Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O08797

- O08797_MOUSE

UniProt

O08797 - O08797_MOUSE

Protein
Submitted name:

Protein Serpinb9

Gene

Serpinb9

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 113 (01 Oct 2014)
      Sequence version 1 (01 Jul 1997)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. protein binding Source: MGI
    2. serine-type endopeptidase inhibitor activity Source: MGI

    GO - Biological processi

    1. acute inflammatory response to antigenic stimulus Source: MGI
    2. defense response to bacterium Source: MGI
    3. negative regulation of apoptotic process Source: MGI
    4. negative regulation of endopeptidase activity Source: GOC
    5. negative regulation of T cell apoptotic process Source: MGI
    6. regulation of proteolysis Source: RefGenome
    7. T cell mediated cytotoxicity Source: MGI

    Protein family/group databases

    MEROPSiI04.014.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein Serpinb9Imported
    Submitted name:
    SPI6Imported
    Submitted name:
    Serine (Or cysteine) peptidase inhibitor, clade B, member 9Imported
    Gene namesi
    Name:Serpinb9Imported
    ORF Names:mCG_17886Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 13

    Organism-specific databases

    MGIiMGI:106603. Serpinb9.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: MGI
    2. extracellular space Source: InterPro

    Expressioni

    Gene expression databases

    GenevestigatoriO08797.

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-4104570.
    STRINGi10090.ENSMUSP00000099002.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the serpin family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG4826.
    GeneTreeiENSGT00740000114938.
    HOGENOMiHOG000238519.
    HOVERGENiHBG005957.
    InParanoidiO08797.
    KOiK13963.
    OMAiFKLAYIE.
    OrthoDBiEOG7327PB.
    TreeFamiTF352619.

    Family and domain databases

    InterProiIPR000240. Serpin_B9/Maspin.
    IPR023795. Serpin_CS.
    IPR023796. Serpin_dom.
    IPR000215. Serpin_fam.
    [Graphical view]
    PANTHERiPTHR11461. PTHR11461. 1 hit.
    PfamiPF00079. Serpin. 1 hit.
    [Graphical view]
    PRINTSiPR00676. MASPIN.
    SMARTiSM00093. SERPIN. 1 hit.
    [Graphical view]
    SUPFAMiSSF56574. SSF56574. 1 hit.
    PROSITEiPS00284. SERPIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O08797-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNTLSEGNGT FAIHLLKMLC QSNPSKNVCY SPASISSALA MVLLGAKGQT    50
    AVQISQALGL NKEEGIHQGF QLLLRKLNKP DRKYSLRVAN RLFADKTCEV 100
    LQTFKESSLH FYDSEMEQLS FAEEAEVSRQ HINTWVSKQT EGKIPELLSG 150
    GSVDSETRLV LINALYFKGK WHQPFNKEYT MDMPFKINKD EKRPVQMMCR 200
    EDTYNLAYVK EVQAQVLVMP YEGMELSLVV LLPDEGVDLS KVENNLTFEK 250
    LTAWMEADFM KSTDVEVFLP KFKLQEDYDM ESLFQRLGVV DVFQEDKADL 300
    SGMSPERNLC VSKFVHQSVV EINEEGTEAA AASAIIEFCC ASSVPTFCAD 350
    HPFLFFIRHN KANSILFCGR FSSP 374
    Length:374
    Mass (Da):42,259
    Last modified:July 1, 1997 - v1
    Checksum:i76D9ED10D7875281
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL589871 Genomic DNA. No translation available.
    U96700 mRNA. Translation: AAB57812.1.
    BC029900 mRNA. Translation: AAH29900.1.
    AK035624 mRNA. Translation: BAC29128.1.
    AK161581 mRNA. Translation: BAE36475.1.
    CH466561 Genomic DNA. Translation: EDL32351.1.
    RefSeqiNP_033282.1. NM_009256.3.
    XP_006516688.1. XM_006516625.1.
    XP_006516689.1. XM_006516626.1.
    XP_006516690.1. XM_006516627.1.
    XP_006516691.1. XM_006516628.1.
    XP_006516692.1. XM_006516629.1.
    UniGeneiMm.272569.

    Genome annotation databases

    EnsembliENSMUST00000006391; ENSMUSP00000006391; ENSMUSG00000045827.
    ENSMUST00000063191; ENSMUSP00000099002; ENSMUSG00000045827.
    GeneIDi20723.
    KEGGimmu:20723.
    UCSCiuc007pzz.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL589871 Genomic DNA. No translation available.
    U96700 mRNA. Translation: AAB57812.1 .
    BC029900 mRNA. Translation: AAH29900.1 .
    AK035624 mRNA. Translation: BAC29128.1 .
    AK161581 mRNA. Translation: BAE36475.1 .
    CH466561 Genomic DNA. Translation: EDL32351.1 .
    RefSeqi NP_033282.1. NM_009256.3.
    XP_006516688.1. XM_006516625.1.
    XP_006516689.1. XM_006516626.1.
    XP_006516690.1. XM_006516627.1.
    XP_006516691.1. XM_006516628.1.
    XP_006516692.1. XM_006516629.1.
    UniGenei Mm.272569.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-4104570.
    STRINGi 10090.ENSMUSP00000099002.

    Protein family/group databases

    MEROPSi I04.014.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000006391 ; ENSMUSP00000006391 ; ENSMUSG00000045827 .
    ENSMUST00000063191 ; ENSMUSP00000099002 ; ENSMUSG00000045827 .
    GeneIDi 20723.
    KEGGi mmu:20723.
    UCSCi uc007pzz.1. mouse.

    Organism-specific databases

    CTDi 5272.
    MGIi MGI:106603. Serpinb9.

    Phylogenomic databases

    eggNOGi COG4826.
    GeneTreei ENSGT00740000114938.
    HOGENOMi HOG000238519.
    HOVERGENi HBG005957.
    InParanoidi O08797.
    KOi K13963.
    OMAi FKLAYIE.
    OrthoDBi EOG7327PB.
    TreeFami TF352619.

    Miscellaneous databases

    NextBioi 299321.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori O08797.

    Family and domain databases

    InterProi IPR000240. Serpin_B9/Maspin.
    IPR023795. Serpin_CS.
    IPR023796. Serpin_dom.
    IPR000215. Serpin_fam.
    [Graphical view ]
    PANTHERi PTHR11461. PTHR11461. 1 hit.
    Pfami PF00079. Serpin. 1 hit.
    [Graphical view ]
    PRINTSi PR00676. MASPIN.
    SMARTi SM00093. SERPIN. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56574. SSF56574. 1 hit.
    PROSITEi PS00284. SERPIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A new family of 10 murine ovalbumin serpins includes two homologs of proteinase inhibitor 8 and two homologs of the granzyme B inhibitor (proteinase inhibitor 9)."
      Sun J., Ooms L., Bird C.H., Sutton V.R., Trapani J.A., Bird P.I.
      J. Biol. Chem. 272:15434-15441(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Pituitary glandImported and Urinary bladderImported.
    3. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Pituitary glandImported and Urinary bladderImported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Pituitary glandImported and Urinary bladderImported.
    5. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Pituitary glandImported and Urinary bladderImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Urinary bladderImported.
    7. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Pituitary glandImported and Urinary bladderImported.
    8. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    9. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/NImported.
      Tissue: Salivary glandImported.
    10. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Pituitary glandImported.
    11. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Pituitary glandImported and Urinary bladderImported.
    12. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Pituitary glandImported and Urinary bladderImported.
    13. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    14. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    15. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiO08797_MOUSE
    AccessioniPrimary (citable) accession number: O08797
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 1, 1997
    Last sequence update: July 1, 1997
    Last modified: October 1, 2014
    This is version 113 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3