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Protein
Submitted name:

Mammalian cell entry protein

Gene

mce1C

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • growth of symbiont in host Source: MTBBASE
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Mammalian cell entry proteinImported
Submitted name:
Mce-family protein Mce1CImported
Gene namesi
Name:mce1CImported
Ordered Locus Names:Rv0171Imported
ORF Names:LH57_00955Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome
  • UP000031768 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  • extracellular region Source: MTBBASE
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv0171.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini40 – 11273MlaDInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiCOG1463. LUCA.
HOGENOMiHOG000044444.
KOiK02067.
OMAiIDPEDFW.
OrthoDBiEOG6WQD3C.
PhylomeDBiO07415.

Family and domain databases

InterProiIPR005693. Mce.
IPR003399. Mce/MlaD.
[Graphical view]
PfamiPF02470. MlaD. 1 hit.
[Graphical view]
PRINTSiPR01782. MCEVIRFACTOR.
TIGRFAMsiTIGR00996. Mtu_fam_mce. 1 hit.

Sequencei

Sequence statusi: Complete.

O07415-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTLEPPNRM RIGLMGIVVA LLVVAVGQSF TSVPMLFAKP SYYGQFTDSG
60 70 80 90 100
GLHKGDRVRI AGLGVGTVEG LKIDGDHIVV KFSIGTNTIG TESRLAIRTD
110 120 130 140 150
TILGRKVLEI EPRGAQALPP GGVLPVGQST TPYQIYDAFF DVTKAASGWD
160 170 180 190 200
IETVKRSLNV LSETVDQTYP HLSAALDGVA KFSDTIGKRD EQITHLLAQA
210 220 230 240 250
NQVASILGDR SEQVDRLLVN AKTLIAAFNE RGRAVDALLG NISAFSAQVQ
260 270 280 290 300
NLINDNPNLN HVLEQLRILT DLLVDRKEDL AETLTILGRF SASFGETFAS
310 320 330 340 350
GPYFKVLLAN LVPGQILQPF VDAAFKKRGI SPEDFWRSAG LPAYRWPDPN
360 370 380 390 400
GTRFPNGAPP PPPPVLEGTP EHPGPAVPPG SPCSYTPPAD GLPRPWDPLP
410 420 430 440 450
CANLTQGPFG GPDFPAPLDV ATSPPNPDGP PPAPGLPIAG RPGEVPPNVP
460 470 480 490 500
GTPVPIPQEA PPGARTLPLG PAPGPAPPPA APGPPAPPGP GPQLPAPFIN
510
PGGTGGSGVT GGSEN
Length:515
Mass (Da):53,817
Last modified:July 1, 1997 - v1
Checksum:iA740A4B45F7DD943
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR12894.1.
AL123456 Genomic DNA. Translation: CCP42897.1.
RefSeqiNP_214685.1. NC_000962.3.
WP_003901818.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiAIR12894; AIR12894; LH57_00955.
CCP42897; CCP42897; Rv0171.
GeneIDi886808.
KEGGimtu:Rv0171.
mtv:RVBD_0171.
PATRICi18148884. VBIMycTub87468_0195.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR12894.1.
AL123456 Genomic DNA. Translation: CCP42897.1.
RefSeqiNP_214685.1. NC_000962.3.
WP_003901818.1. NZ_KK339370.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv0171.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIR12894; AIR12894; LH57_00955.
CCP42897; CCP42897; Rv0171.
GeneIDi886808.
KEGGimtu:Rv0171.
mtv:RVBD_0171.
PATRICi18148884. VBIMycTub87468_0195.

Phylogenomic databases

eggNOGiCOG1463. LUCA.
HOGENOMiHOG000044444.
KOiK02067.
OMAiIDPEDFW.
OrthoDBiEOG6WQD3C.
PhylomeDBiO07415.

Family and domain databases

InterProiIPR005693. Mce.
IPR003399. Mce/MlaD.
[Graphical view]
PfamiPF02470. MlaD. 1 hit.
[Graphical view]
PRINTSiPR01782. MCEVIRFACTOR.
TIGRFAMsiTIGR00996. Mtu_fam_mce. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37RvImported and H37RvImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. "Phylogenetic analysis of Mycobacterial species using whole genome sequences."
    Hazbon M.H., Riojas M.A., Damon A.M., Alalade R.O., Cantwell B.J., Monaco A., King S., Sohrabi A.
    Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27294 / TMC 102 / H37RvImported and H37RvImported.

Entry informationi

Entry nameiO07415_MYCTU
AccessioniPrimary (citable) accession number: O07415
Secondary accession number(s): F2GLW9, I6Y722
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: May 11, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.