEROPSiI04.044.

Names & Taxonomyi

Protein namesi
Submitted name:
SPI6Imported
Submitted name:
Serine (Or cysteine) peptidase inhibitor, clade B, member 9Imported
Gene namesi
Name:Serpinb9Imported
ORF Names:mCG_17886Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:106603. Serpinb9.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000045827.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

MINTiMINT-4104570.
STRINGi10090.ENSMUSP00000006391.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 374SERPINInterPro annotationAdd BLAST362

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2392. Eukaryota.
COG4826. LUCA.
GeneTreeiENSGT00760000118789.
HOGENOMiHOG000238519.
HOVERGENiHBG005957.
KOiK13963.
OMAiKILCQDN.
OrthoDBiEOG091G0ION.
TreeFamiTF352619.

Family and domain databases

InterProiView protein in InterPro
IPR000240. Serpin_B9/Maspin.
IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
IPR036186. Serpin_sf.
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiView protein in Pfam
PF00079. Serpin. 1 hit.
PRINTSiPR00676. MASPIN.
SMARTiView protein in SMART
SM00093. SERPIN. 1 hit.
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiView protein in PROSITE
PS00284. SERPIN. 1 hit.

Sequencei

Sequence statusi: Complete.

O08797-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTLSEGNGT FAIHLLKMLC QSNPSKNVCY SPASISSALA MVLLGAKGQT
60 70 80 90 100
AVQISQALGL NKEEGIHQGF QLLLRKLNKP DRKYSLRVAN RLFADKTCEV
110 120 130 140 150
LQTFKESSLH FYDSEMEQLS FAEEAEVSRQ HINTWVSKQT EGKIPELLSG
160 170 180 190 200
GSVDSETRLV LINALYFKGK WHQPFNKEYT MDMPFKINKD EKRPVQMMCR
210 220 230 240 250
EDTYNLAYVK EVQAQVLVMP YEGMELSLVV LLPDEGVDLS KVENNLTFEK
260 270 280 290 300
LTAWMEADFM KSTDVEVFLP KFKLQEDYDM ESLFQRLGVV DVFQEDKADL
310 320 330 340 350
SGMSPERNLC VSKFVHQSVV EINEEGTEAA AASAIIEFCC ASSVPTFCAD
360 370
HPFLFFIRHN KANSILFCGR FSSP
Length:374
Mass (Da):42,259
Last modified:July 1, 1997 - v1
Checksum:i76D9ED10D7875281
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL589871 Genomic DNA. No translation available.
U96700 mRNA. Translation: AAB57812.1.
BC029900 mRNA. Translation: AAH29900.1.
AK035624 mRNA. Translation: BAC29128.1.
AK161581 mRNA. Translation: BAE36475.1.
CH466561 Genomic DNA. Translation: EDL32351.1.
RefSeqiNP_033282.1. NM_009256.3.
XP_006516688.1. XM_006516625.3.
XP_006516689.1. XM_006516626.3.
XP_006516691.1. XM_006516628.3.
XP_006516692.1. XM_006516629.3.
XP_017170957.1. XM_017315468.1.
UniGeneiMm.245041.
Mm.272569.

Genome annotation databases

EnsembliENSMUST00000006391; ENSMUSP00000006391; ENSMUSG00000045827.
ENSMUST00000063191; ENSMUSP00000099002; ENSMUSG00000045827.
GeneIDi20723.
KEGGimmu:20723.
UCSCiuc007pzz.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiO08797_MOUSE
AccessioniPrimary (citable) accession number: O08797
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: November 22, 2017
This is version 144 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported