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Protein

Glycogen synthase

Gene

glgA

Organism
Geobacillus stearothermophilus (Bacillus stearothermophilus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.By similarity

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).

Pathway:iglycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthase (EC:2.4.1.21)
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene namesi
Name:glgA
OrganismiGeobacillus stearothermophilus (Bacillus stearothermophilus)
Taxonomic identifieri1422 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 485485Glycogen synthasePRO_0000188596Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO08328.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

O08328-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVLFAVSEC APFAKSGGLA DVAGALPKEL RRLGIDARVM LPKYETIAPE
60 70 80 90 100
WKKKMKKVAE LIVPVGWRRQ YCGVEELRHD GVIYYFIDNE YYFKRPQLYG
110 120 130 140 150
HYDDGERFAY FCRAVLEVLP EIQFQPDVIH CHDWHTGMVP FLLREQYRHE
160 170 180 190 200
LFYVDMRTVF TIHNLQFQGL FPRGILEDLL NLDGRYFTVD HLEFYGCVSF
210 220 230 240 250
MKGALVASDL ITTVSPTYKE EIQTAYYGER LDGLLRARRD DLLGILNGID
260 270 280 290 300
DEFYNPEADP FLTATYSVHT RERKQLNKRA LQRQFGLPEW DDVPLIAMVT
310 320 330 340 350
RMTAQKGLDL VTCVFHEMMS EDMQLVVLGT GDWRFEQFFS QMAAAYPGKV
360 370 380 390 400
GVYIGFHEPL AHQIYAGADL FLIPSLFEPC GLSQMIALRY GTIPIVRETG
410 420 430 440 450
GLNDTVQSYN EITKEGNGFS FTNFNAHDML YTIRRALSFY RQPSVWEQLT
460 470 480
ERAMRGDYSW RRSANQYKQA YEQLIKKEEH TLVHG
Length:485
Mass (Da):56,244
Last modified:July 1, 1997 - v1
Checksum:iAEE3338223ECCEAB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D87026 Genomic DNA. Translation: BAA19591.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D87026 Genomic DNA. Translation: BAA19591.1.

3D structure databases

ProteinModelPortaliO08328.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayiUPA00164.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Characterization of a gene cluster for glycogen biosynthesis and a heterotetrameric ADP-glucose pyrophosphorylase from Bacillus stearothermophilus."
    Takata H., Takaha T., Okada S., Takagi M., Imanaka T.
    J. Bacteriol. 179:4689-4698(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: TRBE14.

Entry informationi

Entry nameiGLGA_GEOSE
AccessioniPrimary (citable) accession number: O08328
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 1, 1997
Last modified: June 24, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.