Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O07621

- HEMAT_BACSU

UniProt

O07621 - HEMAT_BACSU

Protein

Heme-based aerotactic transducer HemAT

Gene

hemAT

Organism
Bacillus subtilis (strain 168)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 1 (01 Jul 1997)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Heme-containing signal transducer responsible for aerotaxis, the migratory response toward or away from oxygen.1 Publication

    GO - Molecular functioni

    1. heme binding Source: UniProtKB
    2. iron ion binding Source: InterPro
    3. oxygen binding Source: InterPro
    4. signal transducer activity Source: UniProtKB

    GO - Biological processi

    1. aerotaxis Source: UniProtKB
    2. oxygen transport Source: InterPro
    3. signal transduction Source: UniProtKB

    Keywords - Molecular functioni

    Transducer

    Keywords - Ligandi

    Heme, Iron, Metal-binding

    Enzyme and pathway databases

    BioCyciBSUB:BSU10380-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Heme-based aerotactic transducer HemAT
    Gene namesi
    Name:hemAT
    Synonyms:yhfV
    Ordered Locus Names:BSU10380
    OrganismiBacillus subtilis (strain 168)
    Taxonomic identifieri224308 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
    ProteomesiUP000001570: Chromosome

    Organism-specific databases

    GenoListiBSU10380. [Micado]

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 432432Heme-based aerotactic transducer HemATPRO_0000110567Add
    BLAST

    Proteomic databases

    PaxDbiO07621.

    Interactioni

    Subunit structurei

    Homotetramer.1 Publication

    Protein-protein interaction databases

    IntActiO07621. 3 interactions.
    STRINGi224308.BSU10380.

    Structurei

    Secondary structure

    1
    432
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi18 – 214
    Helixi29 – 313
    Helixi32 – 409
    Helixi45 – 7329
    Helixi77 – 8610
    Helixi89 – 10214
    Helixi110 – 12516
    Helixi130 – 15122
    Helixi155 – 17622

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1OR4X-ray2.15A/B1-178[»]
    1OR6X-ray2.71A/B1-178[»]
    ProteinModelPortaliO07621.
    SMRiO07621. Positions 10-178, 209-412.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiO07621.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini184 – 420237Methyl-accepting transducerPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 methyl-accepting transducer domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0840.
    HOGENOMiHOG000099831.
    KOiK06595.
    OMAiDHESSLM.
    OrthoDBiEOG6QG8FJ.
    PhylomeDBiO07621.

    Family and domain databases

    Gene3Di1.10.490.10. 1 hit.
    InterProiIPR009050. Globin-like.
    IPR012292. Globin_dom.
    IPR004089. MCPsignal_dom.
    [Graphical view]
    PfamiPF00015. MCPsignal. 1 hit.
    [Graphical view]
    SMARTiSM00283. MA. 1 hit.
    [Graphical view]
    SUPFAMiSSF46458. SSF46458. 1 hit.
    PROSITEiPS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O07621-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLFKKDRKQE TAYFSDSNGQ QKNRIQLTNK HADVKKQLKM VRLGDAELYV    50
    LEQLQPLIQE NIVNIVDAFY KNLDHESSLM DIINDHSSVD RLKQTLKRHI 100
    QEMFAGVIDD EFIEKRNRIA SIHLRIGLLP KWYMGAFQEL LLSMIDIYEA 150
    SITNQQELLK AIKATTKILN LEQQLVLEAF QSEYNQTRDE QEEKKNLLHQ 200
    KIQETSGSIA NLFSETSRSV QELVDKSEGI SQASKAGTVT SSTVEEKSIG 250
    GKKELEVQQK QMNKIDTSLV QIEKEMVKLD EIAQQIEKIF GIVTGIAEQT 300
    NLLSLNASIE SARAGEHGKG FAVVANEVRK LSEDTKKTVS TVSELVNNTN 350
    TQINIVSKHI KDVNELVSES KEKMTQINRL FDEIVHSMKI SKEQSGKIDV 400
    DLQAFLGGLQ EVSRAVSHVA ASVDSLVILT EE 432
    Length:432
    Mass (Da):48,767
    Last modified:July 1, 1997 - v1
    Checksum:i87D0655974070B64
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y14084 Genomic DNA. Translation: CAA74545.1.
    AL009126 Genomic DNA. Translation: CAB12878.1.
    PIRiC69832.
    RefSeqiNP_388919.1. NC_000964.3.

    Genome annotation databases

    EnsemblBacteriaiCAB12878; CAB12878; BSU10380.
    GeneIDi936320.
    KEGGibsu:BSU10380.
    PATRICi18973778. VBIBacSub10457_1083.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y14084 Genomic DNA. Translation: CAA74545.1 .
    AL009126 Genomic DNA. Translation: CAB12878.1 .
    PIRi C69832.
    RefSeqi NP_388919.1. NC_000964.3.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1OR4 X-ray 2.15 A/B 1-178 [» ]
    1OR6 X-ray 2.71 A/B 1-178 [» ]
    ProteinModelPortali O07621.
    SMRi O07621. Positions 10-178, 209-412.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi O07621. 3 interactions.
    STRINGi 224308.BSU10380.

    Proteomic databases

    PaxDbi O07621.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAB12878 ; CAB12878 ; BSU10380 .
    GeneIDi 936320.
    KEGGi bsu:BSU10380.
    PATRICi 18973778. VBIBacSub10457_1083.

    Organism-specific databases

    GenoListi BSU10380. [Micado ]

    Phylogenomic databases

    eggNOGi COG0840.
    HOGENOMi HOG000099831.
    KOi K06595.
    OMAi DHESSLM.
    OrthoDBi EOG6QG8FJ.
    PhylomeDBi O07621.

    Enzyme and pathway databases

    BioCyci BSUB:BSU10380-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei O07621.

    Family and domain databases

    Gene3Di 1.10.490.10. 1 hit.
    InterProi IPR009050. Globin-like.
    IPR012292. Globin_dom.
    IPR004089. MCPsignal_dom.
    [Graphical view ]
    Pfami PF00015. MCPsignal. 1 hit.
    [Graphical view ]
    SMARTi SM00283. MA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46458. SSF46458. 1 hit.
    PROSITEi PS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The 172 kb prkA-addAB region from 83 degrees to 97 degrees of the Bacillus subtilis chromosome contains several dysfunctional genes, the glyB marker, many genes encoding transporter proteins, and the ubiquitous hit gene."
      Noback M.A., Holsappel S., Kiewiet R., Terpstra P., Wambutt R., Wedler H., Venema G., Bron S.
      Microbiology 144:859-875(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: 168.
    2. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
      Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
      , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
      Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 168.
    3. "Myoglobin-like aerotaxis transducers in Archaea and Bacteria."
      Hou S., Larsen R.W., Boudko D., Riley C.W., Karatan E., Zimmer M., Ordal G.W., Alam M.
      Nature 403:540-544(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    4. "Resonance Raman and ligand binding studies of the oxygen-sensing signal transducer protein HemAT from Bacillus subtilis."
      Aono S., Kato T., Matsuki M., Nakajima H., Ohta T., Uchida T., Kitagawa T.
      J. Biol. Chem. 277:13528-13538(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: RESONANCE RAMAN SPECTROSCOPY, SUBUNIT.

    Entry informationi

    Entry nameiHEMAT_BACSU
    AccessioniPrimary (citable) accession number: O07621
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 6, 2002
    Last sequence update: July 1, 1997
    Last modified: October 1, 2014
    This is version 95 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Bacillus subtilis
      Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3