ID   IORB_PYRKO              Reviewed;         202 AA.
AC   O07836; Q5JFI1;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   29-MAR-2005, sequence version 2.
DT   16-JUN-2009, entry version 54.
DE   RecName: Full=Indolepyruvate oxidoreductase subunit iorB;
DE            Short=IOR;
DE            EC=1.2.7.8;
DE   AltName: Full=Indolepyruvate ferredoxin oxidoreductase subunit beta;
GN   Name=iorB; OrderedLocusNames=TK0135;
OS   Pyrococcus kodakaraensis (Thermococcus kodakaraensis).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=69014;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=KOD1;
RX   MEDLINE=97324592; PubMed=9180697; DOI=10.1007/s004380050436;
RA   Siddiqui M.A., Fujiwara S., Imanaka T.;
RT   "Indolepyruvate ferredoxin oxidoreductase from Pyrococcus sp. KOD1
RT   possesses a mosaic structure showing features of various
RT   oxidoreductases.";
RL   Mol. Gen. Genet. 254:433-439(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KOD1;
RX   PubMed=15710748; DOI=10.1101/gr.3003105;
RA   Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT   "Complete genome sequence of the hyperthermophilic archaeon
RT   Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus
RT   genomes.";
RL   Genome Res. 15:352-363(2005).
CC   -!- FUNCTION: Catalyzes the ferredoxin-dependent oxidative
CC       decarboxylation of arylpyruvates.
CC   -!- CATALYTIC ACTIVITY: (Indol-3-yl)pyruvate + CoA + 2 oxidized
CC       ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO(2) + 2 reduced
CC       ferredoxin + H(+).
CC   -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC       Temperature dependence:
CC         Optimum temperature is 70 degrees Celsius;
CC   -!- SUBUNIT: Heterodimer of the iorA and iorB subunits.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA20529.1; Type=Frameshift; Positions=132, 148, 167, 176, 189;
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DR   EMBL; D86221; BAA20529.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; AP006878; BAD84324.1; -; Genomic_DNA.
DR   RefSeq; YP_182548.1; -.
DR   GeneID; 3235681; -.
DR   GenomeReviews; AP006878_GR; TK0135.
DR   KEGG; tko:TK0135; -.
DR   NMPDR; fig|69014.3.peg.303; -.
DR   HOGENOM; O07836; -.
DR   OMA; O07836; ALRYINY.
DR   BioCyc; TKOD69014:TK0135-MON; -.
DR   BRENDA; 1.2.7.8; 192130.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0043805; F:indolepyruvate ferredoxin oxidoreductase ac...; IEA:EC.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR017719; Indolepyruvate_Fd_OxRdtase_bsu.
DR   InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed.
DR   Gene3D; G3DSA:3.40.920.10; Pyrv_Fd/Flavodoxin_OxRdtase; 1.
DR   Pfam; PF01558; POR; 1.
DR   TIGRFAMs; TIGR03334; IOR_beta; 1.
PE   1: Evidence at protein level;
KW   Complete proteome; Oxidoreductase.
FT   CHAIN         1    202       Indolepyruvate oxidoreductase subunit
FT                                iorB.
FT                                /FTId=PRO_0000099936.
FT   CONFLICT    158    158       Q -> K (in Ref. 1; BAA20529).
FT   CONFLICT    188    188       A -> S (in Ref. 1; BAA20529).
SQ   SEQUENCE   202 AA;  21886 MW;  2BCB29E499855B43 CRC64;
     MKEYNIVITG VGGQGILTAA NLLGWAALRA GYKVRVGEVH GMSQRFGSVI AYVRFGEDVY
     GAMVPEGKAD VILSFEPVEA LRYINYLKKG GLVFTNARPI PPVQVSMGLA TYPTLDEMKK
     IVEEDFGGKF MAFDAEKLAM EAGNIVTTNV VLIGALSQTP GFPLSEEQIK EVIRISVPPK
     TIDVNMRAFE LGVKAAKEML GL
//