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Protein

Beta-galactosidase small subunit

Gene

lacM

Organism
Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

GO - Molecular functioni

  1. beta-galactosidase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Enzyme and pathway databases

BioCyciLACI272621:GJO8-2375-MONOMER.
BRENDAi3.2.1.23. 2846.

Protein family/group databases

CAZyiGH2. Glycoside Hydrolase Family 2.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidase small subunit (EC:3.2.1.23)
Short name:
Beta-gal small subunit
Alternative name(s):
Lactase small subunit
Gene namesi
Name:lacM
Ordered Locus Names:LBA1468
OrganismiLactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)
Taxonomic identifieri272621 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000006381: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. beta-galactosidase complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 316316Beta-galactosidase small subunitPRO_0000057666Add
BLAST

Interactioni

Subunit structurei

Heterodimer of a large and a small subunit.

Protein-protein interaction databases

STRINGi272621.LBA1468.

Structurei

3D structure databases

ProteinModelPortaliO07685.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG3250.
HOGENOMiHOG000111247.
KOiK01190.
OMAiQWLGADM.
OrthoDBiEOG651SX5.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF02929. Bgal_small_N. 1 hit.
[Graphical view]
SMARTiSM01038. Bgal_small_N. 1 hit.
[Graphical view]
SUPFAMiSSF74650. SSF74650. 1 hit.

Sequencei

Sequence statusi: Complete.

O07685-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAYTNNLQII YGDATLGITG KNFHYLFSYE RGGLESLNIN NKEWLYRVPT
60 70 80 90 100
PTFWRATTDN DRGNGFNLKA SQWLGADMFT KCTKIELKVD DRQFDELPIA
110 120 130 140 150
PINNQFSNHE YADHVQIAFW YQTLTNPATD VKIIYNIDNT GCINIVMHYF
160 170 180 190 200
GKKGLPPLPV IGMRFIMPTA ATGFDYEGLS GETYPDRMAG AKEGKFHVDG
210 220 230 240 250
LPVTKYLVPQ ENGMHMQTKA LKITRSSTLN NADQESEFSL KLKQDKQPFN
260 270 280 290 300
FSCLPYTAEE LENATHLEEL PLARRTVLVI AGAVRGVGGI DSWGADVEKQ
310
YHINPEKDYE FSFNLN
Length:316
Mass (Da):35,817
Last modified:July 1, 1997 - v1
Checksum:i897FD295D9792819
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB004868 Genomic DNA. Translation: BAA20537.1.
CP000033 Genomic DNA. Translation: AAV43288.1.
RefSeqiWP_011254473.1. NC_006814.3.
YP_194319.1. NC_006814.3.

Genome annotation databases

EnsemblBacteriaiAAV43288; AAV43288; LBA1468.
GeneIDi3251495.
KEGGilac:LBA1468.
PATRICi22197952. VBILacAci7974_1389.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB004868 Genomic DNA. Translation: BAA20537.1.
CP000033 Genomic DNA. Translation: AAV43288.1.
RefSeqiWP_011254473.1. NC_006814.3.
YP_194319.1. NC_006814.3.

3D structure databases

ProteinModelPortaliO07685.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272621.LBA1468.

Protein family/group databases

CAZyiGH2. Glycoside Hydrolase Family 2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAV43288; AAV43288; LBA1468.
GeneIDi3251495.
KEGGilac:LBA1468.
PATRICi22197952. VBILacAci7974_1389.

Phylogenomic databases

eggNOGiCOG3250.
HOGENOMiHOG000111247.
KOiK01190.
OMAiQWLGADM.
OrthoDBiEOG651SX5.

Enzyme and pathway databases

BioCyciLACI272621:GJO8-2375-MONOMER.
BRENDAi3.2.1.23. 2846.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF02929. Bgal_small_N. 1 hit.
[Graphical view]
SMARTiSM01038. Bgal_small_N. 1 hit.
[Graphical view]
SUPFAMiSSF74650. SSF74650. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Suzuki M., Saito T., Konno K., Kamio Y., Itoh T.
    Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: JCM 1229 / KCTC 3168.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700396 / NCK56 / N2 / NCFM.

Entry informationi

Entry nameiBGAM_LACAC
AccessioniPrimary (citable) accession number: O07685
Secondary accession number(s): Q5FJ36
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: July 1, 1997
Last modified: January 7, 2015
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.