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Protein

Flagellum-specific ATP synthase

Gene

fliI

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.

Catalytic activityi

ATP + H2O + H+(In) = ADP + phosphate + H+(Out).PROSITE-ProRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi164 – 171ATPSequence analysis8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processATP synthesis, Bacterial flagellum biogenesis, Bacterial flagellum protein export, Hydrogen ion transport, Ion transport, Protein transport, Transport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHPY:HP1420-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellum-specific ATP synthase (EC:3.6.3.14)
Gene namesi
Name:fliI
Ordered Locus Names:HP_1420
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000429 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001446961 – 434Flagellum-specific ATP synthaseAdd BLAST434

Proteomic databases

PaxDbiO07025

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
HP_0353O251204EBI-957989,EBI-958087

Protein-protein interaction databases

DIPiDIP-3391N
IntActiO07025, 1 interactor
MINTiO07025
STRINGi85962.HP1420

Structurei

3D structure databases

ProteinModelPortaliO07025
SMRiO07025
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.Curated

Phylogenomic databases

eggNOGiENOG4108JIR Bacteria
COG1157 LUCA
KOiK02412
OMAiMDSATRF

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR020003 ATPase_a/bsu_AS
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR032463 ATPase_T3SS_FliI
IPR005714 ATPase_T3SS_FliI/YscN
IPR027417 P-loop_NTPase
PANTHERiPTHR15184:SF9 PTHR15184:SF9, 1 hit
PfamiView protein in Pfam
PF00006 ATP-synt_ab, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR01026 fliI_yscN, 1 hit
PROSITEiView protein in PROSITE
PS00152 ATPASE_ALPHA_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

O07025-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLKSLKNRL NQHFDLSPRY GSVKKIMPNI VYADGFNPSV GDVVKIEKSD
60 70 80 90 100
GSECVGMVVV AEKEQFGFTP FNFIEGARAG DKVLFLKEGL NFPVGRNLLG
110 120 130 140 150
RVLNPLGQVI DNKGALDYER LAPVITTPIA PLKRGLIDEI FSVGVKSIDG
160 170 180 190 200
LLTCGKGQKL GIFAGSGVGK STLMGMITRG CLAPIKVIAL IGERGREIPE
210 220 230 240 250
FIEKNLKGDL SSCVLVVATS DDSPLMRKYG AFCAMSVAEY FKNQGLDVLF
260 270 280 290 300
IMDSVTRFAM AQREIGLALG EPPTSKGYPP SALSLLPQLM ERAGKEENKG
310 320 330 340 350
SITAFFSVLV EGDDLSDPIA DQTRSILDGH IVLSRELTDY GIYPPINILN
360 370 380 390 400
SASRVAKDII SESQNLCARK FRRLYALLKE NEMLIRIGSY QMGNDKELDE
410 420 430
AIKKKALMEQ FLAQDENALQ PFETSFQQLE EILR
Length:434
Mass (Da):47,636
Last modified:November 1, 1997 - v2
Checksum:i6F04D67C988B4E22
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti15D → E in CAA69911 (PubMed:9231413).Curated1
Sequence conflicti115A → V in CAA69911 (PubMed:9231413).Curated1
Sequence conflicti140I → V in CAA69911 (PubMed:9231413).Curated1
Sequence conflicti323T → A in CAA69911 (PubMed:9231413).Curated1
Sequence conflicti367C → Y in CAA69911 (PubMed:9231413).Curated1
Sequence conflicti424T → Q in CAA69911 (PubMed:9231413).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y08620 Genomic DNA Translation: CAA69911.1
AE000511 Genomic DNA Translation: AAD08462.1
PIRiD64697
RefSeqiNP_208211.1, NC_000915.1
WP_001128709.1, NC_018939.1

Genome annotation databases

EnsemblBacteriaiAAD08462; AAD08462; HP_1420
GeneIDi899875
KEGGiheo:C694_07345
hpy:HP1420
PATRICifig|85962.47.peg.1524

Similar proteinsi

Entry informationi

Entry nameiFLII_HELPY
AccessioniPrimary (citable) accession number: O07025
Secondary accession number(s): P94822
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: April 25, 2018
This is version 131 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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