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Protein

5'-nucleotidase SurE

Gene

surE

Organism
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.UniRule annotation

Catalytic activityi

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi8Divalent metal cationUniRule annotation1
Metal bindingi9Divalent metal cationUniRule annotation1
Metal bindingi40Divalent metal cationUniRule annotation1
Metal bindingi92Divalent metal cationUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
LigandMetal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
5'-nucleotidase SurEUniRule annotation (EC:3.1.3.5UniRule annotation)
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Name:surEUniRule annotation
Ordered Locus Names:R01533
ORF Names:SMc02063
OrganismiRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Taxonomic identifieri266834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
Proteomesi
  • UP000001976 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001118361 – 2565'-nucleotidase SurEAdd BLAST256

Interactioni

Protein-protein interaction databases

STRINGi266834.SMc02063.

Structurei

3D structure databases

ProteinModelPortaliO08248.
SMRiO08248.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SurE nucleotidase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CV2. Bacteria.
COG0496. LUCA.
HOGENOMiHOG000122501.
KOiK03787.
OMAiDCVHIAL.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiView protein in InterPro
IPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
IPR036523. SurE-like_sf.
PfamiView protein in Pfam
PF01975. SurE. 1 hit.
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.

Sequencei

Sequence statusi: Complete.

O08248-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRILLTNDDG IHAEGLSVLE RIARTISDDV WVVAPEVDQS GLAHSLTLSE
60 70 80 90 100
PLRLRPVSER RFALRGTPTD CVIMAVKKIL DRKPDLVLSG VNVGANLADD
110 120 130 140 150
VTYSGTVAGA IEGTLQGIRS IALSQAYQHA VGRDVPWDVA ETHAPALIRT
160 170 180 190 200
LMGVDLPDGT LINLNFPNCA VDAVAGVEVT SQGKLEFGLS IDERTDGRGF
210 220 230 240 250
PYFWLRFGER AGDFRSGTDI RALRDNRISV TPLKLDMTDH AAQERIAQAL

REGSVA
Length:256
Mass (Da):27,737
Last modified:May 30, 2000 - v2
Checksum:i68DEC9B9FD4B78B3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti147L → F in AAB88074 (PubMed:9304864).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U81296 Genomic DNA. Translation: AAB88074.1.
AL591688 Genomic DNA. Translation: CAC46112.1.
RefSeqiNP_385639.1. NC_003047.1.
WP_010969283.1. NC_003047.1.

Genome annotation databases

EnsemblBacteriaiCAC46112; CAC46112; SMc02063.
GeneIDi1233186.
KEGGisme:SMc02063.
PATRICifig|266834.11.peg.2956.

Similar proteinsi

Entry informationi

Entry nameiSURE_RHIME
AccessioniPrimary (citable) accession number: O08248
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: October 25, 2017
This is version 103 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families