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Protein
Submitted name:

Beta-glucosidase

Gene

bglS

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Beta-glucosidaseImported
Submitted name:
Beta-glucosidase BglSImported
Submitted name:
Probable beta-glucosidase BglS (Gentiobiase) (Cellobiase) (Beta-D-glucoside glucohydrolase)Imported
Gene namesi
Name:bglSImported
Ordered Locus Names:Rv0186Imported, RVBD_0186Imported
ORF Names:LH57_01030Imported, P425_00193Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000001584: Chromosome, UP000003123: Chromosome

Organism-specific databases

TubercuListiRv0186.

Subcellular locationi

GO - Cellular componenti

  1. plasma membrane Source: MTBBASE
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv0186.

Structurei

3D structure databases

ProteinModelPortaliO07430.
SMRiO07430. Positions 1-684.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK05349.
OMAiDYATAMP.
OrthoDBiEOG6N9468.
PhylomeDBiO07430.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 1 hit.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSiPR00133. GLHYDRLASE3.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.

Sequencei

Sequence statusi: Complete.

O07430-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTDDERFSLL VGLTGASDLW PVRDERIPQG VPMCAGYVPG IPRLGVPALL
60 70 80 90 100
MSDAGLGVTN PGYRPGDTAT ALPAGLALAA SFNPVLARSS GKAIGREARS
110 120 130 140 150
RGFNVQLAGA INLARDPRNG RNFEYLSEDP LLSATMAAES IIGIQQQGVI
160 170 180 190 200
ATTKHFSLNC NETNRHWLDA VIDPDAHRES DLLAFEIVIE RSQPGAVMAA
210 220 230 240 250
YNKVNGDYAA GNDHLLNDVL KGAWGYRGWV MSDWGGTPSW ECALAGLDQE
260 270 280 290 300
CGAQIDAVLW QSEAFTDRLR AAYADGNLPK GRLSDMVRRI LRSMFAVGID
310 320 330 340 350
RWKPAPAPDM NAHNEIAAQM ARQGIVLLQN RGLLPLAPES AGRIAVIGGY
360 370 380 390 400
AHLGVPAGYG SSAVTPPGGY AGVIPIGGSG LAAGLRNLYL LPSSPLSELR
410 420 430 440 450
KRLPNAQFEF DPGINPAEAV LAARRADIAI VFAIRAEGEG FDSADLSLPW
460 470 480 490 500
GQDALIAAVA SANANTVVVL ETGNPVTMPW RDSVNAIMQA WYPGQAGGQA
510 520 530 540 550
VAEIVTGQVN PSGRLPITFP VDLGQTPRSQ PPELGAPWGT STTIHYTEGA
560 570 580 590 600
DVGYRWFAST NQTPMFAFGH GLSYTSFEYR DLVVTGGHTV HASFSVTNTG
610 620 630 640 650
DRSGADVPQL YMIAAPGESR LRLLGFERVE LEPGQTRRVR IEADPRLLAR
660 670 680 690
YDGEARSWRI EPGGYTVAVG ASAVALKLAA KVKLAGRGFG R
Length:691
Mass (Da):73,520
Last modified:July 1, 1997 - v1
Checksum:iB700C8C37F24E1F7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003248 Genomic DNA. Translation: AFN48035.1.
CP009480 Genomic DNA. Translation: AIR12909.1.
AL123456 Genomic DNA. Translation: CCP42912.1.
JLDD01000001 Genomic DNA. Translation: KBJ41293.1.
RefSeqiNP_214700.1. NC_000962.3.
YP_006513506.1. NC_018143.2.

Genome annotation databases

EnsemblBacteriaiAFN48035; AFN48035; RVBD_0186.
CCP42912; CCP42912; Rv0186.
KBJ41293; KBJ41293; P425_00193.
GeneIDi13316170.
886780.
KEGGimtu:Rv0186.
mtv:RVBD_0186.
PATRICi18122155. VBIMycTub22151_0212.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003248 Genomic DNA. Translation: AFN48035.1.
CP009480 Genomic DNA. Translation: AIR12909.1.
AL123456 Genomic DNA. Translation: CCP42912.1.
JLDD01000001 Genomic DNA. Translation: KBJ41293.1.
RefSeqiNP_214700.1. NC_000962.3.
YP_006513506.1. NC_018143.2.

3D structure databases

ProteinModelPortaliO07430.
SMRiO07430. Positions 1-684.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv0186.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFN48035; AFN48035; RVBD_0186.
CCP42912; CCP42912; Rv0186.
KBJ41293; KBJ41293; P425_00193.
GeneIDi13316170.
886780.
KEGGimtu:Rv0186.
mtv:RVBD_0186.
PATRICi18122155. VBIMycTub22151_0212.

Organism-specific databases

TubercuListiRv0186.

Phylogenomic databases

KOiK05349.
OMAiDYATAMP.
OrthoDBiEOG6N9468.
PhylomeDBiO07430.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 1 hit.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSiPR00133. GLHYDRLASE3.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37RvImported and H37RvImported.
  2. "Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv."
    Camus J.C., Pryor M.J., Medigue C., Cole S.T.
    Microbiology 148:2967-2973(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  5. Lew J.M.
    Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37RvImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  9. "Phylogenetic analysis of Mycobacterial species using whole genome sequences."
    Hazbon M.H., Riojas M.A., Damon A.M., Alalade R.O., Cantwell B.J., Monaco A., King S., Sohrabi A.
    Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.

Entry informationi

Entry nameiO07430_MYCTU
AccessioniPrimary (citable) accession number: O07430
Secondary accession number(s): F2GLY4, I6Y734, Q7DAB2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: February 4, 2015
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.