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Protein

Citrate synthase

Gene

gltA-3

Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei281UniRule annotation1
Active sitei332UniRule annotation1

GO - Molecular functioni

  • 2-methylcitrate synthase activity Source: MTBBASE
  • citrate synthase activity Source: UniProtKB

GO - Biological processi

  • propionate catabolic process, 2-methylcitrate cycle Source: MTBBASE
  • propionate metabolic process, methylcitrate cycle Source: MTBBASE
  • response to acidic pH Source: MTBBASE
  • response to host immune response Source: MTBBASE
  • tricarboxylic acid cycle Source: InterPro

Keywordsi

Molecular functionAcyltransferaseImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Citrate synthaseUniRule annotation
Gene namesi
Name:gltA-3Imported
Ordered Locus Names:MT1163Imported
OrganismiMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)Imported
Taxonomic identifieri83331 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001020 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Structurei

3D structure databases

ProteinModelPortaliO08395
SMRiO08395
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the citrate synthase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000021225
KOiK01647
OrthoDBiPOG091H00T5

Family and domain databases

Gene3Di1.10.230.10, 1 hit
1.10.580.10, 2 hits
InterProiView protein in InterPro
IPR011278 2-MeCitrate/Citrate_synth_II
IPR016142 Citrate_synth-like_lrg_a-sub
IPR016143 Citrate_synth-like_sm_a-sub
IPR002020 Citrate_synthase
IPR019810 Citrate_synthase_AS
IPR024176 Citrate_synthase_bac-typ
IPR036969 Citrate_synthase_sf
PANTHERiPTHR11739 PTHR11739, 1 hit
PfamiView protein in Pfam
PF00285 Citrate_synt, 1 hit
PIRSFiPIRSF001369 Citrate_synth, 1 hit
PRINTSiPR00143 CITRTSNTHASE
SUPFAMiSSF48256 SSF48256, 1 hit
TIGRFAMsiTIGR01800 cit_synth_II, 1 hit
PROSITEiView protein in PROSITE
PS00480 CITRATE_SYNTHASE, 1 hit

Sequencei

Sequence statusi: Complete.

O08395-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGPLAAARS VAATKSMTAP TVDERPDIKK GLAGVVVDTT AISKVVPQTN
60 70 80 90 100
SLTYRGYPVQ DLAARCSFEQ VAFLLWRGEL PTDAELALFS QRERASRRVD
110 120 130 140 150
RSMLSLLAKL PDNCHPMDVV RTAISYLGAE DPDEDDAAAN RAKAMRMMAV
160 170 180 190 200
LPTIVAIDMR RRRGLPPIAP HSGLGYAQNF LHMCFGEVPE TAVVSAFEQS
210 220 230 240 250
MILYAEHGFN ASTFAARVVT STQSDIYSAV TGAIGALKGR LHGGANEAVM
260 270 280 290 300
HDMIEIGDPA NAREWLRAKL ARKEKIMGFG HRVYRHGDSR VPTMKRALER
310 320 330 340 350
VGTVRDGQRW LDIYQVLAAE MASATGILPN LDFPTGPAYY LMGFDIASFT
360 370 380 390
PIFVMSRITG WTAHIMEQAT ANALIRPLSA YCGHEQRVLP GTF
Length:393
Mass (Da):42,969
Last modified:July 1, 1997 - v1
Checksum:i5591E9F482CF1232
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000516 Genomic DNA Translation: AAK45420.1
PIRiD70539
RefSeqiWP_003405909.1, NZ_KK341227.1

Genome annotation databases

EnsemblBacteriaiAAK45420; AAK45420; MT1163
KEGGimtc:MT1163
PATRICifig|83331.31.peg.1258

Similar proteinsi

Entry informationi

Entry nameiO08395_MYCTO
AccessioniPrimary (citable) accession number: O08395
Secondary accession number(s): F2GGE1, Q7D8S8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: March 28, 2018
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health