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Protein

Sensor histidine kinase YvcQ

Gene

yvcQ

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Member of the two-component regulatory system YvcQ/YvcP. Probably activates YvcP by phosphorylation.1 Publication

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Two-component regulatory system

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBSUB:BSU34710-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Sensor histidine kinase YvcQ (EC:2.7.13.3)
Gene namesi
Name:yvcQ
Ordered Locus Names:BSU34710
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1111CytoplasmicSequence analysisAdd
BLAST
Transmembranei12 – 3221HelicalSequence analysisAdd
BLAST
Topological domaini33 – 4210ExtracellularSequence analysis
Transmembranei43 – 6321HelicalSequence analysisAdd
BLAST
Topological domaini64 – 356293CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 356356Sensor histidine kinase YvcQPRO_0000360785Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei136 – 1361Phosphohistidine; by autocatalysisPROSITE-ProRule annotation

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiO06979.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100018796.

Structurei

3D structure databases

ProteinModelPortaliO06979.
SMRiO06979. Positions 116-349.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini133 – 349217Histidine kinasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 histidine kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EWM. Bacteria.
COG0642. LUCA.
HOGENOMiHOG000032012.
InParanoidiO06979.
KOiK00936.
OMAiSEHTEKV.
PhylomeDBiO06979.

Family and domain databases

Gene3Di3.30.565.10. 1 hit.
InterProiIPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR004358. Sig_transdc_His_kin-like_C.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF55874. SSF55874. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O06979-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKTYLIDRL AIILFSLLGI GSAMLIAYLS IVESGAEPSK ENMMYIWILP
60 70 80 90 100
GTLLAAGFAA DYVRQFSFLT YVKKLAEQAS SSNDIGQSLK ARKPRTGEQA
110 120 130 140 150
LWTKMINALG QQYESRLSQY INQQKQHYTF TNQWVHHMKT PVSVISLMIQ
160 170 180 190 200
EGKNGTSSSF PTFLEELEDE NERFRHGLDM MLQTARLEEF AFDVKPQTFD
210 220 230 240 250
LAEMVRSLIN QEKRQFIKRR LFPTLHVPPN AVQISSDQKW LSFVVEQILF
260 270 280 290 300
NALKYSKQGV GDPITIRIET QGHETRLSVA DEGIGIPPQD LPRIFDAFFT
310 320 330 340 350
GENGRTMKEA TGMGLYLAKQ VCSRLGHKLY AESKEGAGTV MTIVFSSDTL

VNVTAL
Length:356
Mass (Da):40,180
Last modified:July 1, 1997 - v1
Checksum:i6A707CC99BBD00D8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z94043 Genomic DNA. Translation: CAB08063.1.
AL009126 Genomic DNA. Translation: CAB15476.1.
PIRiE70032.
RefSeqiNP_391351.1. NC_000964.3.
WP_003242699.1. NZ_JNCM01000033.1.

Genome annotation databases

EnsemblBacteriaiCAB15476; CAB15476; BSU34710.
GeneIDi938024.
KEGGibsu:BSU34710.
PATRICi18978946. VBIBacSub10457_3635.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z94043 Genomic DNA. Translation: CAB08063.1.
AL009126 Genomic DNA. Translation: CAB15476.1.
PIRiE70032.
RefSeqiNP_391351.1. NC_000964.3.
WP_003242699.1. NZ_JNCM01000033.1.

3D structure databases

ProteinModelPortaliO06979.
SMRiO06979. Positions 116-349.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100018796.

Proteomic databases

PaxDbiO06979.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB15476; CAB15476; BSU34710.
GeneIDi938024.
KEGGibsu:BSU34710.
PATRICi18978946. VBIBacSub10457_3635.

Phylogenomic databases

eggNOGiENOG4105EWM. Bacteria.
COG0642. LUCA.
HOGENOMiHOG000032012.
InParanoidiO06979.
KOiK00936.
OMAiSEHTEKV.
PhylomeDBiO06979.

Enzyme and pathway databases

BioCyciBSUB:BSU34710-MONOMER.

Family and domain databases

Gene3Di3.30.565.10. 1 hit.
InterProiIPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR004358. Sig_transdc_His_kin-like_C.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF55874. SSF55874. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYVCQ_BACSU
AccessioniPrimary (citable) accession number: O06979
Secondary accession number(s): Q795G1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: July 1, 1997
Last modified: September 7, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.