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Protein

Putative quinone oxidoreductase YhfP

Gene

yhfP

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei45 – 451NADP; via amide nitrogenBy similarity
Binding sitei202 – 2021NADPBy similarity
Binding sitei248 – 2481NADP; via amide nitrogenBy similarity
Binding sitei262 – 2621NADP; via carbonyl oxygenBy similarity
Binding sitei273 – 2731NADPBy similarity
Binding sitei320 – 3201NADPBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi160 – 1634NADPBy similarity
Nucleotide bindingi182 – 1843NADPBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NADP

Enzyme and pathway databases

BioCyciBSUB:BSU10320-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative quinone oxidoreductase YhfP (EC:1.6.5.-)
Gene namesi
Name:yhfP
Ordered Locus Names:BSU10320
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 330330Putative quinone oxidoreductase YhfPPRO_0000360861Add
BLAST

Proteomic databases

PaxDbiO07615.

Interactioni

Subunit structurei

Homodimer, or homotetramer.1 Publication

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100005726.

Structurei

Secondary structure

1
330
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi4 – 107Combined sources
Helixi13 – 153Combined sources
Beta strandi20 – 2910Combined sources
Beta strandi31 – 388Combined sources
Beta strandi41 – 433Combined sources
Helixi45 – 506Combined sources
Beta strandi62 – 643Combined sources
Beta strandi67 – 759Combined sources
Beta strandi86 – 916Combined sources
Turni95 – 973Combined sources
Beta strandi101 – 1088Combined sources
Helixi110 – 1123Combined sources
Beta strandi113 – 1153Combined sources
Helixi122 – 14423Combined sources
Helixi149 – 1513Combined sources
Beta strandi154 – 1585Combined sources
Helixi162 – 17413Combined sources
Beta strandi178 – 1869Combined sources
Helixi188 – 1947Combined sources
Beta strandi197 – 2015Combined sources
Helixi202 – 2054Combined sources
Beta strandi218 – 2247Combined sources
Helixi228 – 2347Combined sources
Beta strandi237 – 2459Combined sources
Beta strandi254 – 2563Combined sources
Helixi259 – 2624Combined sources
Beta strandi267 – 2704Combined sources
Beta strandi273 – 2753Combined sources
Helixi278 – 28710Combined sources
Turni288 – 2914Combined sources
Beta strandi300 – 3056Combined sources
Helixi307 – 3093Combined sources
Helixi310 – 3167Combined sources
Turni317 – 3204Combined sources
Beta strandi323 – 3286Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TT7X-ray2.70A/B/C/D/E/F1-330[»]
1Y9EX-ray2.80A/B/C/D/E/F1-330[»]
ProteinModelPortaliO07615.
SMRiO07615. Positions 2-330.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO07615.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0604. LUCA.
HOGENOMiHOG000294662.
InParanoidiO07615.
OMAiETEWGGY.
OrthoDBiEOG6V4G9J.
PhylomeDBiO07615.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.180.10. 1 hit.
InterProiIPR014188. Acrylyl-CoA_reductase_AcuI.
IPR013149. ADH_C.
IPR013154. ADH_N.
IPR002085. ADH_SF_Zn-type.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
IPR020843. PKS_ER.
[Graphical view]
PANTHERiPTHR11695. PTHR11695. 1 hit.
PTHR11695:SF13. PTHR11695:SF13. 1 hit.
PfamiPF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
[Graphical view]
SMARTiSM00829. PKS_ER. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR02823. oxido_YhdH. 1 hit.

Sequencei

Sequence statusi: Complete.

O07615-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTLFQALQA EKNADDVSVH VKTISTEDLP KDGVLIKVAY SGINYKDGLA
60 70 80 90 100
GKAGGNIVRE YPLILGIDAA GTVVSSNDPR FAEGDEVIAT SYELGVSRDG
110 120 130 140 150
GLSEYASVPG DWLVPLPQNL SLKEAMVYGT AGFTAALSVH RLEQNGLSPE
160 170 180 190 200
KGSVLVTGAT GGVGGIAVSM LNKRGYDVVA STGNREAADY LKQLGASEVI
210 220 230 240 250
SREDVYDGTL KALSKQQWQG AVDPVGGKQL ASLLSKIQYG GSVAVSGLTG
260 270 280 290 300
GGEVPATVYP FILRGVSLLG IDSVYCPMDV RAAVWERMSS DLKPDQLLTI
310 320 330
VDREVSLEET PGALKDILQN RIQGRVIVKL
Length:330
Mass (Da):34,756
Last modified:July 1, 1997 - v1
Checksum:i4B864054355D055C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y14084 Genomic DNA. Translation: CAA74539.1.
AL009126 Genomic DNA. Translation: CAB12872.1.
PIRiE69831.
RefSeqiNP_388913.1. NC_000964.3.
WP_003233163.1. NZ_JNCM01000035.1.

Genome annotation databases

EnsemblBacteriaiCAB12872; CAB12872; BSU10320.
GeneIDi939312.
KEGGibsu:BSU10320.
PATRICi18973764. VBIBacSub10457_1076.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y14084 Genomic DNA. Translation: CAA74539.1.
AL009126 Genomic DNA. Translation: CAB12872.1.
PIRiE69831.
RefSeqiNP_388913.1. NC_000964.3.
WP_003233163.1. NZ_JNCM01000035.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TT7X-ray2.70A/B/C/D/E/F1-330[»]
1Y9EX-ray2.80A/B/C/D/E/F1-330[»]
ProteinModelPortaliO07615.
SMRiO07615. Positions 2-330.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100005726.

Proteomic databases

PaxDbiO07615.

Protocols and materials databases

DNASUi939312.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB12872; CAB12872; BSU10320.
GeneIDi939312.
KEGGibsu:BSU10320.
PATRICi18973764. VBIBacSub10457_1076.

Phylogenomic databases

eggNOGiCOG0604. LUCA.
HOGENOMiHOG000294662.
InParanoidiO07615.
OMAiETEWGGY.
OrthoDBiEOG6V4G9J.
PhylomeDBiO07615.

Enzyme and pathway databases

BioCyciBSUB:BSU10320-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO07615.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.180.10. 1 hit.
InterProiIPR014188. Acrylyl-CoA_reductase_AcuI.
IPR013149. ADH_C.
IPR013154. ADH_N.
IPR002085. ADH_SF_Zn-type.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
IPR020843. PKS_ER.
[Graphical view]
PANTHERiPTHR11695. PTHR11695. 1 hit.
PTHR11695:SF13. PTHR11695:SF13. 1 hit.
PfamiPF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
[Graphical view]
SMARTiSM00829. PKS_ER. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR02823. oxido_YhdH. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Noback M.A., Terpstra P., Holsappel S., Venema G., Bron S.
    Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168.
  2. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
    Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
    , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
    Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 168.
  3. "The structural study of hypothetical protein yhfP."
    New York structural genomix research consortium (NYSGXRC)
    Submitted (JAN-2005) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) IN COMPLEX WITH NAD, SUBUNIT.

Entry informationi

Entry nameiYHFP_BACSU
AccessioniPrimary (citable) accession number: O07615
Secondary accession number(s): Q796T7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: July 1, 1997
Last modified: May 11, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.