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O07685 (BGAM_LACAC) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-galactosidase small subunit

Short name=Beta-gal small subunit
EC=3.2.1.23
Alternative name(s):
Lactase small subunit
Gene names
Name:lacM
Ordered Locus Names:LBA1468
OrganismLactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM) [Complete proteome] [HAMAP]
Taxonomic identifier272621 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Protein attributes

Sequence length316 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Subunit structure

Heterodimer of a large and a small subunit.

Sequence similarities

Belongs to the bacterial beta-galactosidase small subunit family.

Ontologies

Keywords
   Molecular functionGlycosidase
Hydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentbeta-galactosidase complex

Inferred from electronic annotation. Source: InterPro

   Molecular_functionbeta-galactosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

carbohydrate binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 316316Beta-galactosidase small subunit
PRO_0000057666

Sequences

Sequence LengthMass (Da)Tools
O07685 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: 897FD295D9792819

FASTA31635,817
        10         20         30         40         50         60 
MAYTNNLQII YGDATLGITG KNFHYLFSYE RGGLESLNIN NKEWLYRVPT PTFWRATTDN 

        70         80         90        100        110        120 
DRGNGFNLKA SQWLGADMFT KCTKIELKVD DRQFDELPIA PINNQFSNHE YADHVQIAFW 

       130        140        150        160        170        180 
YQTLTNPATD VKIIYNIDNT GCINIVMHYF GKKGLPPLPV IGMRFIMPTA ATGFDYEGLS 

       190        200        210        220        230        240 
GETYPDRMAG AKEGKFHVDG LPVTKYLVPQ ENGMHMQTKA LKITRSSTLN NADQESEFSL 

       250        260        270        280        290        300 
KLKQDKQPFN FSCLPYTAEE LENATHLEEL PLARRTVLVI AGAVRGVGGI DSWGADVEKQ 

       310 
YHINPEKDYE FSFNLN 

« Hide

References

« Hide 'large scale' references
[1]Suzuki M., Saito T., Konno K., Kamio Y., Itoh T.
Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: JCM 1229 / KCTC 3168.
[2]"Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM."
Altermann E., Russell W.M., Azcarate-Peril M.A., Barrangou R., Buck B.L., McAuliffe O., Souther N., Dobson A., Duong T., Callanan M., Lick S., Hamrick A., Cano R., Klaenhammer T.R.
Proc. Natl. Acad. Sci. U.S.A. 102:3906-3912(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700396 / NCK56 / N2 / NCFM.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB004868 Genomic DNA. Translation: BAA20537.1.
CP000033 Genomic DNA. Translation: AAV43288.1.
RefSeqYP_194319.1. NC_006814.3.

3D structure databases

ProteinModelPortalO07685.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272621.LBA1468.

Protein family/group databases

CAZyGH2. Glycoside Hydrolase Family 2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAV43288; AAV43288; LBA1468.
GeneID3251495.
KEGGlac:LBA1468.
PATRIC22197952. VBILacAci7974_1389.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3250.
HOGENOMHOG000111247.
KOK01190.
OMAQWLGADM.
OrthoDBEOG651SX5.

Enzyme and pathway databases

BioCycLACI272621:GJO8-2375-MONOMER.
BRENDA3.2.1.23. 2846.

Family and domain databases

Gene3D2.70.98.10. 1 hit.
InterProIPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamPF02929. Bgal_small_N. 1 hit.
[Graphical view]
SMARTSM01038. Bgal_small_N. 1 hit.
[Graphical view]
SUPFAMSSF74650. SSF74650. 1 hit.
ProtoNetSearch...

Entry information

Entry nameBGAM_LACAC
AccessionPrimary (citable) accession number: O07685
Secondary accession number(s): Q5FJ36
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: July 1, 1997
Last modified: May 14, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries