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Protein

Citrate synthase

Gene

gltA-3

Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

  • propionate catabolic process, 2-methylcitrate cycle Source: MTBBASE
  • propionate metabolic process, methylcitrate cycle Source: UniProtKB
  • response to acid chemical Source: MTBBASE
  • response to host immune response Source: MTBBASE
  • tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseImported, Transferase

Enzyme and pathway databases

BioCyciMTBRV:RV1131-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Citrate synthaseUniRule annotation
Gene namesi
Name:gltA-3Imported
Ordered Locus Names:MT1163Imported
OrganismiMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)Imported
Taxonomic identifieri83331 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001020 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliO08395.
SMRiO08395. Positions 27-393.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the citrate synthase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000021225.
KOiK01647.
OrthoDBiPOG091H00T5.

Family and domain databases

Gene3Di1.10.230.10. 1 hit.
1.10.580.10. 1 hit.
InterProiIPR011278. 2-MeCitrate/Citrate_synth_II.
IPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase.
IPR019810. Citrate_synthase_AS.
IPR024176. Citrate_synthase_bac-typ.
[Graphical view]
PANTHERiPTHR11739. PTHR11739. 1 hit.
PfamiPF00285. Citrate_synt. 1 hit.
[Graphical view]
PIRSFiPIRSF001369. Citrate_synth. 1 hit.
PRINTSiPR00143. CITRTSNTHASE.
SUPFAMiSSF48256. SSF48256. 1 hit.
TIGRFAMsiTIGR01800. cit_synth_II. 1 hit.
PROSITEiPS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O08395-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGPLAAARS VAATKSMTAP TVDERPDIKK GLAGVVVDTT AISKVVPQTN
60 70 80 90 100
SLTYRGYPVQ DLAARCSFEQ VAFLLWRGEL PTDAELALFS QRERASRRVD
110 120 130 140 150
RSMLSLLAKL PDNCHPMDVV RTAISYLGAE DPDEDDAAAN RAKAMRMMAV
160 170 180 190 200
LPTIVAIDMR RRRGLPPIAP HSGLGYAQNF LHMCFGEVPE TAVVSAFEQS
210 220 230 240 250
MILYAEHGFN ASTFAARVVT STQSDIYSAV TGAIGALKGR LHGGANEAVM
260 270 280 290 300
HDMIEIGDPA NAREWLRAKL ARKEKIMGFG HRVYRHGDSR VPTMKRALER
310 320 330 340 350
VGTVRDGQRW LDIYQVLAAE MASATGILPN LDFPTGPAYY LMGFDIASFT
360 370 380 390
PIFVMSRITG WTAHIMEQAT ANALIRPLSA YCGHEQRVLP GTF
Length:393
Mass (Da):42,969
Last modified:July 1, 1997 - v1
Checksum:i5591E9F482CF1232
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000516 Genomic DNA. Translation: AAK45420.1.
PIRiD70539.

Genome annotation databases

EnsemblBacteriaiAAK45420; AAK45420; MT1163.
KEGGimtc:MT1163.
PATRICi18124321. VBIMycTub22151_1280.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000516 Genomic DNA. Translation: AAK45420.1.
PIRiD70539.

3D structure databases

ProteinModelPortaliO08395.
SMRiO08395. Positions 27-393.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK45420; AAK45420; MT1163.
KEGGimtc:MT1163.
PATRICi18124321. VBIMycTub22151_1280.

Phylogenomic databases

HOGENOMiHOG000021225.
KOiK01647.
OrthoDBiPOG091H00T5.

Enzyme and pathway databases

BioCyciMTBRV:RV1131-MONOMER.

Family and domain databases

Gene3Di1.10.230.10. 1 hit.
1.10.580.10. 1 hit.
InterProiIPR011278. 2-MeCitrate/Citrate_synth_II.
IPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase.
IPR019810. Citrate_synthase_AS.
IPR024176. Citrate_synthase_bac-typ.
[Graphical view]
PANTHERiPTHR11739. PTHR11739. 1 hit.
PfamiPF00285. Citrate_synt. 1 hit.
[Graphical view]
PIRSFiPIRSF001369. Citrate_synth. 1 hit.
PRINTSiPR00143. CITRTSNTHASE.
SUPFAMiSSF48256. SSF48256. 1 hit.
TIGRFAMsiTIGR01800. cit_synth_II. 1 hit.
PROSITEiPS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO08395_MYCTO
AccessioniPrimary (citable) accession number: O08395
Secondary accession number(s): F2GGE1, Q7D8S8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: September 7, 2016
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.