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Protein

Proton/sodium-glutamate symport protein

Gene

gltT

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

This carrier protein is part of the Na+-dependent, binding-protein-independent glutamate-aspartate transport system.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Symport, Transport

Enzyme and pathway databases

BioCyciBSUB:BSU10220-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Proton/sodium-glutamate symport protein
Alternative name(s):
Glutamate-aspartate carrier protein
Gene namesi
Name:gltT
Synonyms:yhfG
Ordered Locus Names:BSU10220
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 5CytoplasmicSequence analysis5
Transmembranei6 – 26HelicalSequence analysisAdd BLAST21
Topological domaini27 – 45ExtracellularSequence analysisAdd BLAST19
Transmembranei46 – 66HelicalSequence analysisAdd BLAST21
Topological domaini67 – 79CytoplasmicSequence analysisAdd BLAST13
Transmembranei80 – 100HelicalSequence analysisAdd BLAST21
Topological domaini101 – 150ExtracellularSequence analysisAdd BLAST50
Transmembranei151 – 171HelicalSequence analysisAdd BLAST21
Topological domaini172 – 190CytoplasmicSequence analysisAdd BLAST19
Transmembranei191 – 211HelicalSequence analysisAdd BLAST21
Topological domaini212 – 224ExtracellularSequence analysisAdd BLAST13
Transmembranei225 – 245HelicalSequence analysisAdd BLAST21
Topological domaini246CytoplasmicSequence analysis1
Transmembranei247 – 267HelicalSequence analysisAdd BLAST21
Topological domaini268 – 290ExtracellularSequence analysisAdd BLAST23
Transmembranei291 – 311HelicalSequence analysisAdd BLAST21
Topological domaini312 – 321CytoplasmicSequence analysis10
Transmembranei322 – 342HelicalSequence analysisAdd BLAST21
Topological domaini343 – 353ExtracellularSequence analysisAdd BLAST11
Transmembranei354 – 374HelicalSequence analysisAdd BLAST21
Topological domaini375 – 429CytoplasmicSequence analysisAdd BLAST55

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003606661 – 429Proton/sodium-glutamate symport proteinAdd BLAST429

Proteomic databases

PaxDbiO07605.

Interactioni

Subunit structurei

Homotrimer.By similarity

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100005676.

Structurei

3D structure databases

ProteinModelPortaliO07605.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1301. LUCA.
HOGENOMiHOG000208778.
InParanoidiO07605.
KOiK11102.
OMAiAKADQNA.
PhylomeDBiO07605.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
InterProiIPR033380. GltP/GltT.
IPR001991. Na-dicarboxylate_symporter.
IPR018107. Na-dicarboxylate_symporter_CS.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PTHR11958:SF26. PTHR11958:SF26. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 1 hit.
PROSITEiPS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O07605-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRIKFGLAT QIFVGLILGV IVGVIWYGNP ALPTYLQPIG DLFLRLIKMI
60 70 80 90 100
VIPIVVSSLI IGVAGAGNGK QVGKLGFRTI LYFEIITTFA IILGLALANI
110 120 130 140 150
FHPGTGVNIH EAQKSDISQY VETEKEQSNK SVAETFLHIV PTNFFQSLVE
160 170 180 190 200
GDLLAIICFT VLFALGISAI GERGKPVLAF FEGVSHAMFH VVNLVMKVAP
210 220 230 240 250
FGVFALIGVT VSKFGLGSLI SLGKLVGLVY VALAFFLIVI FGIVAKIAGI
260 270 280 290 300
SIFKFLAYMK DEILLAFSTS SSETVLPRIM EKMEKIGCPK GIVSFVIPIG
310 320 330 340 350
YTFNLDGSVL YQSIAALFLA QVYGIDLTIW HQITLVLVLM VTSKGMAAVP
360 370 380 390 400
GTSFVVLLAT LGTIGVPAEG LAFIAGVDRI MDMARTVVNL TGNALAAVVM
410 420
SKWEGMFNPA KAETVMSQSK TEQNATISG
Length:429
Mass (Da):45,920
Last modified:July 1, 1997 - v1
Checksum:i0B70931EF10F9993
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y14083 Genomic DNA. Translation: CAA74528.1.
AL009126 Genomic DNA. Translation: CAB12862.1.
PIRiD69635.
RefSeqiNP_388903.1. NC_000964.3.
WP_003245579.1. NZ_JNCM01000035.1.

Genome annotation databases

EnsemblBacteriaiCAB12862; CAB12862; BSU10220.
GeneIDi939770.
KEGGibsu:BSU10220.
PATRICi18973742. VBIBacSub10457_1065.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y14083 Genomic DNA. Translation: CAA74528.1.
AL009126 Genomic DNA. Translation: CAB12862.1.
PIRiD69635.
RefSeqiNP_388903.1. NC_000964.3.
WP_003245579.1. NZ_JNCM01000035.1.

3D structure databases

ProteinModelPortaliO07605.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100005676.

Proteomic databases

PaxDbiO07605.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB12862; CAB12862; BSU10220.
GeneIDi939770.
KEGGibsu:BSU10220.
PATRICi18973742. VBIBacSub10457_1065.

Phylogenomic databases

eggNOGiCOG1301. LUCA.
HOGENOMiHOG000208778.
InParanoidiO07605.
KOiK11102.
OMAiAKADQNA.
PhylomeDBiO07605.

Enzyme and pathway databases

BioCyciBSUB:BSU10220-MONOMER.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
InterProiIPR033380. GltP/GltT.
IPR001991. Na-dicarboxylate_symporter.
IPR018107. Na-dicarboxylate_symporter_CS.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PTHR11958:SF26. PTHR11958:SF26. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 1 hit.
PROSITEiPS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLTT_BACSU
AccessioniPrimary (citable) accession number: O07605
Secondary accession number(s): Q796U4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: July 1, 1997
Last modified: October 5, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.