Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Forkhead box E1 (Thyroid transcription factor 2)

Gene

Foxe1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • DNA binding Source: MGI
  • RNA polymerase II transcription factor activity, sequence-specific DNA binding Source: MGI
  • sequence-specific DNA binding Source: Ensembl
  • transcription factor activity, sequence-specific DNA binding Source: RGD

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

DNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Forkhead box E1 (Thyroid transcription factor 2)Imported
Submitted name:
Protein Foxe1Imported
Submitted name:
TTF-2 proteinImported
Gene namesi
Name:Foxe1Imported
Synonyms:ttf-2Imported
ORF Names:rCG_55109Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi621723. Foxe1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000012637.

Structurei

3D structure databases

ProteinModelPortaliO08771.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini54 – 148Fork-head DNA-bindingInterPro annotationAdd BLAST95

Phylogenomic databases

eggNOGiKOG2294. Eukaryota.
COG5025. LUCA.
GeneTreeiENSGT00760000118904.
HOGENOMiHOG000231286.
HOVERGENiHBG051642.
KOiK09398.
OMAiMTAESGP.
OrthoDBiEOG091G0HW9.
PhylomeDBiO08771.
TreeFamiTF316127.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. Fork_head_dom.
IPR018122. TF_fork_head_CS_1.
IPR030456. TF_fork_head_CS_2.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00250. Forkhead. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS00657. FORK_HEAD_1. 1 hit.
PS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O08771-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAESAPPPP PQPEALAAVK EERGEAAAGA GVPAEVAGRG AGGRRRKRPL
60 70 80 90 100
QRGKPPYSYI ALIAMAIAHA PERRLTLGGI YKFITERFPF YRDNPKKWQN
110 120 130 140 150
SIRHNLTLND CFLKIPREAG RPGKGNYWAL DPNAEDMFES GSFLRRRKRF
160 170 180 190 200
KRSDLSTYPA YMHDAAAAAA AAAAAIFPGA VPAARPAYPG AVYAGYAPPL
210 220 230 240 250
AAPPPVYYPA ASPGPCRVFG LVPERPLSPD LGPAPSAAGG SCAFAAAAGA
260 270 280 290 300
PGTGSFQPAV CTGARPVNPA AYAAAYAGPD GAYPQGASSA LFAAAAGRLA
310 320 330 340 350
GPTSPTAGGG SGGVEATVDF YGRTSPGQFG AALGPCYNPS GQLGAGGGGA
360 370
YHSRHATAYP GAVDRFVSAM
Length:370
Mass (Da):37,785
Last modified:July 1, 1997 - v1
Checksum:iEE92C88CEE960F1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07048091 Genomic DNA. No translation available.
Y11321 mRNA. Translation: CAA72174.1.
CH473962 Genomic DNA. Translation: EDL98835.1.
RefSeqiNP_620264.1. NM_138909.1.
UniGeneiRn.26546.

Genome annotation databases

EnsembliENSRNOT00000012637; ENSRNOP00000012637; ENSRNOG00000023497.
GeneIDi192274.
KEGGirno:192274.
UCSCiRGD:621723. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07048091 Genomic DNA. No translation available.
Y11321 mRNA. Translation: CAA72174.1.
CH473962 Genomic DNA. Translation: EDL98835.1.
RefSeqiNP_620264.1. NM_138909.1.
UniGeneiRn.26546.

3D structure databases

ProteinModelPortaliO08771.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000012637.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000012637; ENSRNOP00000012637; ENSRNOG00000023497.
GeneIDi192274.
KEGGirno:192274.
UCSCiRGD:621723. rat.

Organism-specific databases

CTDi2304.
RGDi621723. Foxe1.

Phylogenomic databases

eggNOGiKOG2294. Eukaryota.
COG5025. LUCA.
GeneTreeiENSGT00760000118904.
HOGENOMiHOG000231286.
HOVERGENiHBG051642.
KOiK09398.
OMAiMTAESGP.
OrthoDBiEOG091G0HW9.
PhylomeDBiO08771.
TreeFamiTF316127.

Miscellaneous databases

PROiO08771.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. Fork_head_dom.
IPR018122. TF_fork_head_CS_1.
IPR030456. TF_fork_head_CS_2.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00250. Forkhead. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS00657. FORK_HEAD_1. 1 hit.
PS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO08771_RAT
AccessioniPrimary (citable) accession number: O08771
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: November 30, 2016
This is version 132 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.