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Protein
Submitted name:

CD44 protein

Gene

Cd44

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
CD44 proteinImported
Gene namesi
Name:Cd44Imported
Synonyms:CD44Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2307. Cd44.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei688 – 709HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500415708922 – 780Sequence analysisAdd BLAST759

Proteomic databases

PaxDbiO08779.

Expressioni

Gene expression databases

GenevisibleiO08779. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000009000.

Structurei

3D structure databases

ProteinModelPortaliO08779.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 124LinkInterPro annotationAdd BLAST90

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IZCP. Eukaryota.
ENOG4111S6T. LUCA.
HOGENOMiHOG000231746.
HOVERGENiHBG003850.
KOiK06256.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR016186. C-type_lectin-like/link.
IPR001231. CD44_antigen.
IPR016187. CTDL_fold.
IPR000538. Link_dom.
[Graphical view]
PfamiPF00193. Xlink. 1 hit.
[Graphical view]
PRINTSiPR00658. CD44.
PR01265. LINKMODULE.
SMARTiSM00445. LINK. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiPS01241. LINK_1. 1 hit.
PS50963. LINK_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O08779-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKVWWHTAW GLLCLLQLSL AQQQIDLNIT CRYAGVFHVE KNGRYSISRT
60 70 80 90 100
EAADLCEAFN TTLPTMAQME LALRKGFETC RYGFIEGHVV IPRIHPNAIC
110 120 130 140 150
AANNTGVYIL LASNTSHYDT YCFNASAPLE EDCTSVTDLP NSFDGPVTIT
160 170 180 190 200
IVNRDGTRYS KKGEYRTHQE DIDASNIIDE DVSSGSTIEK STPEGYILHT
210 220 230 240 250
DLPTSQPTGD RDDAFFIGST LATIASTVYS KSHATAQKQN NWIWSWFGNS
260 270 280 290 300
QSTTQTQDSP TTTATTALMT TPETPPKRQE AQNWFSWFFQ PSESKSHLHT
310 320 330 340 350
TTKMPGTESN TNPTGWKPNE ENEDETDKYP NFSGSGIDDD EDFISSTIAT
360 370 380 390 400
TPWVSAHTKQ NQERTQWNPI HSNPEVLLQT TTRMTDIDRN STSAHGENWT
410 420 430 440 450
QEPQPPFNNH EYQDEEETPH ATSTTWADPN STTEEAATQK EKWFENEWQG
460 470 480 490 500
KNPPTPSEDS HVTEGTTASA HNNHPSQRMT TQSQEDVSWT DFFDPISHPM
510 520 530 540 550
GQGHQTESKD TGSSHSTTLQ PTAAPNTHLV EDLNRTGPLS VTTPQSHSQN
560 570 580 590 600
FSTLPGELEE GEDHPTTSVL PSSTKSGRRR GGSLPRDTTT SLEGYTPQYP
610 620 630 640 650
DTMENGTLFP VTPAKTEVFG ETEGTVATDS NFNVDGSLPG DGDSSMDPRG
660 670 680 690 700
GFDTVTHGSE LAGHSSGNQD SGVTTTSGPA RRPQIPEWLI ILASLLALAL
710 720 730 740 750
ILAVCIAVNS RRRCGQKKKL VINSGNGTVE DRKPSELNGE ASKSQEMVHL
760 770 780
VNKEPTETPD QFMTADETRN LQSVDMKIGV
Length:780
Mass (Da):85,918
Last modified:July 1, 1997 - v1
Checksum:iCC4D35AB1EA7377C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U96138 mRNA. Translation: AAB54002.1.
RefSeqiNP_037056.2. NM_012924.2.
UniGeneiRn.1120.

Genome annotation databases

GeneIDi25406.
KEGGirno:25406.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U96138 mRNA. Translation: AAB54002.1.
RefSeqiNP_037056.2. NM_012924.2.
UniGeneiRn.1120.

3D structure databases

ProteinModelPortaliO08779.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000009000.

Proteomic databases

PaxDbiO08779.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi25406.
KEGGirno:25406.

Organism-specific databases

CTDi960.
RGDi2307. Cd44.

Phylogenomic databases

eggNOGiENOG410IZCP. Eukaryota.
ENOG4111S6T. LUCA.
HOGENOMiHOG000231746.
HOVERGENiHBG003850.
KOiK06256.

Gene expression databases

GenevisibleiO08779. RN.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR016186. C-type_lectin-like/link.
IPR001231. CD44_antigen.
IPR016187. CTDL_fold.
IPR000538. Link_dom.
[Graphical view]
PfamiPF00193. Xlink. 1 hit.
[Graphical view]
PRINTSiPR00658. CD44.
PR01265. LINKMODULE.
SMARTiSM00445. LINK. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiPS01241. LINK_1. 1 hit.
PS50963. LINK_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO08779_RAT
AccessioniPrimary (citable) accession number: O08779
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: November 30, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.