rpoS

Functionⁱ

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
DNA bindingⁱ	304 – 323	H-T-H motifUniRule annotationAdd BLAST		20

GO - Molecular functionⁱ

DNA binding Source: UniProtKB-HAMAP
sigma factor activity Source: UniProtKB-HAMAP
transcription factor activity, sequence-specific DNA binding Source: InterPro

Complete GO annotation...

GO - Biological processⁱ

response to stress Source: UniProtKB-HAMAP
transcription initiation from bacterial-type RNA polymerase promoter Source: UniProtKB-HAMAP

Complete GO annotation...

Keywordsⁱ

Molecular function	DNA-bindingUniRule annotationSAAS annotation, Sigma factorUniRule annotationSAAS annotation
Biological process	Transcription, Transcription regulation

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: RNA polymerase sigma factor RpoSUniRule annotation Alternative name(s): Sigma SUniRule annotation Sigma-38UniRule annotation
Gene namesⁱ	Name:rpoSUniRule annotationImported
Organismⁱ	Enterobacter cloacaeImported
Taxonomic identifierⁱ	550 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Enterobacter › Enterobacter cloacae complex

Subcellular locationⁱ

Cytoplasm
UniRule annotation
Automatic assertion according to rulesⁱ
- HAMAP-Rule:MF_00959

GO - Cellular componentⁱ

cytoplasm Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

CytoplasmUniRule annotation

Interactionⁱ

Subunit structureⁱ

Interacts with the RNA polymerase core enzyme.UniRule annotation

Protein-protein interaction databases

STRINGⁱ	716541.ECL_04088.

STRINGⁱ

716541.ECL_04088.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	O08372.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	134 – 147	RNA_pol_sigma70InterPro annotationAdd BLAST		14
Domainⁱ	303 – 329	RNA_pol_sigma70InterPro annotationAdd BLAST		27

Region

Feature key	Position(s)	DescriptionActions	Length
Regionⁱ	72 – 105	Sigma-70 factor domain-1UniRule annotationAdd BLAST	34
Regionⁱ	110 – 180	Sigma-70 factor domain-2UniRule annotationAdd BLAST	71
Regionⁱ	190 – 265	Sigma-70 factor domain-3UniRule annotationAdd BLAST	76
Regionⁱ	278 – 331	Sigma-70 factor domain-4UniRule annotationAdd BLAST	54

Motif

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Motifⁱ	134 – 137	Interaction with polymerase core subunit RpoCUniRule annotation		4

Phylogenomic databases

eggNOGⁱ	ENOG4105DG1. Bacteria. COG0568. LUCA.

eggNOGⁱ

ENOG4105DG1. Bacteria.
COG0568. LUCA.

Family and domain databases

Gene3Dⁱ	1.10.10.10. 2 hits.
HAMAPⁱ	MF_00959. Sigma70_RpoS. 1 hit.
InterProⁱ	View protein in InterPro IPR014284. RNA_pol_sigma-70_dom. IPR000943. RNA_pol_sigma70. IPR009042. RNA_pol_sigma70_r1_2. IPR007627. RNA_pol_sigma70_r2. IPR007624. RNA_pol_sigma70_r3. IPR007630. RNA_pol_sigma70_r4. IPR013325. RNA_pol_sigma_r2. IPR013324. RNA_pol_sigma_r3_r4. IPR012761. RNA_pol_sigma_RpoS. IPR011991. WHTH_DNA-bd_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00140. Sigma70_r1_2. 1 hit. PF04542. Sigma70_r2. 1 hit. PF04539. Sigma70_r3. 1 hit. PF04545. Sigma70_r4. 1 hit.
PRINTSⁱ	PR00046. SIGMA70FCT.
SUPFAMⁱ	SSF88659. SSF88659. 2 hits. SSF88946. SSF88946. 1 hit.
TIGRFAMsⁱ	TIGR02394. rpoS_proteo. 1 hit. TIGR02937. sigma70-ECF. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00715. SIGMA70_1. 1 hit. PS00716. SIGMA70_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

O08372-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPARVSRPGI TGRSHLMSQN TLKVHDLNED AEFDENGAEA FDEKALVEEE 
        60         70         80         90        100
PSDNDLAEEE LLSQGATQRV LDATQLYLGE IGYSPLLTAE EEVYFARRAL 
       110        120        130        140        150
RGDVASRRRM IESNLRLVVK IARRYGNRGL ALLDLIEEGN LGLIRAVEKF 
       160        170        180        190        200
DPERGFRFST YATWWIRQTI ERAIMNQTRT IRLPIHIVKE LNVYLRTARE 
       210        220        230        240        250
LSHKLDHEPS AEEIAEQLDK PVDDVSRMLR LNERITSVDT PLGGDSEKAL 
       260        270        280        290        300
LDILADEKDN GPEDTTQDDD MKQSIVKWLF ELNAKQREVL ARRFGLLGYE 
       310        320        330        340 
AATLEDVGRE IGLTRERVRQ IQVEGLRRLR EILQGQGLNI EALFRE

Length:346

Mass (Da):39,576

Last modified:August 1, 1998 - v2

Checksum:ⁱ83C9A535C7FBA8C0

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	Y13230 Genomic DNA. Translation: CAA73683.1.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

Y13230 Genomic DNA. Translation: CAA73683.1.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	Y13230 Genomic DNA. Translation: CAA73683.1.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

Y13230 Genomic DNA. Translation: CAA73683.1.

3D structure databases

ProteinModelPortalⁱ	O08372.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	716541.ECL_04088.

STRINGⁱ

716541.ECL_04088.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Phylogenomic databases

eggNOGⁱ	ENOG4105DG1. Bacteria. COG0568. LUCA.

eggNOGⁱ

ENOG4105DG1. Bacteria.
COG0568. LUCA.

Family and domain databases

Gene3Dⁱ	1.10.10.10. 2 hits.
HAMAPⁱ	MF_00959. Sigma70_RpoS. 1 hit.
InterProⁱ	View protein in InterPro IPR014284. RNA_pol_sigma-70_dom. IPR000943. RNA_pol_sigma70. IPR009042. RNA_pol_sigma70_r1_2. IPR007627. RNA_pol_sigma70_r2. IPR007624. RNA_pol_sigma70_r3. IPR007630. RNA_pol_sigma70_r4. IPR013325. RNA_pol_sigma_r2. IPR013324. RNA_pol_sigma_r3_r4. IPR012761. RNA_pol_sigma_RpoS. IPR011991. WHTH_DNA-bd_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00140. Sigma70_r1_2. 1 hit. PF04542. Sigma70_r2. 1 hit. PF04539. Sigma70_r3. 1 hit. PF04545. Sigma70_r4. 1 hit.
PRINTSⁱ	PR00046. SIGMA70FCT.
SUPFAMⁱ	SSF88659. SSF88659. 2 hits. SSF88946. SSF88946. 1 hit.
TIGRFAMsⁱ	TIGR02394. rpoS_proteo. 1 hit. TIGR02937. sigma70-ECF. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00715. SIGMA70_1. 1 hit. PS00716. SIGMA70_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	O08372_ENTCL
Accessionⁱ	O08372Primary (citable) accession number: O08372
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	July 1, 1997
	Last sequence update:	August 1, 1998
	Last modified:	November 2, 2016
	This is version 82 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB - O08372 (O08372_ENTCL)

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RNA polymerase sigma factor RpoS

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Functionⁱ

Regions

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

Interactionⁱ

Subunit structureⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Region

Motif

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Similar proteinsⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - O08372 (O08372_ENTCL)

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RNA polymerase sigma factor RpoS

rpoS

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

Motif

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ