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O07014 (RSBP_BACSU) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 112. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoserine phosphatase RsbP

EC=3.1.3.3
Gene names
Name:rsbP
Synonyms:yvfP
Ordered Locus Names:BSU34110
OrganismBacillus subtilis (strain 168) [Reference proteome] [HAMAP]
Taxonomic identifier224308 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length403 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Positive regulator of sigma-B activity. Dephosphorylates RsbV in response to energy stress.

Catalytic activity

O-phospho-L(or D)-serine + H2O = L(or D)-serine + phosphate.

Cofactor

Manganese.

Induction

Induced by entry into stationary phase, but not by carbon and energy starvation.

Domain

The PAS domain may participate in sensing the overall energy level of the cell and communicate this information to the phosphatase domain.

Sequence similarities

Contains 1 PAS (PER-ARNT-SIM) domain.

Contains 1 PP2C-like domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 403403Phosphoserine phosphatase RsbP
PRO_0000057789

Regions

Domain1 – 4242PAS

Sequences

Sequence LengthMass (Da)Tools
O07014 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: 104A3651F7FC7962

FASTA40346,030
        10         20         30         40         50         60 
MDKQLNDAPC GFLALSEEGS IIAANRTLIK ILDYEPEQVI GQHMNMMLTI PAQLFCQLYF 

        70         80         90        100        110        120 
FPLLKLEHHI EEIYISLKAR DGEEIPVLIN AIARHDSGAS VFDCVLIPMR KRNEYENELL 

       130        140        150        160        170        180 
IARNEAQEAL LAKQKANAEL EIALETLKAK QEELLEINKQ NQQFKLNTKR ELELARKIQK 

       190        200        210        220        230        240 
NSLTEPIVND QVQIDSYYNA SSELSGDLYG YYQIDEHRYG IIILDVMGHG ISSALITMSL 

       250        260        270        280        290        300 
HPLFQRQITQ GLSPVKVMKE LDRHLHSLFQ NDEEARHYCT AIYLEIDIAR QRIDYVNAGH 

       310        320        330        340        350        360 
PPALWQDDSG TQHLLHATSP PIGMFEDLEF QSSSLSYTED GRLLLYTDGV MDPTASCYLF 

       370        380        390        400 
DLLKDHPDSP IADLKEKILT SLQHQKEAHH KSDDECFILV DVK 

« Hide

References

« Hide 'large scale' references
[1]Denizot F.
Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168.
[2]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.
[3]"A PP2C phosphatase containing a PAS domain is required to convey signals of energy stress to the sigmaB transcription factor of Bacillus subtilis."
Vijay K., Brody M.S., Fredlund E., Price C.W.
Mol. Microbiol. 35:180-188(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: CHARACTERIZATION.
Strain: 168 / Marburg / ATCC 6051 / DSM 10 / JCM 1465 / NBRC 13719 / NCIMB 3610 / VKM B-501.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z94043 Genomic DNA. Translation: CAB08010.1.
AL009126 Genomic DNA. Translation: CAB15416.1.
PIRG70038.
RefSeqNP_391291.1. NC_000964.3.

3D structure databases

ProteinModelPortalO07014.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224308.BSU34110.

Protein family/group databases

PptaseDBP3D0412162.

Proteomic databases

PaxDbO07014.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB15416; CAB15416; BSU34110.
GeneID936673.
KEGGbsu:BSU34110.
PATRIC18978824. VBIBacSub10457_3575.

Organism-specific databases

GenoListBSU34110. [Micado]

Phylogenomic databases

eggNOGCOG2208.
HOGENOMHOG000154204.
KOK01090.
OMAYHETHFA.
OrthoDBEOG689HN0.
PhylomeDBO07014.

Enzyme and pathway databases

BioCycBSUB:BSU34110-MONOMER.

Family and domain databases

InterProIPR001610. PAC.
IPR000014. PAS.
IPR001932. PP2C-like_dom.
[Graphical view]
PfamPF13426. PAS_9. 1 hit.
PF07228. SpoIIE. 1 hit.
[Graphical view]
SMARTSM00086. PAC. 1 hit.
SM00091. PAS. 1 hit.
SM00331. PP2C_SIG. 1 hit.
[Graphical view]
SUPFAMSSF55785. SSF55785. 1 hit.
SSF81606. SSF81606. 1 hit.
TIGRFAMsTIGR00229. sensory_box. 1 hit.
PROSITEPS50112. PAS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRSBP_BACSU
AccessionPrimary (citable) accession number: O07014
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: July 1, 1997
Last modified: July 9, 2014
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList