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Protein

Maltose phosphorylase

Gene

mdxK

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the phosphorolysis of maltose, leading to the formation of glucose and glucose 1-P.By similarity

Catalytic activityi

Maltose + phosphate = D-glucose + beta-D-glucose 1-phosphate.

Pathwayi: maltose degradation

This protein is involved in the pathway maltose degradation, which is part of Glycan degradation.
View all proteins of this organism that are known to be involved in the pathway maltose degradation and in Glycan degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei483Proton donorBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCarbohydrate metabolism

Enzyme and pathway databases

BioCyciBSUB:BSU34570-MONOMER
UniPathwayiUPA00150

Protein family/group databases

CAZyiGH65 Glycoside Hydrolase Family 65

Names & Taxonomyi

Protein namesi
Recommended name:
Maltose phosphorylase (EC:2.4.1.8)
Gene namesi
Name:mdxK
Synonyms:malK, yvdK
Ordered Locus Names:BSU34570
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001080181 – 757Maltose phosphorylaseAdd BLAST757

Proteomic databases

PaxDbiO06993
PRIDEiO06993

Interactioni

Protein-protein interaction databases

IntActiO06993, 1 interactor
STRINGi224308.Bsubs1_010100018726

Structurei

3D structure databases

ProteinModelPortaliO06993
SMRiO06993
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni354 – 355Substrate bindingBy similarity2
Regioni588 – 589Substrate bindingBy similarity2

Sequence similaritiesi

Belongs to the glycosyl hydrolase 65 family.Curated

Phylogenomic databases

eggNOGiCOG1554 LUCA
HOGENOMiHOG000055023
InParanoidiO06993
KOiK00691
OMAiEAYCIPF
PhylomeDBiO06993

Family and domain databases

Gene3Di1.50.10.10, 1 hit
2.70.98.40, 1 hit
InterProiView protein in InterPro
IPR008928 6-hairpin_glycosidase_sf
IPR012341 6hp_glycosidase-like_sf
IPR011013 Gal_mutarotase_sf_dom
IPR005194 Glyco_hydro_65_C
IPR005195 Glyco_hydro_65_M
IPR005196 Glyco_hydro_65_N
IPR037018 Glyco_hydro_65_N_sf
IPR017045 Malt_Pase/Glycosyl_Hdrlase
PfamiView protein in Pfam
PF03633 Glyco_hydro_65C, 1 hit
PF03632 Glyco_hydro_65m, 1 hit
PF03636 Glyco_hydro_65N, 1 hit
PIRSFiPIRSF036289 Glycosyl_hydrolase_malt_phosph, 1 hit
SUPFAMiSSF48208 SSF48208, 1 hit
SSF74650 SSF74650, 1 hit

Sequencei

Sequence statusi: Complete.

O06993-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MINQRLFEID EWKIKTNTFN KEHTRLLESL TSLANGYMGV RGNFEEGYSG
60 70 80 90 100
DSHQGTYIAG VWFPDKTRVG WWKNGYPEYF GKVINAMNFM GIGLYVDGEK
110 120 130 140 150
IDLHQNPIEL FEVELNMKEG ILRRSAVVRI QDKTVRIRSE RFLSLAVKEL
160 170 180 190 200
CAIHYEAECL TGDAVITLVP YLDGNVANED SNYQEQFWQE EAKGADSHSG
210 220 230 240 250
HLAAKTIENP FGTPRFTVLA AMANETEGFV HESFKTTEMY VENRYSYQTK
260 270 280 290 300
ASLKKFVIVT TSRDFREEEL LSKAKELLAD VVENGYEDAK RRHTDRWKER
310 320 330 340 350
WAKADIEIKG DEELQQGIRY NIFQLFSTYY GGDARLNIGP KGFTGEKYGG
360 370 380 390 400
AAYWDTEAYA VPMYLATAEP EVTKNLLLYR YHQLEAAKRN AAKLGMKGAL
410 420 430 440 450
YPMVTFTGDE CHNEWEITFE EIHRNGAICY AIYNYINYTG DRNYMEEYGI
460 470 480 490 500
DVLVAVSRFW ADRVHFSKRK NKYMIHGVTG PNEYENNVNN NWYTNVIAAW
510 520 530 540 550
TLEYTLQSLE SISAEKRRHL DVQEVELEVW REIIQHMYYP FSEELQIFVQ
560 570 580 590 600
HDTFLDKDLQ TVDELDPAER PLYQNWSWDK ILRSNFIKQA DVLQGIYLFN
610 620 630 640 650
DRFTMEEKRR NFEFYEPMTV HESSLSPSVH AILAAELKLE KKALELYKRT
660 670 680 690 700
ARLDLDNYNH DTEEGLHITS MTGSWLAIVH GFAGMRTANE TLSFAPFLPK
710 720 730 740 750
EWDEYSFNIN YRNRLINVTV DEKRVIFELV KGEPLHMNVY EEPVVLQGRC

ERRTPNE
Length:757
Mass (Da):88,279
Last modified:July 1, 1997 - v1
Checksum:i75B3ECE933850F29
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z94043 Genomic DNA Translation: CAB08040.1
AL009126 Genomic DNA Translation: CAB15462.1
PIRiC70034
RefSeqiNP_391337.1, NC_000964.3
WP_003243769.1, NZ_JNCM01000033.1

Genome annotation databases

EnsemblBacteriaiCAB15462; CAB15462; BSU34570
GeneIDi938621
KEGGibsu:BSU34570
PATRICifig|224308.179.peg.3744

Similar proteinsi

Entry informationi

Entry nameiMALPY_BACSU
AccessioniPrimary (citable) accession number: O06993
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: March 28, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health