Probable lignin peroxidase LipJ - Mycobacterium tuberculosis

Preferred order of sections

Names and origin

Protein names

Submitted name:
Probable lignin peroxidase LipJ EMBL CCP44667.1

Gene names

Name:	lipJ EMBL CCP44667.1
Ordered Locus Names:	Rv1900c EMBL CCP44667.1

Organism

Mycobacterium tuberculosis [Reference proteome] [HAMAP]

Taxonomic identifier

1773 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	462 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Manganese PDB 1YBU Metal-binding PDB 1YBU
Molecular function	Oxidoreductase Peroxidase EMBL CCP44667.1
Technical term	3D-structure PDB 1YBT PDB 1YBU Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from direct assay Ref.2. Source: MTBBASE intracellular signal transduction Inferred from electronic annotation. Source: InterPro
Molecular_function	adenylate cyclase activity Inferred from direct assay Ref.2. Source: MTBBASE guanylate cyclase activity Inferred from direct assay Ref.2. Source: MTBBASE manganese ion binding Inferred from direct assay Ref.2. Source: MTBBASE peroxidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Sites

Metal binding

302

1

Manganese PDB 1YBU

Metal binding

303

1

Manganese; via carbonyl oxygen PDB 1YBU

Metal binding

306

1

Manganese PDB 1YBU

Metal binding

346

1

Manganese PDB 1YBU

Sequences

Sequence

Length

Mass (Da)

Tools

O07732 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: 6986897B78ED0BAA
Show »

FASTA

462

49,716

        10         20         30         40         50         60 
MAQAPHIHRT RYAKCGDMDI AYQVLGDGPT DLLVLPGPFV PIDSIDDEPS LYRFHRRLAS 

        70         80         90        100        110        120 
FSRVIRLDHR GVGLSSRLAA ITTLGPKFWA QDAIAVMDAV GCEQATIFAP SFHAMNGLVL 

       130        140        150        160        170        180 
AADYPERVRS LIVVNGSARP LWAPDYPVGA QVRRADPFLT VALEPDAVER GFDVLSIVAP 

       190        200        210        220        230        240 
TVAGDDVFRA WWDLAGNRAG PPSIARAVSK VIAEADVRDV LGHIEAPTLI LHRVGSTYIP 

       250        260        270        280        290        300 
VGHGRYLAEH IAGSRLVELP GTDTLYWVGD TGPMLDEIEE FITGVRGGAD AERMLATIMF 

       310        320        330        340        350        360 
TDIVGSTQHA AALGDDRWRD LLDNHDTIVC HEIQRFGGRE VNTAGDGFVA TFTSPSAAIA 

       370        380        390        400        410        420 
CADDIVDAVA ALGIEVRIGI HAGEVEVRDA SHGTDVAGVA VHIGARVCAL AGPSEVLVSS 

       430        440        450        460 
TVRDIVAGSR HRFAERGEQE LKGVPGRWRL CVLMRDDATR TR

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. Barrell B.G. Nature 393:537-544(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25618 / H37Rv.
[2]	"Origin of asymmetry in adenylyl cyclases: structures of Mycobacterium tuberculosis Rv1900c." Sinha S.C., Wetterer M., Sprang S.R., Schultz J.E., Linder J.U. EMBO J. 24:663-673(2005) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.31 ANGSTROMS) OF 291-462 IN COMPLEX WITH MANGANESE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AL123456 Genomic DNA. Translation: CCP44667.1.

RefSeq

NP_216416.1. NC_000962.3.
YP_006515303.1. NC_018143.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1YBT	X-ray	2.31	A/B/C/D	291-462	[»]
1YBU	X-ray	2.40	A/B/C/D	291-462	[»]

SMR

O07732. Positions 63-261, 291-462.

ModBase

Search...

Protein-protein interaction databases

STRING

83332.Rv1900c.

Proteomic databases

PRIDE

O07732.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

13316694.
885151.

KEGG

mtu:Rv1900c.
mtv:RVBD_1900c.

PATRIC

18152787. VBIMycTub87468_2123.

Phylogenomic databases

ProtClustDB

CLSK791471.

Family and domain databases

Gene3D

3.30.70.1230. 1 hit.

InterPro

IPR001054. A/G_cyclase.
[Graphical view]

Pfam

PF00211. Guanylate_cyc. 1 hit.
[Graphical view]

SMART

SM00044. CYCc. 1 hit.
[Graphical view]

SUPFAM

SSF55073. A/G_cyclase. 1 hit.

PROSITE

PS50125. GUANYLATE_CYCLASE_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

O07732_MYCTU

Accession

Primary (citable) accession number: O07732

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 1997
Last sequence update:	July 1, 1997
Last modified:	May 1, 2013
This is version 87 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)