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Protein
Submitted name:

Protein Serpinb9

Gene

Serpinb9

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • acute inflammatory response to antigenic stimulus Source: MGI
  • defense response to bacterium Source: MGI
  • immune response Source: MGI
  • negative regulation by symbiont of host apoptotic process Source: MGI
  • negative regulation of apoptotic process Source: MGI
  • negative regulation of endopeptidase activity Source: MGI
  • negative regulation of T cell apoptotic process Source: MGI
  • positive regulation of gene expression Source: MGI
  • protection from natural killer cell mediated cytotoxicity Source: MGI
  • response to bacterium Source: MGI
  • T cell mediated cytotoxicity Source: MGI
Complete GO annotation...

Protein family/group databases

MEROPSiI04.044.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Serpinb9Imported
Submitted name:
SPI6Imported
Submitted name:
Serine (Or cysteine) peptidase inhibitor, clade B, member 9Imported
Gene namesi
Name:Serpinb9Imported
ORF Names:mCG_17886Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:106603. Serpinb9.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: MGI
  • cytosol Source: MGI
  • extracellular exosome Source: MGI
  • extracellular space Source: MGI
  • intracellular Source: MGI
  • membrane Source: MGI
  • nucleus Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSMUSG00000045827.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

MINTiMINT-4104570.
STRINGi10090.ENSMUSP00000006391.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 374SERPINInterPro annotationAdd BLAST362

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2392. Eukaryota.
COG4826. LUCA.
GeneTreeiENSGT00760000118789.
HOGENOMiHOG000238519.
HOVERGENiHBG005957.
KOiK13963.
OMAiQPFNKEY.
OrthoDBiEOG091G0ION.
TreeFamiTF352619.

Family and domain databases

InterProiIPR000240. Serpin_B9/Maspin.
IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiPF00079. Serpin. 1 hit.
[Graphical view]
PRINTSiPR00676. MASPIN.
SMARTiSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiPS00284. SERPIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O08797-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTLSEGNGT FAIHLLKMLC QSNPSKNVCY SPASISSALA MVLLGAKGQT
60 70 80 90 100
AVQISQALGL NKEEGIHQGF QLLLRKLNKP DRKYSLRVAN RLFADKTCEV
110 120 130 140 150
LQTFKESSLH FYDSEMEQLS FAEEAEVSRQ HINTWVSKQT EGKIPELLSG
160 170 180 190 200
GSVDSETRLV LINALYFKGK WHQPFNKEYT MDMPFKINKD EKRPVQMMCR
210 220 230 240 250
EDTYNLAYVK EVQAQVLVMP YEGMELSLVV LLPDEGVDLS KVENNLTFEK
260 270 280 290 300
LTAWMEADFM KSTDVEVFLP KFKLQEDYDM ESLFQRLGVV DVFQEDKADL
310 320 330 340 350
SGMSPERNLC VSKFVHQSVV EINEEGTEAA AASAIIEFCC ASSVPTFCAD
360 370
HPFLFFIRHN KANSILFCGR FSSP
Length:374
Mass (Da):42,259
Last modified:July 1, 1997 - v1
Checksum:i76D9ED10D7875281
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL589871 Genomic DNA. No translation available.
U96700 mRNA. Translation: AAB57812.1.
BC029900 mRNA. Translation: AAH29900.1.
AK035624 mRNA. Translation: BAC29128.1.
AK161581 mRNA. Translation: BAE36475.1.
CH466561 Genomic DNA. Translation: EDL32351.1.
RefSeqiNP_033282.1. NM_009256.3.
XP_006516688.1. XM_006516625.3.
XP_006516689.1. XM_006516626.3.
XP_006516691.1. XM_006516628.3.
XP_006516692.1. XM_006516629.3.
XP_017170957.1. XM_017315468.1.
UniGeneiMm.245041.
Mm.272569.

Genome annotation databases

EnsembliENSMUST00000006391; ENSMUSP00000006391; ENSMUSG00000045827.
ENSMUST00000063191; ENSMUSP00000099002; ENSMUSG00000045827.
GeneIDi20723.
KEGGimmu:20723.
UCSCiuc007pzz.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL589871 Genomic DNA. No translation available.
U96700 mRNA. Translation: AAB57812.1.
BC029900 mRNA. Translation: AAH29900.1.
AK035624 mRNA. Translation: BAC29128.1.
AK161581 mRNA. Translation: BAE36475.1.
CH466561 Genomic DNA. Translation: EDL32351.1.
RefSeqiNP_033282.1. NM_009256.3.
XP_006516688.1. XM_006516625.3.
XP_006516689.1. XM_006516626.3.
XP_006516691.1. XM_006516628.3.
XP_006516692.1. XM_006516629.3.
XP_017170957.1. XM_017315468.1.
UniGeneiMm.245041.
Mm.272569.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-4104570.
STRINGi10090.ENSMUSP00000006391.

Protein family/group databases

MEROPSiI04.044.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000006391; ENSMUSP00000006391; ENSMUSG00000045827.
ENSMUST00000063191; ENSMUSP00000099002; ENSMUSG00000045827.
GeneIDi20723.
KEGGimmu:20723.
UCSCiuc007pzz.1. mouse.

Organism-specific databases

CTDi5272.
MGIiMGI:106603. Serpinb9.

Phylogenomic databases

eggNOGiKOG2392. Eukaryota.
COG4826. LUCA.
GeneTreeiENSGT00760000118789.
HOGENOMiHOG000238519.
HOVERGENiHBG005957.
KOiK13963.
OMAiQPFNKEY.
OrthoDBiEOG091G0ION.
TreeFamiTF352619.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000045827.

Family and domain databases

InterProiIPR000240. Serpin_B9/Maspin.
IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiPF00079. Serpin. 1 hit.
[Graphical view]
PRINTSiPR00676. MASPIN.
SMARTiSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiPS00284. SERPIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO08797_MOUSE
AccessioniPrimary (citable) accession number: O08797
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: October 5, 2016
This is version 134 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.