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O08328 (GLGA_GEOSE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycogen synthase

EC=2.4.1.21
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene names
Name:glgA
OrganismGeobacillus stearothermophilus (Bacillus stearothermophilus)
Taxonomic identifier1422 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Protein attributes

Sequence length485 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484

Catalytic activity

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484

Sequence similarities

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
   Biological processGlycogen biosynthesis
   Molecular functionGlycosyltransferase
Transferase
Gene Ontology (GO)
   Biological_processglycogen biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionstarch synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 485485Glycogen synthase HAMAP-Rule MF_00484
PRO_0000188596

Sites

Binding site151ADP-glucose By similarity

Sequences

Sequence LengthMass (Da)Tools
O08328 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: AEE3338223ECCEAB

FASTA48556,244
        10         20         30         40         50         60 
MKVLFAVSEC APFAKSGGLA DVAGALPKEL RRLGIDARVM LPKYETIAPE WKKKMKKVAE 

        70         80         90        100        110        120 
LIVPVGWRRQ YCGVEELRHD GVIYYFIDNE YYFKRPQLYG HYDDGERFAY FCRAVLEVLP 

       130        140        150        160        170        180 
EIQFQPDVIH CHDWHTGMVP FLLREQYRHE LFYVDMRTVF TIHNLQFQGL FPRGILEDLL 

       190        200        210        220        230        240 
NLDGRYFTVD HLEFYGCVSF MKGALVASDL ITTVSPTYKE EIQTAYYGER LDGLLRARRD 

       250        260        270        280        290        300 
DLLGILNGID DEFYNPEADP FLTATYSVHT RERKQLNKRA LQRQFGLPEW DDVPLIAMVT 

       310        320        330        340        350        360 
RMTAQKGLDL VTCVFHEMMS EDMQLVVLGT GDWRFEQFFS QMAAAYPGKV GVYIGFHEPL 

       370        380        390        400        410        420 
AHQIYAGADL FLIPSLFEPC GLSQMIALRY GTIPIVRETG GLNDTVQSYN EITKEGNGFS 

       430        440        450        460        470        480 
FTNFNAHDML YTIRRALSFY RQPSVWEQLT ERAMRGDYSW RRSANQYKQA YEQLIKKEEH 


TLVHG 

« Hide

References

[1]"Characterization of a gene cluster for glycogen biosynthesis and a heterotetrameric ADP-glucose pyrophosphorylase from Bacillus stearothermophilus."
Takata H., Takaha T., Okada S., Takagi M., Imanaka T.
J. Bacteriol. 179:4689-4698(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: TRBE14.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D87026 Genomic DNA. Translation: BAA19591.1.

3D structure databases

ProteinModelPortalO08328.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGT5. Glycosyltransferase Family 5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00164.

Family and domain databases

HAMAPMF_00484. Glycogen_synth.
InterProIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR02095. glgA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGA_GEOSE
AccessionPrimary (citable) accession number: O08328
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 1, 1997
Last modified: February 19, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways