ID OXLA_MUSSP Reviewed; 46 AA. AC O08615; DT 30-AUG-2002, integrated into UniProtKB/Swiss-Prot. DT 01-JUL-1997, sequence version 1. DT 16-JUN-2009, entry version 43. DE RecName: Full=L-amino-acid oxidase; DE Short=LAAO; DE Short=LAO; DE EC=1.4.3.2; DE AltName: Full=Interleukin-4-induced protein 1; DE Short=IL4-induced protein 1; DE AltName: Full=Protein Fig-1; DE Flags: Fragment; GN Name=Il4i1; Synonyms=Fig1; OS Mus spretus (Western wild mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus. OX NCBI_TaxID=10096; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND INDUCTION. RX MEDLINE=97225983; PubMed=9122225; DOI=10.1073/pnas.94.6.2507; RA Chu C.C., Paul W.E.; RT "Fig1, an interleukin 4-induced mouse B cell gene isolated by cDNA RT representational difference analysis."; RL Proc. Natl. Acad. Sci. U.S.A. 94:2507-2512(1997). CC -!- FUNCTION: Lysosomal L-amino-acid oxidase with highest specific CC activity with phenylalanine. May play a role in lysosomal antigen CC processing and presentation (By similarity). CC -!- CATALYTIC ACTIVITY: An L-amino acid + H(2)O + O(2) = a 2-oxo acid CC + NH(3) + H(2)O(2). CC -!- COFACTOR: FAD (By similarity). CC -!- SUBCELLULAR LOCATION: Lysosome (By similarity). CC -!- INDUCTION: By interleukin-4. CC -!- SIMILARITY: Belongs to the flavin monoamine oxidase family. FIG1 CC subfamily. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; U80211; AAB51360.1; -; Genomic_DNA. DR MGI; MGI:109552; Il4i1. DR HOVERGEN; O08615; -. DR BRENDA; 1.4.3.2; 291401. DR GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. DR GO; GO:0001716; F:L-amino-acid oxidase activity; IEA:EC. DR GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW. PE 2: Evidence at transcript level; KW FAD; Flavoprotein; Glycoprotein; Lysosome; Oxidoreductase. FT CHAIN <1 >46 L-amino-acid oxidase. FT /FTId=PRO_0000099873. FT CARBOHYD 31 31 N-linked (GlcNAc...) (Potential). FT NON_TER 1 1 FT NON_TER 46 46 SQ SEQUENCE 46 AA; 5165 MW; 483CBE1F75610164 CRC64; AFKDLKALGC KKAMNKFNKH TLLEYLLEEG NLSRPAVQLL GDVMSE //