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Protein
Submitted name:

CagA

Gene

cagA

Organism
Helicobacter pylori (Campylobacter pylori)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Protein family/group databases

TCDBi9.B.101.1.1. the cytotoxin-associated gene product (caga) family.

Names & Taxonomyi

Protein namesi
Submitted name:
CagAImported
Gene namesi
Name:cagAImported
OrganismiHelicobacter pylori (Campylobacter pylori)Imported
Taxonomic identifieri210 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Structurei

3D structure databases

ProteinModelPortaliO07910.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini864 – 992CagAInterPro annotationAdd BLAST129
Domaini978 – 1026CagAInterPro annotationAdd BLAST49
Domaini1009 – 1119CagAInterPro annotationAdd BLAST111

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili400 – 438Sequence analysisAdd BLAST39
Coiled coili607 – 645Sequence analysisAdd BLAST39
Coiled coili862 – 889Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

InterProiIPR005169. CagA.
IPR004355. IVSec_CagA.
[Graphical view]
PfamiPF03507. CagA. 3 hits.
[Graphical view]
PRINTSiPR01553. TYPE4SSCAGA.

Sequencei

Sequence statusi: Complete.

O07910-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNETIAQQP QTEAAFNPQQ FINNLQVAFL KVDNAVASYD PDQKPIVDKN
60 70 80 90 100
DRDNRQAFDG ISQLREEYSN KAIKNPTKKN QYFSDFINKS NDLINKDNLI
110 120 130 140 150
DIGSSIKSFQ KFGTQRYRIF TSWVSHQNDP SKINTRSIRN FMENIIQPPT
160 170 180 190 200
PDDKERAEFV KSAKQSFAGI IIGNQIRTDQ KFMGVFDEFL KERQEAEKNG
210 220 230 240 250
EPTGGDWLDI FLSFVFNKEQ SSDVKEAINQ EPVPHVQPDI ATTTTHIQGL
260 270 280 290 300
PPESRDLLDE RGNFSKFTLG DMEMLDVEGV ADIDPNYKFN QLLIHNNALS
310 320 330 340 350
SVLMGSHNGI EPEKVSLLFA GNGGFGAKHD WNATVGYKNQ QGDNVATLIN
360 370 380 390 400
VHMKNGSGLV IAGGEKGINN PSFYLYKEDQ LTGSQRALSQ EEIRNKIDFM
410 420 430 440 450
EFLAQNNAKL DNLSEKEKEK FQNEIEDFQK DSKAYLDALG NDRIAFVSKK
460 470 480 490 500
DPKHPALITE FGKGDLSYTL KVMGKKQTEA LDREKNVTLQ GNLKHDSVMF
510 520 530 540 550
VNYSNFKYTN ASKSPDKGVG VTNGVSHLDA GFSKVAVFNL PDLNNLAITS
560 570 580 590 600
FVRRNLENKL VTEGLSLQEA NKLIKDFLSS NKELVGKALN FNKAVADAKN
610 620 630 640 650
TGDYDEVKKA QKDLEKSLRK REHLEKEVEK KLETKSGNKN KMEAKAQANG
660 670 680 690 700
QKDKIFALIN KEANRDARAI AYSQNLKGIK RELSDKLEKI NTDLKDFSKS
710 720 730 740 750
FDEFKNGKNK DFSKAEETLK ALKGSVKDLG INPEWISKVE NLNAALNEFK
760 770 780 790 800
NGKNKDFSKV TQAKSDLENS VKDVIINQKI TDKVDNLNQA VSMAKATGGF
810 820 830 840 850
SRVEQALADL KNFSKEQLAQ QTQKNESFNV GKKSEIYQSV KNGVNGTLVG
860 870 880 890 900
NGLSGIEATA LAKNFSDIKK ELNEKFKNFN NNNNNGLENE PIYAKVNKKK
910 920 930 940 950
TGQVASPEEP IYAQVAKKVN AKIDRLNQAA SGLGGVGQAG FPLKRHDKVD
960 970 980 990 1000
DLSKVGRSVS PEPIYATIDD LGGPFPSKRH DKVDDLSKVG RSVSPEPIYA
1010 1020 1030 1040 1050
TIDDLGGPFP LKRHDKVDDL SKVGRSVSPE PIYATIDDLG GPFPSKRHDK
1060 1070 1080 1090 1100
VDDLSKVGLS RNQELAQKID NLSQAVSEAK AGFFSNLEQT IDKLKDSTKY
1110 1120 1130 1140 1150
NSVNLWVESA QKVPASLSAK LDNYATNSHT RINSNIQNGA INEKATGMLT
1160 1170 1180 1190 1200
HKNPEWLKLV NDKIVAHNVG SVPLSEYDKI GFNQKNMKDY SDSFKFSTKL
1210 1220 1230 1240
NNAVKDVKSS FTQFLANAFS TGYYSLAREN AEHGIKNVNT KGGFQKS
Length:1,247
Mass (Da):138,820
Last modified:July 1, 1997 - v1
Checksum:i172C76AE9F9BD29E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF001357 Genomic DNA. Translation: AAB58747.1.
AB003397 Genomic DNA. Translation: BAA19853.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF001357 Genomic DNA. Translation: AAB58747.1.
AB003397 Genomic DNA. Translation: BAA19853.1.

3D structure databases

ProteinModelPortaliO07910.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

TCDBi9.B.101.1.1. the cytotoxin-associated gene product (caga) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR005169. CagA.
IPR004355. IVSec_CagA.
[Graphical view]
PfamiPF03507. CagA. 3 hits.
[Graphical view]
PRINTSiPR01553. TYPE4SSCAGA.
ProtoNetiSearch...

Entry informationi

Entry nameiO07910_HELPX
AccessioniPrimary (citable) accession number: O07910
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: November 2, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.